Term
|
Definition
double walled, fluid filled, visceral pleura is closest to lung, parietal pleura is closest to thoracic wall |
|
|
Term
Describe trachea and larger bronchi |
|
Definition
rigid, nonmuscular tube. C-shaped cartilage to prevent collapse |
|
|
Term
|
Definition
thin-walled inflatable sacs, consisting of a single layer of Type 1 alveolar cells |
|
|
Term
what are alveoli surrounded by? |
|
Definition
|
|
Term
Out of the three important pressures in ventilation, which is always the lowest? |
|
Definition
|
|
Term
|
Definition
collection of air in the pleural cavity-puts pressure on the lungs |
|
|
Term
|
Definition
collection of blood in the pleural cavity-puts pressure on mediastinum/trachea/heart ventricles |
|
|
Term
name pressure conditions for air to enter the lungs |
|
Definition
intra-alveolar pressure is less than atmostpheric pressure |
|
|
Term
percentage of body's energy used to inspire? |
|
Definition
|
|
Term
major muscles of inspiration |
|
Definition
diaphragm (phrenic nerve) and external intercostal muscles (intercostal nerve) |
|
|
Term
when the diaphragm contracts, what happens to it, lungs, and pressure? |
|
Definition
diaphragm lowers, thoracic cavity expands, lungs expand which causes the pressure to decrease below atmostpheric pressure and air enters lung |
|
|
Term
Pulmonary fibrosis ______ compliance |
|
Definition
|
|
Term
Effect on bronchioles of parasympathetic stimulation? |
|
Definition
|
|
Term
effects on bronchioles of sympathetic stimulation? |
|
Definition
|
|
Term
If there are high levels of CO2, what happens to bronchioles? |
|
Definition
|
|
Term
if there are low levels of CO2, what happens to bronchioles? |
|
Definition
|
|
Term
epinephrine's effects on bronchioles? |
|
Definition
|
|
Term
what happens to the volume of the chest cavity during expiration |
|
Definition
|
|
Term
what happens to the inrapleural pressure during expiration? |
|
Definition
increases (muscles are relaxation -coming in -so puts pressure on the cavity) |
|
|
Term
what happens to intra-alveolar pressure during expiration |
|
Definition
|
|
Term
when intra-alveolar pressure exceeds atmospheric pressure, what happens? |
|
Definition
air is forced out = expiration |
|
|
Term
what are the expiratory muscles? |
|
Definition
diaphragm and internal intercostal muscles |
|
|
Term
what is forced expiration? |
|
Definition
contraction of expiratory muscles (diaphragm and internal intercostal muscles) |
|
|
Term
What 2 factors does elastic recoil depend on? |
|
Definition
elastic CT in lungs Alveolar surface tension |
|
|
Term
what causes alveolar surface tension? |
|
Definition
a thin liquid film lines each alveolus |
|
|
Term
what are the effects of alveolar surface tension? |
|
Definition
reduces tendency for alveoli to expand (minimizes size) |
|
|
Term
|
Definition
loss of elastic tissue (esp alveoli) alveoli walls collapse--barrel chest |
|
|
Term
|
Definition
difficult expiring>>forced expiration>>airways collapse>>air trapped in lungs>>barrel chest |
|
|
Term
During quiet normal breathing (expiration), describe intrapleural and intra-alveolar pressures |
|
Definition
Intrapleural: lower than intra-alveolar Intra-alveolar: slightly higher than atmosphereic and higher than intra-pleural |
|
|
Term
During expiration, describe pressure during exercise |
|
Definition
intrapleural: elevated intra-alveolar: elevated and slightly above intra-pleural |
|
|
Term
During expiration, describe pressures during maximal forced expiration: |
|
Definition
intrapleural: very elevated intra-alveolar:very elevated-slightly higher than intrapleural
**narrow airways |
|
|
Term
during expiration, describe pressures in patients with obstructive lung disease |
|
Definition
intrapleural: very elevated intra-alveolar: elevated (higher than intrapleural)--looks the same as if were doing exercise |
|
|
Term
What is Newborn Respiratory Distress Syndrome? |
|
Definition
insufficiency of surfactant production>>>collapse of alveoli
low compliance>>>have trouble inflating their lungs |
|
|
Term
what percentage of lung is filled w air during normal breathing? |
|
Definition
|
|
Term
when elastic coil is decreased (emphysema) what happens |
|
Definition
|
|
Term
|
Definition
graph that records inspiration and expiration |
|
|
Term
What is inspiratory reserve volume? |
|
Definition
extra volume of air that can be maximally inspired over the typical tidal volume (3000 mL) |
|
|
Term
what is expiratory reserve volume? |
|
Definition
volume of air that can be maximally expired after normal tidal volume has been expired (1000 mL) |
|
|
Term
|
Definition
minimum volume of air leftover after a maximal expiration (1200 mL) |
|
|
Term
what is functional residual capacity? |
|
Definition
volume of air in lungs after normal passive expiration (2200 mL)
the residual volume + expiratory reserve volume |
|
|
Term
|
Definition
MaX Volume of air that can be moved out during a single breath following a maximum inspiration (take tidal volume add to it the IRV then add to that the ERV) |
|
|
Term
|
Definition
max volume of air the lungs can hold (vital capacity plus the residual volume) |
|
|
Term
|
Definition
forced expiratory volume in first second in a Vital Capacity determination |
|
|
Term
what's the normal volume of air in the lungs after inspiration? after expiration? |
|
Definition
|
|
Term
what is the value of the total lung capacity? |
|
Definition
|
|
Term
what is the value of residual volume (minimum amount of air in lungs) |
|
Definition
|
|
Term
what does COPD do to Functional Residual capacity? |
|
Definition
increases it (air is left over after you expire bc the airways collapse and ther is air sitll left in alveoli) |
|
|
Term
what does COPD do to residual volume? |
|
Definition
increases it (can't exhale fully bc air is trapped from collapsed airways) |
|
|
Term
What does COPD do to vital capacity? |
|
Definition
decreases it (can't exhale enough) |
|
|
Term
what does COPD do to FEV1? |
|
Definition
significantly reduces it because there's more resistance and air can't be exhaled as much |
|
|
Term
What does restrictive/less compliant lung do to total lung capacity? |
|
Definition
decreases (can't inhale as much) |
|
|
Term
What does restrictive/less complaint lung do to vital capacity? |
|
Definition
decreases (can't inhale as much) |
|
|
Term
what does restrictive/less compliant lung to do FEV1? |
|
Definition
nothing-you don't have problems exhaling and the rate is the same |
|
|
Term
what is pulmonary ventilation? |
|
Definition
air breathed in and out in one minute |
|
|
Term
equation for pulmonary ventilation? |
|
Definition
tidal volume x respiratory rate |
|
|
Term
what are the effects of impaired bulbar muscles? |
|
Definition
aspiration of food particles |
|
|
Term
what is alveolar ventilation? |
|
Definition
volume of air exchanged between the atmosphere and alveoli per minute |
|
|
Term
is alveolar ventilation greater or less than pulmonary ventilation? |
|
Definition
less than due to anatomic dead space |
|
|
Term
what is anatomic dead space? |
|
Definition
volume of air in conducting pathways which is useless for exchange (150 mL) |
|
|
Term
equation for alveolar ventilation? |
|
Definition
= (tidal volume - dead space) x respiratory rate |
|
|
Term
Similarity and Difference between quiet breathing at rest and deep slow breathing? |
|
Definition
pulmonary ventilation is the same (taking in the same amount of air) alveolar ventilation is greater in deep breathing bc you are taking more oxygen in at each breath |
|
|
Term
similarity and difference between quiet normal breathing and short shallow breathing? |
|
Definition
pulmonary ventilation is the same (amount of air taken in is the same) but alveolar ventilation is much higher in normal breathing bc in short rapid breathing, the oxygen does not reach the respiratory bronchioles |
|
|
Term
even though CO2 has a lot smaller partial pressure gradient for gas exchange than O2, why are equal amounts of CO2 and O2 exchanged? |
|
Definition
|
|
Term
what is the main factor in determining hemoglobin saturation? |
|
Definition
partial pressure of oxygen |
|
|
Term
in an area of low PO2, where does oxygen go? |
|
Definition
dissociates form Hb (tissues) |
|
|
Term
in an area of high PO2, where does O2 go? |
|
Definition
|
|
Term
|
Definition
|
|
Term
the production of BPG does what to oxygen? |
|
Definition
kicks it off of Hb aka moves Oxygen dissociation curve to the right and delivers more oxygen to tissues |
|
|
Term
what type of CT exists the entire way down the respiratory tract? |
|
Definition
|
|
Term
|
Definition
having low oxygen levels at cell level |
|
|
Term
|
Definition
low O2 levels bc of respiratory issues |
|
|
Term
|
Definition
reduced O2 carrying capacity of blood |
|
|
Term
|
Definition
decreased amount of blood delievered to tissues |
|
|
Term
|
Definition
cells cannot use own oxygen |
|
|
Term
|
Definition
having above normal O2 in arteroile blood |
|
|
Term
|
Definition
having excess CO2 in arteriole blood |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
hyperventilation -fever -anxiety |
|
|
Term
name 2 respiratory control centers in the brain stem |
|
Definition
pons respiratory centers and medullary respiratory centers |
|
|
Term
what are the 2 centers in the pons respiratory centers? |
|
Definition
pneumotaxic center and apneustic center |
|
|
Term
what are the 2 centers in the medullary center? |
|
Definition
dorsal respiratory group and ventral respiratory group |
|
|
Term
which center generates breathing rhythm |
|
Definition
|
|
Term
which respiratory group is active during normal passive inspiration? |
|
Definition
|
|
Term
which respiratory group is active in active inspiration and esp active respiration? |
|
Definition
ventral respiratory group |
|
|
Term
what are the pacemaker-like cells |
|
Definition
|
|
Term
which centers regulate magnitude of breathing? |
|
Definition
|
|
Term
what does the pneumotaxic center do? |
|
Definition
sends impulses to dorsal regulatory group to turn off inspiratory neurons for smooth breathing |
|
|
Term
what does the apneustic center do? |
|
Definition
blocks pneumotaxic center |
|
|
Term
what does the Hering-Breuer reflex do? |
|
Definition
prevents over-inflation of lungs (inhibits DRG when lungs stretch) |
|
|
Term
what value does PO2 have to be at for peripheral receptors to become sensitive? |
|
Definition
|
|