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Test 5 Pharm (ch. 48-51)
Dermatologic Agents
24
Pharmacology
Undergraduate 2
04/15/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Acne Vulgaris
Definition

-most common disorder in US

 

-keratin plug at base of pilosebaceous oil glands

 

-non-pharmacologic: gentle cleansing qid, well-balanced diet, decrease stress

 

-topical & systemic agents

Term
benzoyl peroxide (Clearasil)
Definition
-topical agent for acne vulgaris, bid
Term
tretinoin (Retin-A)
Definition

-topical agent for acne vulgaris

 

-derivative of vitamin A

Term
Salicyclic acid
Definition
-topical agent for acne vulgaris, bid
Term
adapalene (Differin)
Definition

-topical agent for severe acne

 

-antiinflammatory & eliminates blackheads

 

-SE: photosensitivity

Term
Moderate acne
Definition
-tx w/ tetracycline, clindamycin, & erythromycin gels
Term
Systemic agents for severe acne
Definition

-oral antibiotics (tetracycline, erythromycin)

 

-isotreintoin (Accutane) - warning: increased risk of suicide

Term
Psoriasis
Definition

-chronic skin disorder

 

-overgrowth of skin cells w/ plaques forming on flexor surfaces & other skin ares

 

-topical & biological agents used

Term
Salicyclic acid
Definition
-topical keratolytic for psoriasis
Term
coal tar (PsoriGel)
Definition
-topical agent for mild-moderate psoriasis
Term
Dovonex
Definition

-vitamin A derivative tx for psoriasis

 

-adverse: hypercalcemia, hypercaluremia

Term
Methotrexate
Definition
-anticancer agent used for tx of psoriasis; slows growth
Term
UVA light therapy
Definition
-used to tx psoriasis by suppressing cell division
Term
psoralen & UVA
Definition
-photochemical therapy used to decrease proliferation of cells of psoriasis
Term
Biologic Agents for Psoriasis
Definition

-infliximab (Remicade)-for inflammation, autoimmune disorders

-etanercept (Enbrel)-TNF-alpha inhibitor

-adalimumab (Humira)

-efalizumab (Raptiva)

 

-watch for signs of infection; do not give meds

Term
Verruca Vulgaris (Warts)
Definition

-hard, horny nodule

 

-tx: freezing (liquid nitrogen), electrodesication (cautery/laser), surgical excision, salicylic acid, podophyllum resin (venereal warts), cantharidin (Cantherone)

Term
Drug-induced Dermatitis
Definition

-rash, vesicles, papules, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis

 

-drugs: INH, hydrazaline, anticonvulsants, antidysrhythmics (Pronestyl)

Term
Contact Dermatitis
Definition

-chemical or plant irritation

 

-perfume, dyes, clothing, cosmetics, poison ivy, poison oak, sumac

Term
OTC for Contact Dermatitis
Definition
-Calamine, Borrow's solution, oatmeal bath, glucosteroids ointments
Term
Rx for Contact Dermatitis
Definition

-topical steroids (Codran, Decadron, Aristocort)

-oral steroids (Medrol Dosepak)

Term
Alopecia
Definition

-hair loss

 

-drugs: minoxidil (Rogaine)-topical, men only

 

-finasteride (Propecia)-tablet for BPH, works better in younger men

Term
Sunscreens
Definition

-protect against UVA & UVB rays

 

-examples: Anthelios Sx Daily Moisturizing Cream w/ sunscreen, Pre-sun ultra screen, Sea & Ski Advanced sunscreen, Nutrogena Ultra Sheer Dry-Touch Sunblock

 

-SPF 15 is best protection

-apply 30 mins prior to exposure

-protects for about 2 hours when applied properly

Term
*mafenide (Sulfamylon)
Definition

-antiinfective for 2nd & 3rd degree burns

 

-dose: apply thin layer bid

 

-SE: rash, burning/stinging, urticaria, edema

 

-adverse: bone marrow suppression, fatal hemolytic anemia

Term
silver sulfadiazine (Silvadene)
Definition
-antiinfective for burns
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