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blood is normally sterile bacteremia is when bacteria appear in blood -ex: brushing teeth |
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bacteria in blood causing an immune response (inflammatory) in the blood --sepsis/septic shock ---decreased bp, organ failure most often bacillus exotoxin triggers immune reaction>shock>death |
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inflammation -inner epitelial layer of the heart esp heart valve strep throat>theumatic fever> endocarditis damaged heart valve |
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2 types of bacterial endocarditis |
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Definition
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Acute bacterial endocarditis |
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rapid onset symptoms -shaking chills, spiking fever high fatality rate --needs prompt aggressive treatment ---antibiotics damaged or normal heart valve involved S. aureus, S. pyogenes, N. gonnorhea |
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Subacute bacterial endocarditis |
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slower onset -bacteria piles up on valve low grade fever, fatigue, anemia involves mainly damaged valves and normal bacteria of mouth and throat |
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autoimmune complication of group a beta hemolytic strep infection -may be genetic occurs 2-3 weeks after strep throat -fever, arthritis, rash,heart damage |
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Clostrida spp. endospores soil bacteria -easy to get into wounds obligate anerobe-grows in damaged,dead, low o2 areas. |
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C. prefringens gas gangrene -ferments sugars -pockets of gas in tissue -hydrogen/co2 -crackling noise fatal untreated penicillin |
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domestic animals dogs, cats -Pasturella multocida local infection, pneumonia, septicemia Humans>bites/clenched fist injuries often worse than animal bite 5% require amputation |
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S. Aureus bacteroides Fusobacterium septicemia, tissue destruction, inflammation, swelling |
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Yersinia pestis gram neg Killed large number of people vector rat flea both ill resevoir rats -rodents-mice, squirrels, beavers.. |
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Borrelia burgdorferi vector tick -Ixodes reservoir -field mice, other no person to person rash at bite site, sometimes flue like symptoms longer last, more damage, hard to treat |
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in everybody normally ok Mononucleosis -fever, sore throat, swollen neck, lymph nodes, enlarged spleen usually self healing saliva transmission mild in children severe in adults |
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chronic fatigue syndrome Burkitts lymphoma -B cell cancer |
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protist taxoplasma gondii sex mature in cat intestines shed in cat feces unlikely in indoor cat bad for pregnany women, damage/death to fetus |
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plasmodium spp -4 spp 300-500 million effected worldwide 20-40 million die P. falciparum most dangerous characteristic schedule every 38 to 48 hrs depending on specie last 6 hrs chills fever |
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blood flukes millions worldwide heart disease, epilepsy, kidney failure, cirrhosis of liver -fever, rash,body pains, cough,dysentry stays 30 yrs lays 3500 eggs/day eggs in intestine/bladder-leave eggs in body-bad |
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2 Parts of respiratory system |
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Definition
upper -nose, throat, middle ear Lower -larynx trachea, bronchial tubes, alveoli |
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Definition
group a beta hempolytic s.pyogenes respiratory route resist phagocytosis penicillin effective could cause rheumatic fever and glomerulonephritis |
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rhinoviurs 113 kinds likes cooler body temp 33-34C upper respiratory epithelium corona virus |
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mycobacterium tuberculosis acid fast respiratory route long generation time -33 hrs sensitive to uv/ sunlight resist drying out, last long onsurface macrophage unable to digest it multiplies inside macrophage |
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inflammation of lung tissue typical pneumonia -strep pneumoniae atypical mycolasma, chlamydia, virus |
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most common strep pneumonia capsule diplococcus fever, chest pain, rust colored sputum vaccine of purified capsular material |
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no cell walls cholesterol in membrane smallest free living bacteria walking pneumonia -low grade fever, dry cough, headache |
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associated with birds Chlamidia psittaci -obligate intracellular parasite 2 forms-out cell, inside cell contact with bird droppings |
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often complication of measels, chicken pox respiratory syncytial virus most common pneumonia in infants |
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8 pandemics since 1889 kills healthy people RNA virus, capsule with spikes hemagglutin, helps attatch Neuraminidase, helps release treatment-guess of which type will come |
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reservoir mice breathe air contaminated with dropping ok morning, respirator afternoon, dead night pulmonary edema to death |
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fungus Coccidiodes immitis dimorphic soil fungus -spores carried by wind SW us/california symptoms like TB |
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usually opportunistic Factors: disorders of the nervous system Diabetes Obstruction of urine flow closeness of intestinal gram neg bacteria, especially in females |
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inflammation of urinary bladder usually more common infemales due to shorter urethra dysuria-painful urination pyruia-leukocytes in urine Ecoli, staph saphrophyticus |
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Definition
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gram neg Neisseria gonnorrhea in females-most asymptomatic attatch to mucosal cells by fimbrae/pili complications occur if it goes systemic infected mother-baby becomes blind antibiotics in eyes |
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Non gonococcal urethritis |
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Definition
caused by chlamydia trachomatis 40 acquired thru sex usually mild/asymptomatic sterility may occur |
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Definition
spirochate, trponema pallidum several stages to disease. -Primary chancre -secondary rash -tertiary gumma |
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usually opportunistic Factors: disorders of the nervous system Diabetes Obstruction of urine flow closeness of intestinal gram neg bacteria, especially in females |
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Definition
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Definition
inflammation of urinary bladder usually more common infemales due to shorter urethra dysuria-painful urination pyruia-leukocytes in urine Ecoli, staph saphrophyticus |
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Definition
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Definition
gram neg Neisseria gonnorrhea in females-most asymptomatic attatch to mucosal cells by fimbrae/pili complications occur if it goes systemic infected mother-baby becomes blind antibiotics in eyes |
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Term
Non gonococcal urethritis |
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Definition
caused by chlamydia trachomatis 40 acquired thru sex usually mild/asymptomatic sterility may occur |
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Term
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Definition
spirochate, trponema pallidum several stages to disease. -Primary chancre -secondary rash -tertiary gumma |
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