Term
what receptors do atropine and scop block? |
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Definition
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Term
you pair atropine with what AcHe Inhibitor |
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Definition
Atropine goes with edrophonium |
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Term
glycopyrrolate pairs with what two drugs? |
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Definition
1. neostigmine 2. pyridostignmine |
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Term
with large doses of anticholinergics what sx occur |
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Definition
inhibits micturition, gastric Hydrogen ion secretion and gut motility. |
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Term
adult dose of atropine in the OR is? |
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Definition
0.4mg IV. For a code its 1mg. do no exceed 3mg. |
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Term
pedi dose for atropine is? |
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Definition
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Term
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Definition
half life of 2-4 hours, can cross BBB, high doses can cause CNS effects such as restlessness, delirium, coma, renal excretion, |
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Term
IM Atropine dose adult? Pedi? |
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Definition
adult 1-2mg pedi 20-40mcg kg |
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Term
does atropine increase or decrease baroreflex? explain |
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Definition
it decreases, b/c since atropine increases your HR it also increases your blood pressure. The baroreflex normally regulates this by decreasing your HR when it senses increase BP. So atropine disables this |
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Term
Does atropine cross the placenta |
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Definition
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Term
why does atropine increase your risk for emesis? |
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Definition
it lowers the tone to your lower esophageal sphincter tone |
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Term
which is more sedating atropine or scop |
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Definition
scop. so dont give to elderly |
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Term
which is ok to give to pt with glaucoma |
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Definition
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Term
overdose of atropine or scop will result in these sx |
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Definition
1. dilated pupils 2. dry mucosa 3. dry flushed skin 4. head ache 5. increased HR 6. blurred vision 7. ataxia 8. restlessness 9. coma |
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Term
what drug can you give to treat an anticholinergic overdose. What dose? |
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Definition
physostigmine b/c it can cross the BBB, 1mg IV. Benzo for seizures, ventilator support if needed. |
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Term
what is central anticholinergic syndrome? trt with? |
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Definition
similar to atropine overdose except pt is motionless and depression is set in. decrease resp drive, treat with physostigmine 1mg IV |
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Term
whats the mneumonic for anticholinergic toxicity |
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Definition
ANTICHOLINERGIC TOXICITY FROM ATROPINE: blind as a bat, mad as a hatter, red as a beat, hot as hades, dry as a bone, bowel and bladder loose their tone, and the heart runs alone. |
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Term
whats the conc of neo + gly. |
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Definition
for every 1mg of neostig given 0.2 glyc |
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Term
Which anticholinergic is most likely to cause emesis..why |
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Definition
glyc, can cause b/c it decreases the lower esophageal tone. |
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Term
name a anticholinergic drug used for parkinsonianism |
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Definition
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Term
meperidine and benadryl share what in common? |
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Definition
both are antimuscarinic. (hence the CNS since they also act centrally) |
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Term
what is cogentin used for? |
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Definition
It is an anticholinergic used for alzheimers, treats also extrapyrimidial side effects from reglan or other antipsychotics |
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Term
how does atropine and scop effect the resp |
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Definition
bronchodilation, decreases airway resistance and blunts the hyperresponsiveness of respt tracts, also decrease mucous secretion |
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