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Superficial, thinner portion Keratinized stratified squamous epithelial tissue Provides protection, a barrier |
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Deeper, Thicker portion Connective tissue |
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Deep to the dermis Areolar, adipose tissue Fat storage, large blood vessels |
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Hyperdermis, subcutaneous layer |
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Palms, palmar surfaces of the fingers, soles Epidermis is relatively thick, 0.6-4.5 mm Sensory receptors are more dense Numerous sudoriferous glands, no sebaceous glands |
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Definition
Thick skin - Hairless skin |
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Everywhere else Thin epidermis, 0.10 - 0.15 mm |
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Most numerous, produce keratin (a tough protein), waterproofing |
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produce melanin (a brown-black pigment) |
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Small number, immune response |
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Deepest Layer Single row of cells keratinocytes, some are stem cells that constantly divide Melanocytes Merkel cells |
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8-10 layers of keratinocytes Appear spiny in histology slides Langerhans cells and Melanin granules |
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3-5 layers of flattened keratinocytes undergoing apoptosis |
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3-5 layers of clear, flat, dead keratinocytes |
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25-30 layers of dead, flat keratinocytes that are continuously shed |
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THE DERMIS - One fifth of the dermis Aerolar connective tissue Dermal Papillae |
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THE DERMIS- Dense irregular connective tissue Hair follicles, sudoriferous and sebaceous glands |
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PIGMENT - Protection from UV light Pale yellow to tan to black The number of melanocytes is relatively constant, the amount of melanin produced varies Freckles, age (liver) spots, nevus or mole (benign overgrowth of melanocytes) |
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PIGMENT - Yellow-orange pigment, precursor for vitamin a |
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PIGMENT - Red color, pigment in blood |
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SUDORIFEROUS/Sweat Glands: In most skin Secretory portion in dermis with pore at surface of epidermis Helps regulate body temp. |
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SWEAT GLANDS - Found mostly in axilla, groin, areola, beard area in males; don’t function until puberty Secretory portion in hypodermis with ducts opening into hair follicles Secretions are similar to that of eccrine sweat glands with the addition of proteins and lipids Secrete during stress or sexual excitement |
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Connected to hair follicles Secrete sebum, an oily substance Coats hairs to keep them from drying out Prevents excessive evaporation of water from the skin Keeps the skin soft and pliable Inhibits the growth of certain bacteria |
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Secrete waxy substance that combines with sebum to produce cerumen, earwax |
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Plates of tightly packed, hard, keratinized epidermal cells |
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Dermal papilla Fine touch, pressure, slow vibrations |
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Definition
Meissner corpuscles (corpuscles of touch) |
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Epidermis Touch and pressure |
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Definition
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Dermis, ligaments, tendons Stretching of skin |
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Definition
Ruffini corpuscles (type II cutaneous mechanoreceptors) |
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Dermis, hypodermis, joints, some viscera Pressure, fast vibrations, tickling |
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Definition
Pacinian corpuscles (lamellated corpuscles) |
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WOUND HEALING -
Eliminates microbes, foreign material, dying tissue Increased permeability, vasodilation WBCs enter tissue, phagocytize |
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WOUND HEALING - Blood cot dries to scab, Epithelial cells bridge the gap Fibroblasts synthesize collagen and glycoproteins in the dermis Granulation tissue = fibrous CT filling the wound Damaged blood vessels regrow |
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WOUND HEALING - Growth of epithelial cells, fibroblasts deposit collagen, vessels grow |
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WOUND HEALING - Scab sloughs off, granulation tissue becomes scar tissue |
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