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Pharmacology
Undergraduate 3
09/22/2014

Additional Pharmacology Flashcards

 


 

Cards

Term
postictal
Definition
following a seizure - can be unconscious for several minutes
Term
Clonic/tonic
Definition
seizure - stiffening of the muscles
Term
aura
Definition
comes before a seizure
Term
EEG
Definition
test used for seizures - electroencephalgram
Term
general seizure
Definition
affects the whole body
Term
partial seizure
Definition
affecting one area of the body
Term
3 classifications of seizures
Definition
partial, general, special syndromes
Term

(Imitrex) Sumatriptan

 

Definition

Anti migraine, Pregnancy Category C

Seratonin Agonist, vasoconstrictor of vessels

causes: dizziness, drowsiness, warm feeling

Term
pharmacotherapeutic approach of preventing migraines
Definition
botox, triggers can include asian food, redwine and coffee
Term
Migraine
Definition
throbbing, pulsating more common in women
Term

other NSAIDS:

Ibuprofen (Advil)

naproxen (Aleve)

celecoxib (Celebrex)

 

Definition
releive pain and swelling but not fever
Term
(Ultram) tramadol
Definition

synthetic opioid

analgesic

binds to mu

causes dizziness, constipation and drowsiness

Term
(Tylenol) acetaminophen
Definition

non-narcotic, antipyretic

analgesic
inhibits prostaglandins

causes hepatoxicity, nausea

can cause irreversible liver damage

Term
Aspirin
Definition

non-opioid,nsaid, antipyretic

cox inhibitor

can cause gastric discomfort, tinnitus, Reye Syndrome, gi bleeding

Term
Respiratory Depression
Definition
can stop breathing use a monitor
Term
Buprenorphine
Definition

Analgesic

opioid agonist - antiagonist

sedation and dizziness

 

given to addicts - helps with pain but not as strong

Term
(Narcan) naloxone
Definition

treats opioid overdose

opioid antagonist

bocks both mu and kappa

rapid loss of analgesic - will feel pain

 

if a drug user or high tolerance - could throw them into with drawyls

Term
(Dilaudid) Hydromorphone
Definition

opioid,analgesic, antitussive

binds to opioid receptors

 

causes drowsiness, dizziness, respiratory depression

 

more potent than morphine

Term
(Duramorph) Morphine
Definition

opioid agonist

binds with mu or kappa

causes nausea, vomitting, sedation

 

watch for respiratory depression

Term

Fentanyl

(Actiq, duragesic, ionsys)

Definition

similar to morphine

break thru pain

can have a transdermal with battery attached and gives electrical charge

 

monitor with apnea machine

Term
(Eskalith) lithium carbonate
Definition

mood stabalizer

seratonin antagonist - glutamate inhibitor

inhibits excitatory neurotransmitters

 

can cause polydipsia, polyuria, nausea, wt gain

 

Renal and liver study need to be done, limit alcohol and caffeine

 

Term

(Ritalin) methylphenidate

 

Definition

antipsychotic, schizophrenia

dopamine antagonist

 

agitation and anxiety

 

black box for elderly

Term
(Haldol) haloperidol
Definition

antipsychotic, schizophrenia

dopamine antagonist

blocks dopamine

 

blurred vision, constipation

 

black box for elderly

Term
(Thorazine) chlorpromazine
Definition

antipsychotic, schizophrenia

dopamine antagonist

 

blocks dopamine

drowsiness, constipation, extrapyramidals

 

risk of death in elderly, alzheimers

Term

(Effexor) venlafaxine

 

Definition

antidepressant SNRI

seratonin - norepinephrine reuptake inhibitor

blocks both

 

nausea dry mouth drowsiness

 

tremors, sweating, seratonin syndrome if given too much

Term
(Nardil) phenelzine
Definition

antidepressant

MAOI monoamine oxidase inhibitor

inhibits oxidase and increases norepinephrine

 

hypertension, crisis with some foods

Term
(Zoloft) sertraline
Definition

antidepressant

SSRI - selective seratonin reuptake inhibitor

block reuptake of seratonin

 

headache nausea wt gain sexual dysfuntion

 

do not use grapefruit juice

black box warning

Term
(Trofranil) imipramine
Definition

antidepressant

tricyclic - blocks reuptake of both seratonin and norepinephrine

 

hypotension

 

black box warning

suicidal tendancies

Term
(Cerebyx) fosphenytoin
Definition

antiseizure

hydantoin

stabalizes neurologic membranes

 

drowsiness

 

body turns this into dilantin

Term
(Neurotin) gabapentin
Definition

anticonvulsant, antineuralgic

increases synthesis, accum of gaba

 

fatigue, drowsiness

 

watch for seizures, dont stop suddenly

Term
(Dilantin) phenytion
Definition

antiseizure, antidysrythmic

hydantoin

affects sodium channels and decreases spread of electrical discharges

 

heart dysrythmias, drowsiness, slurred speech, confusion

 

can cause nystagmus, gingival hyperplasia, monitor blood levels, stevens johnson syndrome

Term
(Valium) dizepam
Definition

antiseizure

benzodiazapine

gaba agonist, enhances gaba

supresses limbic system and RAS

 

USE: Status Epilepticus

can cause drowsiness, and can be repeated every 10-15 minutes

Term
(Lumina) phenobarbital
Definition

antiseizure

barbiturate

gaba agonist

enhance gaba

 

drowsiness, anxious, restless

Do not drink alcohol, risk of dependence, do not stop suddenly

Term
nocieptive pain
Definition

shar, throbbing

well localized

visceral - generalized dull

Term
analgesics
Definition
decrease pain
Term

opioid classifications:

 

agonists

Definition
block pain
Term

opioid classifications:

 

agonist - antagonist

Definition
decrease pain but not as strong, often given to addicts, ex. buprenorphine
Term

opioid classifications:

 

antagonists

Definition

reverse opioids

ex.narcan

Term
akathisia
Definition
constant pacing
Term
parkinsonism
Definition

symptoms of parkinsons

pilln rolling with fingers, shuffling feet, mask face, slow moving and talking

Term
tardive dyskinesia
Definition

bazaar tongue and face movements

exaggerated movements (Chewing)

Term
anticholinergic effects
Definition
dry mouth, blurred vision, photo phobia
Term
neuroleptic malignant syndrome
Definition

medical emergency

increased fever, muscle rigidity, mental confusion

Term
acute dystonia
Definition
painful muscle spasms of face, neck, upper back and tongue
Term
postive symptoms of schizophrenia
Definition

added to normal behavior

ex. increased talking

Term
negative symptoms of schizophrenia
Definition
laziness, appear depressed
Term
CVA
Definition

cerebral vascular accident

interruption of blood flow

damage is permanent

Term
TIA
Definition

transient ischemic attack

no long term effects

Term
gingival hyperplasia
Definition

overgrowth of gum tissue

dilantin can cause

Term
stevens-johnson syndrome
Definition

severe skin reaction - swelling and blisters

flu like symptoms

dilantin can cause

Term
nystagmus
Definition

involuntary movement of the eye (back and forth)

dilantin can cause

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