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Proportion of phenotypic variation due to additive gene effects |
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average age of the parents when the offspring are born |
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mating based on phenotypic resemblance |
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best + best, worst + worst. Increases variation, produces extreme individuals |
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best + worst. results in phenotypic uniformity |
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mating of individuals more closely related than under random mating |
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mating of genetically unrelated animals |
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Inbreeding coefficient (F) |
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probability that the two genes at a locus in individual are identical by descent. Half the relationship between parents of the individual |
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both alleles from common ancestor |
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F of full sibs/ parent-child |
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F= 1/4, genes in common= 1/2 |
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F= 1/8, genes in common= 1/4 |
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F of 3rd degree (eg. 1st cousins) |
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F= 1/16, genes in common= 1/8 |
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F of 4th degee (eg. 1st cousins once removed) |
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F= 1/32, genes in common= 1/16 |
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F of 5th degree (eg. 2nd cousins) |
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F= 1/64, genes in common= 1/32 |
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Genetic effects of inbreeding |
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Definition
increases homozygosity (can be without a change in gene frequency) If there is dominance; aa can be inferior and inbreeding will cause a decrease in performance Alleles become 'fixed' decrease in genetic variation |
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Phenotypic effects of inbreeding |
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Definition
incerased incidence of 'throwbacks' inbreeding depression expression of deleterious recessive alleles prepotency + decrease in phenotypic variation |
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Deciline in performance. The result of non-additive gene action (dominance). Worse in low heritable traits (repoduction, survivability). |
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appears or performs like one of either parent. Most likely to result of individuals homozygous loci contain cheifly dominant alleles |
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Change in F per generation |
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Definition
1/8Nm + 1/8Nf Nm & Nf = number of males/females per generation |
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1/8nmL^2 + 1/8nfL^2 nm & nf = number of new males/females that enter population each year L = generation interval nm = Nm/L |
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appropriate change in F/yr for production animals |
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appropriate change in F/yr for endanged species |
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increases uniformity in population study inheritance pattern of recessive traits increase hybrid vigour (crossing of 2 divergen inbred lines) |
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constructing pedigrees so that animals are closely related to some 'superior' ancestor |
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increase population size increase the number of males used bring in outside genetic material consult with animal breeder |
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unrelated individuals within breed |
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animals from different breeds |
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individuals from different species |
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two inbred lines belonging to the same breed |
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two inbred lines belonging to different breeds |
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inbred males X females of outbred population |
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F1 female X one of intial breeds Maternal heterosis + 50% individual heterosis |
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backcrossing for successive generations to same intial breed |
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increases heterozygosity masks expression of deleterious recessive genes hybrid vigour/ heterosis = increased mean performance of parents |
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Advantages of outbreeding |
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Definition
add hybrid vigour breed complementarity avoid inbreeding depression mask effects of deleterious recessive alleles |
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Definition
deviation of the average of reciprocal crossbred progeny from the average of the parental breeds |
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hetrosis of fitness traits |
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heterosis of vegetative growth |
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hybrid vigour attributed to heterozygosity of the same outbred individuals upon whom the traits are measured |
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benefits of heterosis in traits accruing to the offspring of the crossbred female, rather than to the female herself. eg. individual milk production in Angus-hereford cows could be reflected as maternal hetrosis in pre-weaning growth in their progeny with Simmental bulls |
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hybrid vigour attributed to the sires, but accrues to the offspring. Eg. cross-bred bulls contribute to increased libido and higher survival rate of crossbred embryos, thereby resulting in more calves being born. |
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Genetic causes of heterosis |
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Definition
-non-additive gene action- complete dominance, over dominance, epistasis |
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Factors affecting heterosis |
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Definition
reciprocal crosses breeds involved in cross genetic and envorinmental interaction differences among traits breed complementarity |
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Basic principals of heterosis |
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Definition
max H seen in F1 H proportional to proportion of heterozygosity H 1/2 in F2 compared to F1 no further decrease in F3; hardy-weinberg equlibrium
F1 backcrossed to parent breed; H 1/2 BC1 backcrossed to breed A there will be further decrease in H Therefore it is better to keep pure breds for mating rather than backcrossing to parental breeds |
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Fixed % / specific crossing |
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Definition
2 breeds crossed, F1 sold for slaughter or other commercial use. 100% individual heterosis. |
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ABxC 50% of breed C + 25% of A&B inheritance 100% IH + maternal H |
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Definition
ABxCD 25% inheritance of each breed 100% IH + maternal and paternal H |
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Cris-crossing: systemic crossbreeding with 2 breeds maintaing 2/3 of H seen in F1 generation
Rotational crossing: 4th generation will show 6/7 H of F1 generation only sires required from pure bred matings, crossbred dams self replacing. Large variation in breed composiion between generations = marketing and management problems |
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Composit/synthetic breeds |
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Definition
express less heterosis than specific of sequential the more breeds used; the more teterosis that will be exhibited |
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Definition
Choosing the right breeds to complement each other in a cross allows the best collective performance in all traits affecting the objective of the farming enterprise |
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