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Definition
An apoenzyme + its cofactor |
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The catalytic efficiency constant for an enzymatic rxn. It is the product formation per enzyme molecule/second |
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Sources of enzymatic deficiency for a metabolic rxn |
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Definition
low concentrations of the enzyme, enzyme malfunctioning, genetic defects, nutritional deficits, toxins |
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How to calculate the rate and velocity of an enzyme |
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Definition
Keep the [enzyme] constant while manipulating other parameters of the rxn |
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Definition
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Definition
This is a transient formation of a covalent catalyst-substrate bond, often performed by Serine |
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NAD+ and CoA are examples of this |
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Definition
These are two common examples of coenzymes or cofactors |
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FAD and Biotin are two examples of this |
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Definition
These are two common examples of prosthetic groups |
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Two groups of enzymes that use metals as cofactors |
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Definition
Metal-cativated enzymes and metallo enzymes |
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Definition
Histidine, Arginine and Serine are grouped into this |
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Definition
1. Oxidation-Reduction 2. Hydrolases 3. Transferases 4. Lyases/Synthases 5. Isomerases 6. Ligases/Synthetases |
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This is the function of lyases |
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Definition
This enzyme has the general function of eliminating leaving groups on a substrate to form a double bond |
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Main difference between synthetases and synthases |
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Definition
Synthases do not utilize NTPs for their rxn while synthetases do |
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Definition
Enzymes that catalyze the transfer of functional groups containing carbon, nitrogen and phosphate |
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Term
Protein kinases and hexokinases phosphorylate these, respectively |
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Definition
-OH Groups on amino acid side chains and glucose are phosphorylated by these two enzymes |
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Expressing the rate of an enzyme |
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Definition
The amount of product (grams)/min |
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Exressing the velocity of an enzyme |
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Definition
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Definition
Coenzymes/Cofactors that only transiently associate with the enzyme |
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