Shared Flashcard Set

Details

TB
ONU med micro r-anderson
21
Microbiology
Undergraduate 2
10/24/2011

Additional Microbiology Flashcards

 


 

Cards

Term
causative agent
Definition
mycobacterium tuberculosis
Term
etiology
Definition
eubacterial pathogen, streptobacilli, acid fast, cell wall contains mycolic acid - resists drying, disinfectants, antibiotics
Term
reservoir
Definition
infected people
Term
transmission
Definition
vehicle - airborne
contact
Term
entry
Definition
respiratory route via airbourne particles or mucous droplets
Term
attachment
Definition
engulfed by alveolar macrophages after entering lungs
Term
avoid host defenses
Definition
prevents phagolysosome formation
thrives and multiples in marcophages
intracellular pathogen
Term
damage
Definition
forms ganulomas that can block alveoli and bronchioles
Term
granulomas
Definition
large cluster of macrophages surrounding infecting cells
Term
becomes active disease when...
Definition
when tubercles can no longer contain pathogens
Term
miliary TB
Definition
pathogen enters the blood stream and spreads to lungs, kidneys, brain, and bone
Term
clinical features
Definition
bad cough with bloody sputum and chest pain
weakness, fatigue, chills, night sweats, weight loss, fever, loss of appetite
Term
latent TB clinical signs
Definition
none
Term
Latent Tb test
Definition
mantoux TB skin test
Term
skin test
Definition
injects small amount of purified protein derivative tuberculin intradermally on forearm
if it swells-->TB!!
Term
diagnosis for active TB
Definition
clinical signs
acid fast bacilli in sputum
+ PCR test
Term
latent treatment
Definition
300mg isoniazid QD x6-12m
Term
active TB treatment
Definition
isoniazid, rifampin, pyrazinamide, streptomycin
Term
active treatment if prego
Definition
no pyrazinamide or streptomycin
ethambutol instead
Term
prevention
Definition
stay away from sick people
take all medicine
Term
vaccine?
Definition
yes - BCG for high rate countries and health care workers
Supporting users have an ad free experience!