Term
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Definition
ex. aspirin
tablet made by a single compression cycle
most tablets are CTs |
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Term
| SCT (Sugar coated tablet) |
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Definition
ex. tofranil
-have a sugar coating applied to them
-edges are generally rounded and have a high gloss
-very thick coating |
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Term
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Definition
(Aquacoat, LustreClear- are film coatings)
Ex. K-Tab
- thin polymeric coating applied to it
- indentations not covered up by coating |
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Term
| ECT (enteric coated tablet) |
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Definition
ex. dulcolax, arthrotec
- resist dissolving in the gastric contents
- when tablet moves to the small intestine, it should dissolve very quickly because of the different enzymes and contents |
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Term
| MCT (Multiple compressed tablet) |
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Definition
ex. ambien CR, Thyrolar, Equagesic
- layered tablets, press-coated tablets, inlays
-made by using more than one compression cycle
- these come and go from the market |
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Term
|
Definition
ex. domeboro
- used to prepare modified Burow's solution; has an antiseptic or astringent property |
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Term
| Buccal and Sublingual Tablets |
|
Definition
both are intended to be dissolved in the oral cavity and the drug is intended to absorbed by way or oral mucosa
buccal - intended to be placed in the buccal pouch (ex. striant)
sublingual - placed under the tongue; dissolved very quickly (ex. nitrostat by Parke Davis) |
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Term
|
Definition
- intended to be placed below the skin surface, either into the sub-q tissue or into the muscle
- involves some surgical technique or involves the use of an implanter
- once placed in the skin, act as a depot
- problem: sterility
- ex. testopel (testosterone); zoladex (gosrelin for breast cancer) |
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Term
|
Definition
- made using the same manufacturing process as other tablets
- undergoes disintegration, drug is released, but is obviously not intended to be absorbed
- only intended to have a local effect and be absorbed in the vaginal tract
- ovoid shaped inserted using an inserter
- ex. nystatin ; gyne-lotrimin (clotrimazole) |
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Term
|
Definition
- kid vitamins
- made with mannitol as a diluent because it is very soluble and has a somewhat sweet taste
- ex. antacids (Mylanta) |
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Term
|
Definition
- referred to as troches, pastilles
- large tablet most often disc-shaped, that contain a medicinal substance and generally a flavoring agent
- do not contain disintegrating agent
- ex. cepastat, cepacol (benzocaine), mycelex (clotrimazole) |
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Term
| Effervescent tablets (granules) |
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Definition
- granules are large particles
- undergo effervescence in water ; when the acid and the base react with water they form carbonic acid; this helps break up tablet
- acids - malic, tartaric, or citric acid, NaH2PO4
- bases - Na+ and/or K+ bicarbonates |
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Term
| Instantly disintegrating tablets |
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Definition
- prepared by compression or molding
- prepared using highly water-soluble ingredients
- solution that forms is intended for swallowing for system absorption of active ingredients
- should disintegrate/dissolve in 1 minute or less
- prepared by soft compression or lyophilization
- advantages - rapid dissolution and high C max
- know Zydis technology |
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Term
|
Definition
| no hypodermic tablets on the market today because of sterility problem |
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