Term
| What does the posterior pituitary do? |
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Definition
| Receives ADH and oxytocin from the hypothalamus, which it then transports them down the axons to terminals proximal to the capillaries in the posterior pituitary lobe |
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Term
| What does the anterior pituitary do? |
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Definition
| It receives releasing/inhibiting hormones from the hypothalamus via long portal veins which travel through the pituitary stalk to the capillaries in the anterior lobe |
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Term
| What do the short portal veins do? |
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Definition
| They connect the posterior pituitary lobe to the anterior ppituitary lobe |
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Term
| What are the hormones of the anterior pituitary? |
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Definition
1. ACTH - corticotropes
2. TSH - thyrotropes
3. LH - gonadotropes
4. FSH - gonadotropes
5. GH - somatotropes
6. Prolactin - lactotropes |
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Term
| What does somatostatin do? |
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Definition
| It inhibits TSH, GH, and PRL signaling |
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Term
| Why is it important for GH secretion to be pulsatile? |
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Definition
| It is important for maintaining the synthetic functions of GH while minimizing its insulin antagonistic actions |
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Term
| What are stimulators and Inhibitors of GH secretion? |
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Definition
Stimulators - Hypoglycemia, slow wave sleep, amino acids, puberty, stress, exercise
Inhibitors - glucose, REM sleep |
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Term
| What are the effects of GH on: liver, adipose tissue, and muscle? |
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Definition
Liver - increased gluconeogenesis, protein synthesis
Adipose tissue - increase lipolysis, decresed glucose uptake, decreased adiposity
Muscle - increased protein synthesis, decreased glucose uptake, increased muscle mass |
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