Term
|
Definition
| -promotes adjustments during stress/exercise |
|
|
Term
|
Definition
-Gq coupled
-mydriasis
-vasoconstriction
-prostate constriction |
|
|
Term
|
Definition
-*Gi coupled, many *autoreceptors
-decrease SNS outflow
-decrease aqueous humor |
|
|
Term
|
Definition
-Gs coupled
-*increase HR ionotropy(contractility)
-*increase renin (inc BP)
-inc. aqueous humor |
|
|
Term
| effects of NE and Epi depend on |
|
Definition
| which receptor predominates |
|
|
Term
|
Definition
-bronchodilation
-COMPT substrate
-inc HR/BG
-muscle contraction and efficiency
-fatty acid release
-mental alertness
-ACTH and TSH
-glycogenolysis |
|
|
Term
| adrenergic response determined by |
|
Definition
-potency of ligand at R
-proportion and density of Rs on tissue
-reflex adjustments |
|
|
Term
| *synthesis of catecholamines |
|
Definition
-from Tyrosine
-*Tyr hydrolase is rate limiting
-DBH localization determines whether NE or Epi released into synapse |
|
|
Term
| *catecholamine degradation |
|
Definition
-MAO is presynaptic
-COMPT is postsynaptic
-NOT responsible for terminating response
-exogenously administered catacholamines are substrates for COMPT |
|
|
Term
|
Definition
| primary means for terminating response |
|
|
Term
| if NE does not get back into vesicles |
|
Definition
|
|
Term
|
Definition
-Tyr enters
-dopamine,NE,serotonin transported into vesicle by VMAT
-DBH (membrane bound enzyme)
-synaptic NE is brought back into neuron by NET
-activation of a2 receptor inhibits subsequent release of NE |
|
|
Term
|
Definition
-Gs
-bronchodilation
-inc BG
-vasodilation |
|
|
Term
| both the SNS and PSNS are continuously |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| PS tone normally dominates th |
|
Definition
| heart, smooth muscle, and urinary tract organs |
|
|
Term
|
Definition
-blood vessels
-salivary glands |
|
|
Term
|
Definition
| -membrane of axon terminals,pancreas, blood platelets |
|
|
Term
|
Definition
| -heart, kidneys,adipose tissue |
|
|
Term
|
Definition
|
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Term
|
Definition
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