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Systems Exam III (L)
Carbon Dioxide Exchange and Transport
9
Medical
Graduate
04/08/2009

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Cards

Term
What is the total amount of CO2 that is excreted by a person?
Definition
288 L or 572 grams
Term

What is the partial pressure of CO2 in the tissues?

What is the partial pressure of CO2 in mixed venous blood?

What is alveolar partial pressure of CO2?

Definition

50 mmHg

46 mmHg

40 mmHg

Term
What are the 3 principle ways that CO2 is carried in the blood?
Definition

Dissolved CO2

Bicarbonate

Carbamino

Term
How much CO2 is dissolved in blood?
Definition
Each 100 ml of mixed venous blood carries 2.7 ml of CO2
Term

What is the largest carrier of CO2 in the blood?

What enzyme catalyzes the creation of bicarbonate?

What is the equation of the reaction?

Definition

Bicarbonate

Carbonic Anhydrase

CO2 + H2O <-> H2CO3 <-> HCO3- + H+

Term
T/F: The Carbon Dioxide equilibrium curve is sigmoidal in shape.
Definition
False. It is curvilinear, reflecting the lack of allosteric cooperativity. This shows how there are large content changes with small pressure changes.
Term
What is the Hamburger shift?
Definition
Movement of HCO3- out the cell comes at a cost of moving Cl- into of the cell.
Term
What is the Haldane effect?
Definition
The binding of CO2 to Hb leads to a decreased affinity of Hb for O2 and thus greater unloading. This is a physiological phenomenon that helps perfusion of tissues during CO2 production.
Term
What is the net effect of the reactions that take place at the alveolar interface?
Definition
Liberation of CO2 from bicarbonate and proteins for excretion into the lungs.
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