Term
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Definition
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Term
Is lung cancer most commo in men or women?* |
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Definition
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Term
What cancer has one of the worst prognosis'? |
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Definition
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Term
Name the type of lung cancer with a 2-4 mo survival rate (w/o tx) |
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Definition
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Term
What are the first two signs of lung cancer?* |
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Definition
cough and anorexia/weight loss |
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Term
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Definition
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Term
What are the 3 main tx of lung cancer? |
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Definition
surgery, chemotherapy, radiation |
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Term
Do lung cancer treatments incrase long term survival?* |
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Definition
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Term
What does palliative mean? |
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Definition
reducing the symptoms of a dx, improving quality of life instead of curing the dx |
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Term
What % of lung cancers involve tobacco use history?* |
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Definition
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Term
What are common environmental risks for lung cancer? |
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Definition
industrial carcinogens and air pollution |
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Term
What is the #1 cause of death in smokers? |
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Definition
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Term
What is the most common cancer in women?* |
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Definition
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Term
What is the most common cause of death in women 40-44 yo?* |
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Definition
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Term
What mutation is often seen in breast cancer? |
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Definition
BRCA 1 gene or BRCA 2 gene (tumor suppressor genes) |
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Term
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Definition
Oncogene associated with a poorer prognosis |
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Term
What are signs of breast cancer? |
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Definition
breast lump or bloody discharge |
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Term
What kind of cancers does estrogen stimulate? |
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Definition
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Term
What are two ways to image breast cancers? |
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Definition
ultrasounds or mammograms |
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Term
Where is a 70% long term remission seen?* |
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Definition
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Term
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Definition
a method of decreasing estrogen |
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Term
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Definition
hormonal therapy for breast cancer; estrogen receptor antagonist |
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Term
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Definition
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Term
What is a rare side effect for tamoxifen?* |
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Definition
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Term
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Definition
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Term
What are risk factors for breast cancer? |
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Definition
early menarche late menopause familial dx alcohol prior breast cancer |
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Term
What detects twice as many cancers as mammogram or ultrasound? |
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Definition
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Term
What can cause cancer with a BRCA + pt? |
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Definition
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Term
What is the risk of cancer if you have BRCA1? |
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Definition
breast cancer 57%; ovarian cancer 40% |
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Term
What is the risk of cancer if you have BRCA2? |
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Definition
49% breast cancer; 18% ovarian cancer |
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Term
What is the 4th most common cancer in the US? |
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Definition
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Term
What cancer has the 2nd highest mortality rate in men and 3rd highest in women? |
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Definition
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Term
What % of pt's already have metastases at diagnosis of colorectal cancer? |
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Definition
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Term
With regards to colorectal cancer, what is a late sign?* |
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Definition
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Term
Increased CEA is seen in what dx?* |
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Definition
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Term
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Definition
carcinogenci embryonic antigen |
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Term
What cancer are epidermal growth factor inhibitors used in? |
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Definition
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Term
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Definition
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Term
What is an important side effect of panitumumab?* |
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Definition
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Term
What are risk factors for colorectal cancer? |
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Definition
familial history; ulcerative colitis or Crohns, adenomatous polyps |
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Term
How can colorectal cancer be screened for?* |
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Definition
check stools for DNA indicative of cancer |
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Term
What age should colonoscopy start?* |
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Definition
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Term
What % of colorectal cancers occur in pts with no increased risk?* |
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Definition
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Term
What are 5 risk factors for liver cancer? |
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Definition
hep B heb c cirrhosis hemochromatosis alcoholism |
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Term
Is liver cancer usually primary cancer? |
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Definition
no, it has often metastasized to the liver |
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Term
What does increased AFP mean?* |
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Definition
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Term
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Definition
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Term
What is the 5th leading cause of cancer death? |
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Definition
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Term
What is the typical age of onset for pancreas cancer? |
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Definition
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Term
What increases pancreas cancer risk? |
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Definition
2x smoking risk, alcohol also increases |
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Term
what is the 5 year survival rate for pancreas cancer? |
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Definition
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Term
What are other GI cancers? |
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Definition
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Term
Where is a non-healing ulcer often seen? |
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Definition
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Term
What is the main risk for oral cancer? |
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Definition
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Term
What used to be a common cause of cancer death? |
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Definition
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Term
What cancer rate has decreased over 50% in last 30 years?* |
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Definition
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Term
What are risk factors for cervical cancer? |
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Definition
HIV infection sexual intercourse HPV* |
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Term
What age should PAP smears start at? |
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Definition
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Term
What should be the interval of PAP smears? |
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Definition
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Term
What age are PAP smears no longer necessary? |
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Definition
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Term
What HPV strains does gardasil prevent? |
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Definition
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Term
What HPV strains cause 90% of venereal warts? |
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Definition
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Term
What HPV strains cause 70% of cervical cancers? |
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Definition
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Term
What is the most common gynecologic malignancy? |
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Definition
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Term
What is the #1 symptom of uterine cancer? |
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Definition
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Term
What are common risks of uterine cancer? |
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Definition
obesity, diabetes, polycystic ovarian dx, unopposed estrogen use |
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Term
What is the most lethal gynecologic cancer? |
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Definition
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Term
Where is ovarian cancer most common? |
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Definition
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Term
What is the CA-125 marker a sign of?* |
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Definition
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Term
What is the most common male cancer?* |
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Definition
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Term
What is the median age of death in prostate cancer? |
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Definition
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Term
What is the 2nd or 3rd most common cause of death in men? |
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Definition
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Term
What are 2 complications of prostate cancer surgery?* |
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Definition
urinary incontinence; impotence |
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Term
Who has a higher risk of prostate cancer? |
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Definition
those with familial history, black |
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Term
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Definition
Prostate Specific Antigen, if this increases it is a marker for prostate cancer |
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Term
What percentage of men >70 yo have small prostate cancers during autopsy? |
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Definition
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Term
What is the peak age for testicular cancer? |
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Definition
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Term
What is the major predisposing factor for testicular cancer? |
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Definition
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Term
What cancer presents with blood in the urine? |
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Definition
bladder and kidney cancer |
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Term
What is primary vs secondary cancer? |
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Definition
primary is the origin of the cancer, secondary is metastasized cancer |
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Term
What cancer presents visual symptoms and headache?* |
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Definition
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Term
What is a highly fatal, difficult to treat cancer? |
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Definition
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Term
What is a leading cause of pediatric cancer deaths? |
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Definition
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Term
What is a rare primary cancer? |
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Definition
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Term
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Definition
Rb1 gene mutation --> absense of tumor suppressor gene |
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Term
What does the absence of Rb1 do to retinoblastoma risk? |
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Definition
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Term
What % of retinoblastoma is hereditary? |
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Definition
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