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Systemic Disease Arthritides
OPTOM 215
32
Science
Professional
10/23/2012

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Term
What are the 3 types of joints
Definition
synovial, cartilaginous, fibrous
Term
synovitis
Definition
inflammation within synovial joint capsule
Term
enthesitis
Definition
inflammation at bones attached to tendons, ligaments, joint capsules
Term
Which arthritic conditions involve the distal interphalagneal joint
Definition
Osteoarthritis, Gout
Term
What are ocular effects of anti-malarials hydroxychloroquine (Plaquenil) for rheumatoid arthritis
Definition
Retinopathy , corneal deposits, EOM weakness
Term
ESR
Definition
Erythrocyte Sedementation rate - elevated sed rate = inflammation because more fibrinogen makes RBCs stick together
Term
RF
Definition
Serum Rheumatoid Factor - an autoantibody RF to IgG.
Term
ANA
Definition
Antinuclear Antibody - looks for Ab's that attack WBC nuclei (autoimmune disease)
Term
HLA B27
Definition
Human Leukocyte Antigen typing reflects histocompatibility and immune responsiveness. Strong association in ankylosing spondylitis
Term
Erythema Migrans
Definition
flat or slightly raised red rash - may expand with central clearing - bulls eye rash found in Stage 1 of Lyme Disease
Term
myalgia
Definition
muscle ache
Term
arthralgia
Definition
joint ache
Term
What Septic Arthritis also features symptoms of Bell's Palsy (ectropion), ocular inflammation, neurologic and skin effects?
Definition
Arthritis caused by stage 3 Lyme Disease
Term
This type of arthritis affects multpile, symmetrical, and synovial joints - often hand, knees, ankles, toes
Definition
Rheumatoid Arthritis
Term
Which type of arthritis may feature the development of episcleritis and or bulbar nodules
Definition
Rheumatoid Arthritis
Term
Use of what drug (for Rheumatoid Arthritis) may cause maculopathy (bull's eye), VA loss, field defects, photopsia, photophobia, and nyctalopia?
Definition
Chloroquine - 2nd line drug, usually an antimalarial.

Nyctalopia = night blindness
Term
What are the 3 types of juvenile arthritis
Definition
1) Pauciarticular/Oligoarticular
2) Polyarticular
3) Systemic
Term
Which type of juvenile Arthritis has the highest risk of uveitis?
Definition
Pauciarticular/Oligoarticular JA.
Term
Which type of autoimmune arthritis shows Reynauds Phenomenon
Definition
SLE systemic lupus erythematosus
Term
What are the most common SLE ocular problems
Definition
1) Keratoconjunctivitis sicca (25%)
2) SLE retinopaty (AFTER KCS) , cotton wool spots and Roth spots
Term
What are the earliest SLE ocular problems?
Definition
scleritis, episcleritis
Term
What are the most devastating ocular problems with SLE?
Definition
Severe Retinal Vasculitis 6/60 VA (50%)
Term
Chronic dysfunction of exocrine glands
Definition
Sjogren's Syndrome
Term
xerostomia
Definition
dry mouth - as in Sjorgen's syndrome
Term
what is the most common joint disorder
Definition
Osteoarthritis (A degenerative arthritis)
Term
What is a crystal deposition arthritis?
Definition
Metabolic Arthritis - Gout
Term
What is an exmaple of a metabolic arthritis
Definition
gout
Term
What is an example of a degenerative arthritis
Definition
Osteoarthritis
Term
How should you go about treating gout
Definition
1st the arthritis, 2nd if at all the hyperuremia
Term
What are 3 Spondyloarthropathies
Definition
Ankylosing Spondylitis, Reactive Arthritis, Psoriatic Arthritis
Term
What is the clinical tetrad of Reactive Arthritis?
Definition
Urethritis, Mucocutaneous Lesions, Aseptic Arthritis, Conjunctivitis/or Uveitis
Term
What class or arthritis diseases features uveitis and lower back pain?
Definition
Spondyloarthropathies
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