the Neurotransmitters

and their receptors

Epinephrine: B1, B2, a1, a2

Norepinephrine: B1, a, limited B2

Dopamine: D --> B1 --> a

Isopreterenol: B1, B2

1. anaphylactic shock

2. shock by spinal anesthesia

3. asthma

4. cardiac arrest

5. vasoconstriction w/ local anesthetics 

shock w/ Epi/NE

(dilates renal bv's to prevent kidney's from shutting down)

1. asthma (b/c broncho-relaxation)

2. cardiac arrest

Selective B2 Agonists:

names and indications

1. metaproterenol

2. albuterol

3. salmeterol

4. terbutaline 

Indications: 1. Asthma, 2. delay labor 

Selective α Agonists:

names and indications

1. phenylephrine (topical/oral)

2. oxymetazoline (topical)

Indications: decongestion (nasal, ocular) 

Indirect Acting Sympathomimetics:

names and indications

1. amphetamine (Adderall)

2. methylphenidate (Ritalin)

Indications: ADHD, Narcolepsy 

Mixed Acting Sympathomimetics:

names and indications

1. ephedrine (crosses BBB)

2. pseudo-ephedrine (less BBB crossing)

Indications: decongestants 

Reuptake Inhibitors:

names and indications

1. cocaine

2. tricyclic antidepressants

Indications: 1. increase in entire sympathetic system activity; 2. a wicked good time, apparently

a Blockers:

names and indications

"--azosin"

1. Prazosin

2. Terazosin

3. Doxazosin

Indications: 1. HTN; 2. enlarged prostate; 

3. congestive heart failure 

Selective a1 Blocker:

name and indication

tamsulosin

treat enlarged prostate

5a Reductase Inhibitor:

name and indication

Finasteride

Treat enlarged prostate

**not an adrenergic drug**

B Blockers:

names and indications

"--lol"

 Non Selective:          Selective (B1)

1. proparanol           1. atenolol

     2. timolol               2. metoprolol

Indication: 1. HTN; 2. arrhythmias; 3. angina; 4. congestive heart failure; 5. panic attacks; 6. stage fright; 7. tremors; 8. Glaucoma

Neuronal Blockers:

names and indications

1. Clonidine

2. Reserpine

Indications: HTN