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Swedish Paramedicine
Field Drugs Classes and Actions
42
Pharmacology
Professional
06/13/2011

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Cards

Term
Promethazine (Phenergan)
Definition
Class: Phenothiazine
Action: (1) Takes away the sensation to vomit by antagonizing H1 receptors
(2) possible depressor of chemoreceptor trigger zone in medulla
Term
Verapamil (Isoptin)
Definition
Class: Non DHP calcium channel blocker.
Action: (1) Inhibits calcium ion influx through slow channels into cardiac and arterial smooth muscle.
(2) decreases and slows SA and AV node
Term
Procainamide (Pronestyl)
Definition
Class: 1a ventricular antiarrythmic
Action: (1) increases the duration of the refractory period
(2) Depresses the excitability of the myocardium to electrical stimulation, decreases conduction in the atria, ventricles, and His-Purkinje system
Term
Cardizem (Diltiazem),
Definition
Class: Non-DHP Calcium channel blocker
Action: (1)slows conduction, at AV node
(2) causes coronary and peripheral vasodilation
Term
Dextrose 50%
Definition
Class: Carbohydrate
Action: Increased blood glucose by providing free sugar quickly released into the blood stream
Term
Amiodarone (Cordarone)
Definition
Class: Class III antidysrhythmic (K+ blockade)
Action: (1) Prolongs the duration of the action potential and effective refractory period
(2) Includes noncompetitive andrenoreceptor and calcium channel blocker activity
Term
Vecuronium Bromide (Norcuran)
Definition
Class: Non depolarizing paralytic
Action: Inhibits neuromuscular transmission by competitive binding with acetylcholine to motor receptors.
Term
Succinylcholine (Anectine)
Definition
Class: depolarizing neuromuscular blocker
Action (1) Works on skeletal muscle, blocks voluntary muscle
Term
Ipratropium (Atrovent)
Definition
Class: Anticholinergic
Action: (1) Blocks acetylcholine at receptor sites on bronchial smooth muscle
Term
Metoprolol
Definition
Class: selective Beta 1 blocker
Action: Blocks beta 1 receptors causing decrease in HR, cardiac output and BP
Term
Bethine (Terbutaline)
Definition
Class: Beta 2 agonist
Action: Causes effects of beta 2, has some effects on beta 1
Term
Atropine Sulfate
Definition
Class: Anticholinergic
Action: (1) Competes with acetylcholine receptor sites at SA & AV nodes.
(2) Increases heart rate by increasing conduction at SA and AV nodes
(3) Inhibits secretions by decreasing PNS effects on bronchial, salivary, sweat and GI glands
Term
Vasopressin (Pitressin)
Definition
Class: Hormone
Action: vasocontricts
Term
Thiamine
Definition
Class: Vitamin (B1)
Action: necessary for carbohydrate metabolism
Term
Metoclopramide (reglan)
Definition
Class: Antiemetic/Sodium Channel blocker
Action: (1) elevates the chemoreceptor trigger zone threshold.
(2) Sensitizes GI smooth muscle to the effects of acetylcholine by direct action
Term
Racemic Epinephrine
Definition
Class: Catecholamine, Sympathomimetic
Action: (1) Stimulates alpha and beta adrenoreceptors with a slight preference on beta 2.
(2) causes bronchodilation and a decrease in mucus secretion
Term
Diazepam (Valium)
Definition
Class: Benzodiazepine
Action: (1) Increases the effect of gamma aminobutyvic acid.
(2) Acts on the CNS to raise the seizure threshold in the motor cortex
(3) causes amnesia
Term
Lorazepam (Ativan)
Definition
Class: Benzodiazopine
Action: (1) Enhances the effects of gamma aminobutyric acid
(2) effects: anxiolytic, sedative, hypnotic, and skeletal muscle relaxant
Term
Midazolam (Versed)
Definition
Class: Benzodiazepine
Action: (1) Intensifies activity of gamma aminobenzoic acid
(2) Calms, relaxes skeletal muscles, and in high doses causes sleep
Term
Mannitol (Osmitrol)
Definition
Class: osmotic diuretic
Action: Causes a fluid shift in the brain, pulls the fluid out of the vascular space and causes it to be urinated off
Term
Albuterol (proventil, ventolin)
Definition
Sympathomimetic, Selective beta 2 agonist
Action: (1) Causes the beta 2 adrenergic receptors to relax smooth muscle
(2) Bronchodilation, relieves bronchospasms, reduces airway resistance
Term
Sodium Bicarbonate
Definition
Class: Electrolyte
Action: Potent systemic antacid, raises the pH of blood by buffering excess hydrogen ions
Term
Methylprednisone Sodium (solumedrol)
Definition
Class: Steroid
Action: decreases the inflammatory response
Term
Aspirin (ASA, acetylsalicylic acid)
Definition
Class: antiplatelet, salicylate
Action: Interrupts thromboxone A2
(2) Inhibits prostaglandins
Term
Zofran (Odansetron)
Definition
Class: Antiemetic
Action: Reduces the sensation to vomit (action not fully characterized)
Term
Naloxone (Narcan)
Definition
Class: Opioid antagonist
Action: Reverses effects of opioid overdose by occupying opiate receptor sites
Term
Diphenhydramine (benadryl)
Definition
Class: Antihystamine (H1)
Action: Binds to histamine receptor sites, suppressing histamine induced allergic reactions
Term
Lidocaine (Xylocaine)
Definition
Class: Class 1b
Action: Sodium Channel Blocker
(2) Decreases phase 0 diastolic depolarization
Term
Adenosine (Adenocard)
Definition
Class: Endogenous nucleoside
Action: Slows electrical conduction at the AV node
Term
Dopamine (Intropin)
Definition
Class: Sympathomimetic/inotrope
Action: at low/medium doses beta effects, mostly inotropic
(2) medium to high doses alpha and beta effects
(3) at high doses alpha effects
Term
Epinephrine 1:10,000 (Adrenaline), class and action are the same for 1:1,000
Definition
Class: sympathomimetic
Action: Bronchodilation, Vasoconstriction
(2) On the heart: increased HR, contractility, AV conduction, automaticity
Term
Etomidate (Amidate)
Definition
Class: Non Benzo sedative hypnotic
Action: Exact measure is unknown but appears to have gamma aminobutyia effects
Term
Fentanyl (Sublimaze)
Definition
Class: synthetic opioid analgesic
Action: Combines with receptor in the brain to produce analgesic effects
Term
Flumazenil (Romazicon)
Definition
Class: Benzodiazepine antidote
Action: decreases the effect of gamma aminobutyric acid.
Term
Furosemide (lasix)
Definition
Class: loop diuretic
Action: inhibits sodium reabsorption primarily in the loop of henle but also in proximal and distal renal tubules
Term
Haloperidol (Haldol)
Definition
Class: similar effects to phenothiazine
Action: Binds to receptor sites in the brain associated with mood and behavior
(2) strong antiemetic effects and impairs central thermoregulation
Term
Glucagon
Definition
Class: Hormone
Action: Increases blood sugar by concerting glycogen stored in the liver to glucose
Term
Magnesium Sulfate
Definition
Class: Electrolyte
Action: CNS depressant, depressant of smooth, cardiac and skeletal muscle
Term
Morphine Sulfate
Definition
Class: opioid analgesic
Action: CNS depressant acting on opiate receptors in the brain
(2) potent pain reliever and sedative
(3) relaxes respiratory effort
Term
Nitroglycerine (Nitrostat)
Definition
Class: Nitrate
Action: relaxes systemic venous & arterial vessels causing vasodilation
(2) Dilate coronary arteries
Term
Opthaine
Definition
Class: Topical opthalmic
Action: blocks the pain receptors in the eye
Term
Oxytocin (Pitocin)
Definition
Class: Hormone
Action: stimulates uterine contractions
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