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Surg Objectives Block 15
KYCOM Block 15
271
Medical
Graduate
04/11/2014

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Cards

Term
what is a vericocele, where is the location
Definition
dilation of pampinform plexus of testicle
more common on left becuse the vessel goes all the way up to the renal vein
(if on right is more likley a tumor)
90% unilateral
Term
how are varicoceles graded
Definition
grade I: palpable with valsalva (feels like bag of worms)

grade II: palpable w/o valsalva

grade III: visible
Term
how do you treat a bile duct injury caused by laproscopic cholecystectomy
Definition
primary repair with T tube and drainage
Term
how is GERD diagnosed
Definition
elevated DeMeester score on Bravo Probe or proved reflux esophagitis
Term
what are the 7 testicular neoplasms and their prevalence
Definition
seminoma 35%
embryonal cell 20%
teratoma 5%
mixed cell 40%
lymphoma
leukemia
metastic
Term
what is the most common testicle tumor under 50yo
Definition
mixed cell: teratoma and embryoma
Term
what age does seminoma show up
Definition
40s
Term
what age does embryonal cell testicular neoplasm show up
Definition
25-35
Term
what age does teratoma show up
Definition
10-30
Term
what is the most common testicular tumor >50yo
Definition
lymphoma
Term
who gets testicular leukemia most often
Definition
kids relapsing with ALL
Term
3 cancers that metastasize to the testicle
Definition
prostate, lung, GI
Term
origin of autonomic errection center
Definition
S2-4 and T12-L2
Term
what are the 5 nerve centers that innervate the penis
Definition
autonomic errection center
cavernous nerves
somatic motor nerves
parasympathetic tumescence
sympathetic detumencence
Term
origin of the somatic motor nerves of the penis
Definition
S2-S4
Term
male sexual dysfunction prevalence
Definition
20 million men in the US
Term
4 types of male sexual dysfunction
Definition
impotence
premature ejaculation
retrograde ejaculation
retarded ejaculation
Term
2 activities less exerting than intercourse and 2 that are more, and 1 that is same
Definition
less: light housework, walking
same: gardening
more: golf, lifting
Term
how can you tell if sexual dysfunction is a psych issue or physiological
Definition
if they get nocturnal penile tumescence (errection) its psych
Term
contraindications to viagra 7
Definition
nitrates
recent MI, stroke, arrhythim in 6mo
resting BP <90/50
unstable angina
retinitis pigmentosa
Term
what is nephrolithiasis
Definition
stone in collecting tubule that passes into calyces, renal pelvis, ureter due to supersaturated urine
Term
what is the number one cause of nephrolithiasis
Definition
pop
Term
what is the 3rd most common affliction of urinary tract
Definition
nephrolithiasis
240000-720000 have kidney stone each year
Term
what is the most important urinary stone type, how is it made
Definition
oxalate/calcium caliculi: build up due to phosphoric acid in pop
supersaturation of urine with Ca and oxylate
stones form on tip of renal papillae as yellow plaque
Term
risk factors for calcium caliculi 4
Definition
low urine volume
hot temperature
increased Ca absorption from SI
hyperparathyroidism
Term
absorptive hypercalcuric nephrolithiasis: cause and TX
Definition
increased Ca absorption in SI increases urinary Ca
TX limit Ca intake
Term
what are the only urinary stones that can be dissolved, how
Definition
uric acid (non calcium caliculi)
stone forms from low urinary pH so raising pH >6 (alkaline therapy) cause dissolution
Term
if someone has non localized flank pain where is their urinary stone
Definition
caliceal caliculi obstructs infundibulum

small caliculi are non obstructive but can still be symptomatic
Term
if someone has localzied flank pain where is their urinary stone
Definition
renal pelvis
Term
if someone has sharp intermittent flank pain where is their urinary stone
Definition
proximal ureter
Term
if someone has pain along inguinal canal to groin where is their urinary stone
Definition
distal ureter
Term
if someone has frequency, urgerncy, retention where is their urinary stone
Definition
UVJ
Term
signs of pyrlonephritis
Definition
ALL 3 needed
flank pain
fever and chills
bacteria
Term
3 types of work up for UTI which is the best, why
Definition
suprapubic aspiration: most accurate

straight cathed specimen: good results, best choice for most

bagged specimen: poor results, little benifit, unneeded expensive work up
Term
specific signs of UTI 4
Definition
fever, irritability, dysuria, suprapubic pain
Term
non-specific signs of UTI 4
Definition
poor feeding
weight loss
vomiting
diarrhea
Term
signs of UTI in infant 2
Definition
fever and irritability with unidentified source
Term
5 malignant tumors of the kidney, which is most common
Definition
renal cell carcinoma 85%
metastic
lymphoma
onchocytoma
wilms
Term
3 causes of bladder carcinoma, which is most common
Definition
smoking #1 (just like kidney cancer)
occupational: dye, auto parts
infection/virus
Term
what is a normal PSA
Definition
0-4
Term
clinical findings of prostate cancer 7
Definition
PSA >4 30% chance cancer
PSA rise of >1 per year
prostate nodule
asymptomatic
biopsy positive
gleason score positive
bone scan positive (at gleason 8-10 and PSA>10, later in disease)
Term
treatment of stress urinary incontinance 7
Definition
behavorial modification
pelvic floor exercises
medications
devices
bulking agents
surgery
artificial urinary sphincter
Term
2 surgeries of stress urinary incontinence
Definition
suspension: reinforce/strengthen existing structures

sling: use new structure to make support system (synthetic mesh can grow into urethre watch out)
Term
treatment of urge incontinence 3
Definition
behavior modification
medication
pelvic floor exercises
Term
most common obstructive urethral lesion in infants and newborns
Definition
posterior urethral valve
Term
posterior urethral valve: cause, location, appearance
Definition
congenital
distal prostetic urethra
mucosal folds that look like membranes
Term
posterior urethral valve: sighs
Definition
obstruction (mild to severe)
palpable bladder distension
CR and BUN elevation (indicators of renal failure
Term
hypospadius cause
Definition
urethral meatus on ventral side due to incomplete fusion of urethral folds often due to estrogen or progesterone given in pregnancy
causes hooded foreskin
Term
classifications of hypospadius 8 (in order from pepuce to testicle), which is most common
Definition
glandular 50% LOTS!
subcoronarl LOTS!
distal penile
midshaft
proximal penile
penoscrotal
scrotal
perineal
Term
which hypospadius are considered anterior
Definition
glanular
subcoronal
Term
which hypospadius are considered middle
Definition
distal penile
midshaft
proximal penile
Term
which hypospadius are considered posterior
Definition
penoscrotal
scrotal
perineal
Term
interstitial cystitis: who gets it
Definition
middle aged women
Term
interstitial cystitis: morphological changes 4
Definition
bladder fibrosis
capacity 60mL
punctuate hemorrhagic area
hunners ulcer
Term
interstitial cystitis: 3 symptoms
Definition
suprapubic pain
severe frequency
relieved upon voiding
Term
interstitial cystitis: why is there pain
Definition
when bladder fills it pushes on fibros
Term
interstitial cystitis; TX 3
Definition
oversistension
DMSO irrigation
elmiron oral
Term
what is enuresis
Definition
bedwetting >3yo due to delayed maturation of nervous system
Term
ages common for enuresis and prevalence
Definition
6yo 10%
14yo 5%
most gain control at 10yo
Term
treatment of enuresis 5
Definition
fluid restriction
voiding before bed
alarm clock
imipramine at HS
DDAVP andiduiretic
Term
symptoms of BPH 6
Definition
nocturia
uregency
frequency
UTI
incomplete bladder emptying (urinary retention)
overflow incontinence
Term
complications of BPH 5
Definition
bladder calciuli
UTI
renal failure
hematuria
loss of bladder function
Term
what is the DOC for BPH and the MOA
Definition
a-adrenergic receptor antagonists
block a1 an a1 receptors
Term
where are a1 recetptors targeted in BPH treatment 2, how does antagonism cause effect
Definition
prostate capsule and bladder neck
mediate muscle tone
Term
where are a2 recetptors targeted in BPH treatment, how does antagonism cause effect 3
Definition
outside urinary tract
cause SE: hypotension, dizziness, nasal secretion
Term
2 a1 antagonists
Definition
doxazosin
terazosin
Term
what BPH drug has the least retrograde ejaculation
Definition
uroselective a1 antagonist alfuzosin
Term
when treating for BPH why is the PSA not accurate marker of progress
Definition
because it will decrease by half due to medicine
Term
what is the total body water of a premature infant, full term neonate, and averge adult
Definition
preterm; 90%
full term: 80%
adult: 60%
Term
what percent of total body weight is total body water, intracellular fluid, extracellular fluid, plasma
Definition
TBW 60%
ICF 40%
ECF 20%
plasma 4.3%
Term
what is the intracellular fluid composed of
Definition
red cell volume
Term
what is the extracellular fluid composed of
Definition
interstitial fluid 75% ECF
plasma volume 25% ECF
Term
what are the 4 regions of the urethra
Definition
penile or spongy
membranous
pre-prostatic
prostatic
Term
explain the 4-2-1 rule for fluid replacement
Definition
4mL fluid/kg for 1st 10kg
2mL fluid/kg for 2nd 10kg
1mL fluid/kg for rest
Term
extrinsic clotting pathway: what triggers it, explain the pathway
Definition
tissue factor released by trauma converts VII > VIIa
VIIa converts X > Xa
Xa converts prothrombin > thrombin
thronbin converts fibrinogen to fibrin
Term
how is the extrinsic clotting pathway monitored, what is normal
Definition
PT normal 14sec
INR normal 1.0
Term
what drug affects the extrinsic clotting pathway and how
Definition
warfarin stops vitamin K dependent clotting factors (II, IV, IX, X, protein C, protein S)
Term
how is warfarin activity monitored
Definition
ptolonges PT
Term
warfarin antidote
Definition
vitamine K SQ
(slow)
Term
indications for warfarin treatment 3
Definition
atrial fibrillation
DVT/PE
mechanical cardiac valve
Term
blood transfusion related injuries 6
Definition
ABO incompatability
transfusion related acute lung injury
sepsis from bacterial infection
massive transfusion complications
transfusion related circulatory overload
DIC - consumptive coagulopathy/hypercoaguability
Term
universal blood donor type
Definition
O-
Term
ABO incontability: timing, what to monitor for 3
Definition
occurs immediatly up to 7d post transfusion

monitor urine output, K levels, coagulation (possible DIC)
Term
transfusion related acute lung injury: caue, timing, appearance and clinical signs
Definition
frequent with PRBC but can occur with any blood product
usually begins 6h after transfusion
clinical signs like ARDS
causes noncardiogenic pulmonary edema
Term
transfusion related acute lung injury: treatment and prognosis
Definition
supportive treatment
8% mortality
Term
what is transfusion related circulatory overload
Definition
too much fluid too fast and it leaks out of orifaces (esp lungs)
Term
causes of DIC 4
Definition
sepsis, amniotic fluid embolism, trauma, transfusion
Term
TX DIC
Definition
anticoagulation (even though clotting factors exausted)
Term
100kg male scheduled for CABG. calculate his blood volume
Definition
100kg x 7% = 7L
100kg x 70mL/kg = 7000mL = 7L
Term
50kg female patient that has no NPO for elective right knee arthroscopy. calculate TBW, ICF, ECF, blood volume
Definition
TBW 60% 30L
ICF 40% 20L
ECF 20% 10L
BV 7% 3.5L
Term
145lb female weight kg and hourly maintenance fluids
Definition
145/2.2 = kg
then follow 4-2-1 rule
Term
100kg male in exploratory laporotomy for 4h. NPO for 18h, EBL 100mL, loss 10mL/kg/hr. what are hourly maintenance fluids, fluids needed to replace EBL, fluids needed to replace insensible losses, total fluid while in OR
Definition
140ml/h
1500ml crystalloid or 500ml colloid
4L
8.5L
Term
what is insensible evaporative loss
Definition
up to 20ml/kg/hr for large open abdominal surgery
Term
EBL replacement
Definition
blood replacement
3mL crystalloids per 1mL EBL
colloid 1mL per 1mL EBL
Term
5 considerations for maintenance fluids
Definition
NOP status
maintenance fluid
blood loss EBL
evaporative loss
insensible loss
Term
DDX of RUQ pain 30
Definition
cholelithiasis
cholecystitis
cholangitis
cirrhosis
hepatitis
fritz hugh curtis syndrome
leukemia
GERD
gastritis
PUD
esophagitis
gastroparesis
gastric outlet obstruction
gastric cancer
esophageal cancer
pneumonia
pulmonary emboli
bronchiectasis
nephrolithiasis
pyelonephritis
hydronephrosis
renal cancer
DKA
pancreatitis
pancreatitc cancer
addisons crisis
adrenal TB
lymphoma
budd chiari
CHF
Term
what areas can GERD causes pain
Definition
epigastric
RUQ
nausea and emesis
Term
DDX LLQ pain 30
Definition
diverticulitis
gastroenteritis
IBS
acute appendicitis
small bowel obst
meckel diverticulitis
mesenteric adenitis
IBD
large bowel obst
constipation
colonic volvulus
food poisoning
UTI
cystitis
urosepsis
uremia
nephrolithiasis
PID
uterine fibroid
ectopic pregnancy
adenomyositis
endometrosis
ovarian cystic disease
pelvic congestion syndrome
hernia
muscle strain
muscle spasm
myositis
abnormal aortic anrueysm
aortic dissection
Term
when do most congenital abnormalities of the limbs happen and why
Definition
4-8wk because this is major time of limb growtn in embryogenesis between limb development and hand plate development
Term
syndactyly: definition
Definition
interdigital cleft does not regress so fingers remain attached
Term
syndactyly: types and the difference
Definition
simple: some regression, some finger differentation

complete: no regression, no finger differentation
Term
bradysyndactyly definition
Definition
small fingers without regression of web
Term
poland syndrome definition
Definition
absence of pectoral muscles, subclavicular depression, brachysyndactyly
Term
what is the biggest worry in a minor finger laceration
Definition
digital arteries are lateral to digital nerve
if small laceration to digital artery causes pulsitile bleed means 90% chance cut digital artery too
Term
what is the most common injury of the hand and what diagnosis is it often associated with
Definition
nail bed laceration: associated with distal phalynx (tuft) fracture
Term
what layer of skin has nerves and vessels
Definition
subcutaneous
Term
where on the hand are we more worried about digital nerve and artery laceration
Definition
more proximal than distal
Term
what 2 flexor tendons are on all fingers but thumb
Definition
flexor digitorum superificialis
flexor digitorum profundus
Term
what 1 tendon is on the thumb
Definition
flexor pollicus longus
Term
what injury is worse than fracture in finger
Definition
flexor tendon injury because they dont heal fast and scar tissue causes stuffness
Term
tx flexor tenon injury
Definition
refer to hand surgeon ASAP, requres surgery within 2wks because tendons snap back and shorten too much for repair
Term
which joint does flexor pollucus longus move if you isolate
Definition
PIP
Term
what joint does flexor digitorum superificialis move if you isolate
Definition
metacarpal carpal
Term
cause of jersey finger
Definition
football player grabs jersey while other player is running and leads to avulsion of flexor digitorum profundus
DIP was forced in active flexion
can sometimes take some bone with it
Term
jersey finger treatment
Definition
needs to be repaired within a week or tendon could regress too far (better prognosis if it ripped off bone because it cannot regress as much)
Term
what is most common closed tendon injury of finger
Definition
extensor tendon injury (mallet finger)
Term
mallet finger: cause
Definition
tucking in sheet, ball it tip of finger
extensor tendon at DIP is trying to stay extended but it is forced to bend
Term
mallet finger treatment
Definition
not emergency, extensor tendon connected by junction tendon, keep shaped and form scar tissue on straight finger

take to surgery if fits indications
Term
indications of mallet finger surgery
Definition
avulsion fracture or sublexating
avulsion >30% joint involved
inability to get passive full extension
SWAN NECK DEFORMITY: hypertextension of PIP and flexion of DIP
Term
what is the most common finger dislocation
Definition
coach's finger/jammed finger/PIP joint
Term
coach's finger: appearance, diagnosis
Definition
volar plate injury (soft tissue) or avulsion fracture of middle phalanx due to DORSAL DISLOCATION, ALWAYS REQUEST 3 X-RAY VIEWS
Term
what is the most common metacarpal bone fracture
Definition
boxer's fracture
Term
pathogenesis of boxers fracture
Definition
distal fragment displaces at volar angle due to action of interosseous muscle
neck of 5th metacarpal with dorsal angulation
can cause rotation, cross over, or hyperextension deformity
Term
TX boxers fracture
Definition
up to 40 deg angulation can have reduction (jhass reduction)

but greater needs fixation with wires
Term
explain jhass reduction maneuver
Definition
make fist and pushh on head to proximal phalangeal joint

it pushes distal fracture segment back and other hand puts pressure on shaft of metacarpal

need to do ASAP weeks later wont work, follow with ulnar gutter splint
Term
carpal tunnel pathogenesis
Definition
compression neuropathy of median nerve due to repeated movment, wrist flexion, CONGENITAL NARROW TUNNEL, trauma, fluid, pregnancy, RA, cyst
Term
felon or whitlow: define
Definition
infection causes fibrous bands that attach skin to bone (so when you hold stuff skin dosent move)

if not relieved causes necrosis, will need surgery and drainage, antibiotics not enough
Term
infectious pyogenic flexor tenosynovitis signs 4
Definition
kanavels signs:
finger partially flexed
pain with passive extension
flusiform or diffuse swelling on affected finger (sausage finger)
tenderness over course of affected tendon (even when not visible inflammed)
Term
what is the most common joint of osteoarthritis in the hand
Definition
first carpometacarpal
Term
what is the most common autoimmune disorder of the upper extremity
Definition
RA
Term
what are the most common hand tumors
Definition
benign ganglion cyst or benign lump
Term
signs of glomus tumor 5
Definition
intermittent severe pain
point tenderness
cold intolerance
sublingual bluish discoloration on nail ridge
single or multiple lesions
Term
what is the most common malignant tumor of hand and nailbed
Definition
SCC
Term
SCC hand and nailbed: prognosis, age, signs
Definition
agressive local infiltration 5-28% metastasis
60yo

subungal or perionchial wart like tumor, large ulceration, exophytic lesion
Term
gout cause
Definition
percipitation of monosodium urate crystals in joint or tendon sheath causes acute inflammatory reaction, swelling, erythema, pain
Term
gouty tensosynovitis: signs
Definition
presents lik arthritis, infection, RA, neoplasm, digital triggering, CTS, tendon rupture
Term
signs of gout
Definition
gouty tensonobitis
gout trophy
hyperuricemia
white chalk seeps through skin laceration
Term
gouty trophy appearance
Definition
skin compormise, contracture, ulceration, tendon rupture
Term
TX gout
Definition
NSAID DOC FOR TX OF FLARE
chlochicine and NSAID for flare
surgical debridement
Term
what is the most common source of emboli to the heart
Definition
subclavian artery
Term
burger disease cause
Definition
ischemia and necrosis in smoker (thromboangitis obliterans)
Term
hypodermal syndrome: cause
Definition
occlusion of ulnar artery in manual workers
Term
diagnosis of vascular diseases of the hand and arm
Definition
always check heart
allens test: make fist, occlut both arteries, release one at a time (should fill in <5sec)
Term
signs of acute vascular disease of upper extremity
Definition
acute finger tip necrosis
often in ICU patient
Term
definition of abdominal/visceral pain
Definition
sudden onset pain, tenderness, that will not go away on its own and usually needs emergency surgery
Term
how can you tell there has been a GI perforation 3
Definition
air on x-ray under diaphragm
rigid abdomen
emergent
Term
4 causes of GI perforation
Definition
gastrointestinal ulcer
gastrointestinal cancer
boerhaave syndrome
perforated diverticulum
Term
cholelithiasis: risk factors 8
Definition
more with age
women
native american
obesity
multiparity
rapid weight loss
oral contraceptives
TPN chrons
Term
cholelithias types
Definition
cholesterol
pigmented 20%
mixed 75%
Term
2 types of pigmented cholelithiasis and where they are located
Definition
black: from sterile bile within gallbladder
brown: from infected bile duct, soft
Term
cause of black cholelithiasis
Definition
cirrhosis
hemolytic disease
Term
cause of brown cholelithiasis
Definition
infected
Term
what labs indicate cholelithiasis
Definition
ALP+GGT > AST+ALT
ALP is made in biliary epithelium and bone
GGT if elevated with ALP means biliary not bone

AST+ALT are made in hepatocytes and will be increased but not as much
Term
6 ways to diagnose cholelithiasis
Definition
x-ray
ultrasound
hida scan
CT scan
MCRP
ECRP
Term
effectiveness of x-ray in cholelithiasis diagnosis
Definition
only 10% of gallstones have enough Ca to see
Term
effectiveness of ultrasound in cholelithiasis diagnosis
Definition
study of choice
95% sensitive and specific
reveals stones from 3mm
limited in aveluating choledocholithiasis
Term
MOA and interpertation of HIDA scan in cholelithiasis diagnosis
Definition
inject techenium labeled imidodiacetic acid which goes into hepatocyte then is excreted in bile then duodenum

if GB does not fill in 1h (normal 30min) but the CBD and duodenum then it is acute cholecystitis

if marker shows in extra biliary location pt has biliary tree injury
Term
effectiveness of CT scan in cholelithiasis diagnosis
Definition
low sensitivity for cholithiasis
expensive
detect level and etiology of biliary obstruction
Term
effectiveness of MCRP in cholelithiasis diagnosis
Definition
expensive, non-invasive
evaluate for choledocholithiasis!
Term
MOA of ECRP in cholelithiasis diagnosis
Definition
invasive, needs anesthetic
ampulla of vater is accessed endoscopically
contrast injected into biliary tree
stones if identified removed
biopsies and brushing sobtained
Term
tx of asymptomatic cholelithiasis
Definition
if stones found incidently 1-2% pt will get symptoms so prophylactic cholecystectomy not needed, wait until symptoms develop to do surgery
Term
signs of chronic cholecystitis
Definition
biliary colic
no murphys sign (peritoneal irritation)
no infection: normal temp, WBC, liver function tests
Term
preferred diagnosis method of chronic cholecystitis
Definition
ultrasound
Term
what is biliary colic
Definition
severe constant pain in RUQ that radiates into back
brought by spicy/fatty food, lasts hours, then resolves

due to contraction of GP against stone in CYSTIC DUCT
Term
cause of acute cholecystitis
Definition
sustained block of cystic duct causes progressive peritonitis
Term
sighs of acute cholecystitis 7
Definition
Psoas sign; epigastric RUQ pain radiating to back
nausea, emesis, fever, gaurding, rebound tenderness
murphys sign; arrested inspiration qith RUQ pressure due to peritoneal irritation
Term
acute cholecystitis lab signs 5
Definition
high leukocytes, left shift
elevated bilirubin, AST, ALT, ALP
Term
ultrasound findings in acute cholecystitis 3
Definition
GB wall thick >3mm, pericholecystic fluid, distension
Term
HIDA scan findings in acute cholecyststis
Definition
GB not visualized until 4h
Term
treatment of acute cholecystitis
Definition
symptoms <3d: antibioics, laproscopic cholecystectomy

symptoms >3d: antibiotics, analgesic, schedule for interval cholecystectomy in 4-6wk
(decreases complications)
Term
what is choledocholithiasis and cholangitis
Definition
infection of the common bile duct
Term
symptoms choledocholithiasis 2
Definition
intermittent jaundice
episodes of biliary colic
Term
symptoms acute cholangitis 4
Definition
charcots triad: RUQ pain, jaundice, fever
reynolds pentad later: mantal status change and hemodynamic instability
Term
how is choledocholithiasis and cholangitis diagnosed 5
Definition
liver enzymes
WBC
ultrasound
MCRP
ECRP
Term
changes in liver ensymes and WBC in choledocholithiasis and cholangitis 9
Definition
increased ALP, GGT, AST, ALT
direct and total bilirubin
amalyase, lipase
WBC left shift
Term
choledocholithiasis and cholangitis ultrasound signs
Definition
see if stone is causing obstruction because duct will be dilated (not helpful if no obstruction)
Term
choledocholithiasis and cholangitis MCRP signs
Definition
identify the biliary anatomy including site and origin of obstruction
Term
choledocholithiasis and cholangitis ECRP signs
Definition
same as MCRP but can remove stone
Term
choledocholithiasis and cholangitis management 3
Definition
if detected before elective removal: remove via ECRP before surgery or laproscopically at surgery (not as safe)

if removal of stones laproscopically at time of GB

if has cholangitis: emergent drainage of biliary tree, broad spectrum antibiotics, hydration, analgesia
Term
complications of cholangitis
Definition
pt typically develops ileus (no movement of intestine) after treatment so NG suction is needed
Term
choledocholithiasis and cholangitis prognosis
Definition
15% pass stone through cystic duct into CBD and into duodenum without issue
rest get stuck causing significant morbidity
Term
gallstone pancreatitis: cause 2
Definition
alcohol
gallstones
Term
gallstone pancreatitis: pathogenesis
Definition
passage of stone through cystic duct into CBD where it gets lodged in ampulla of vater causing ductal HTN and injury of pancreas a liver
Term
gallstone pancreatitis: diagnosis 6
Definition
increased amalyase, lipase, ALP
epigastric pain radiatinig into back
nausea and emesis
Term
gallstone pancreatitis: treatment
Definition
volume rescusitation
antibiotics if severe
surgery done before leaving hospital

**if stone passes spontaneously and pt improves then they are taken for GB removal with or w/o cholangiogram and removal of stones

**if stone does not pass then pt is taken for ECRP with removal of stone and stent placement
Term
gallstone ileus: cause
Definition
erosion of large stone through GB into intestine causes cholecystoentric fistula
stone passes to most narrow point at terminal ileum
Term
gallstone ileus: symptoms
Definition
typical bowel obstruction complaints
Term
gallstone ileus: signs on x-ray
Definition
SBO and AIR IN BILIARY TREE
GS in RLQ if stone has enough calcium
Term
gallstone ileus: treatment 2
Definition
healthy pt: remove stone via enterotomy/cholecystectomy and repair fistula

elderly/comorbid: remove stone with cholecystectomy, fistula repair
Term
cause of bile duct injury 2
Definition
>90% iratogenic as result of sirgery
75% occur in laproscopic cholecystectomy
Term
bile duct injury symptoms 3
Definition
post op pt with jaundice, abd pain
bilious output from surgical drain or sepsis
Term
bile duct injury prognosis
Definition
minor leak from accessory duct will usually heal spontaneously with drainage of fluid and collection alone

cystic duct injury is usually treated with drainage and ECRP with stenting
Term
treatment of major bile duct injury with no significant loss of length discovered in operation
Definition
avulsion, devascularization, then primary repair
Term
treatment of major bile duct injury long length discovered in operation
Definition
slvulsion, devascularization, repair with biliary enteric anastamosis
Term
treatment of major bile duct injury post operation
Definition
reconstruction is delayed until anatomy has defined, bile leak controlled, sepsis resolved
Term
2 tools used in major bile duct reapir and why
Definition
clip: used when you clip the bile duct

choledochojyunstomy; drain common duct into jejunum
Term
10 caues of acute abdomen hemorrhage
Definition
solid organ trauma
leaking or ruptured arterial anrueysm
GI bleeding diverticulum
AV malformation of GI tract
intestinal ulceration
aortoduodenal fistula after aortic vascular grat
hemorrhagic pancreatitis
mallory weiss syndrome
spontaneous rupture of spleen
Term
what normally causes appendiciits
Definition
always acute
fecalith causes obstruction of lumen
Term
treatment of bile duct injury if occurs in laproscopic cholecystectomy
Definition
do primary repair with T tubule and drain
Term
WHAT IS THE MOST COMMON HERNIA IN MEN AND WOMEN
Definition
INDIRECT INGUINAL
Term
WHAT IS A SPIGELIAN HERNIA
Definition
OCCURS THROUGH SEMILUNAR LINE LATERAL TO RECTUS MUSCLE
Term
WHAT IS THE CAUSE OF ACUTE APPENDICITS
Definition
FECALITH CAUSES OBSTRUCTION OF LUMEN
Term
HOW IS GERD EVALUATED
Definition
DEMEESTER SCORE ON BRAVE PROBE STUDY OR PROVEN REFLUX ESOPHAGITIS
Term
WHAT IS THE BEST METHOD OF DIAGNOSIS FOR GALLSTONE ILEUS
Definition
ULTRASOUND
Term
HOW IS A DUODENAL ULCER PERFORATION TREATED
Definition
GRAMS PATCH WITH TRUNCAL VACOTOMY IF INDICATED
Term
what are the 4 areas of the stomach and their function
Definition
cardia: most proximal portion adjacent to esophagus

fundus: accomodation (receptive relaxation, has gastric pacemaker which initiates motor activity)

body: storage and peristaltic grinding of food against closed pylorus

antrum: most distal portion, has pylorus (controls rate of gastric emptying and prevents duodenal reflux
Term
5 parts of duodenum and their function
Definition
duodenal bulb

descending (2nd): intense pacemaker, site of bile and pancreatic secretion entry into GI tract

transverse(3rd)

ascending (4th)

terminates into jejunum at ligament od treitz
Term
what causes peptic ulcer disease
Definition
H, pylori and nsAIDS alter balance between protective and harmful elements of gastric enivornment leading to ulcers
tobacco and alcohol are risk factors
Term
signs of peptic ulcer disease 4
Definition
epigastric pain radiating into back
gnawing pain
associated with food intake
causes anorexia and weight loss
Term
signs of perforated ulcer and why
Definition
severe upper abdominal pain due to free air in peritoneal cavity
Term
repair of perforated ulcer in OR
Definition
grahm patch over ulcer
Term
signs of gastric outlet obstruction 2 and cause
Definition
nausea, emesis, caused by scarring from ulcer
Term
tx of gastric outlet obstruction 4
Definition
NG decompression
parenteral nutrition
NPO
after recussitation take to OR for surgical resection
Term
tx of peptic ulcer disease
Definition
surgery for bleeding, obstruction, perforation or malignancy

if refractive to antibiotics and acid supression do vagotomy and pyloroplasty
Term
what is vagotomy and pyloroplasty
Definition
stomach has vagal input transected leading to non relaxing pylorus then pyloroplasty is done
Term
signs and symptoms of acute pancreatitis 7
Definition
severe upper abdominal pain radiates into back
exacerbated by laying flat, improved with sitting or standing
nause and vomiting
upper abdominal tenderness
gaurding
rebound tenderness
Term
signs of herorrhagic pancreatitis 3
Definition
Grey-turner sign: bleed may track along retroperitoneal tissue causing ecchymosis of flank
cullen sign: umbilicus
fox sign: inguinal canal
Term
lab signs showing acute pancreatitis 12
Definition
leukocytosis
amaylase
lipase

if severe: LFT, BUN, CR, hypocalcemia, hyperglycemia

CT: preferred, sensitive to peripancreatic fluid, pancreatic edema, necrosis

ultrasound: consider to evaluate for gall stones
Term
who is appendicitis more comon in
Definition
males
Term
why do you always need to do all tests for appendicits and not just one
Definition
if lying in pelvis it is on obturator muscle but if in other positions obturator test wont show positive
Term
complications of appendicitis 4
Definition
carcinoid tumor of appendix
adenocarcinoma of cecum
perforation
abscess
Term
what is a strangulated hernia
Definition
herniated tissue has compressed its blood supply and the herniated tissue will most likely become necrotic
Term
what is the most common hernia in men and women
Definition
indirect inguinal
Term
indirect inguinal hernia cause
Definition
bowel,omentum, or intraabdominal organ protrudes through deep inbuinal ring lateral to inferior epigastric vessels

congenital lesion related to patent processus vaginalis which predisposes to the hernia

anticedent event causes it (heavy lifting)
Term
what is a direct inguinal hernia
Definition
protrudes directly through center og hesselbach's triangle medial into inferior epigastric vessels

acquired lesion and more common in older men
Term
what is a spigelian hernia
Definition
through semilunar line lateral to rectus muscle at junction with like of douglas
Term
what percent of body weight is solids
Definition
27%
Term
what percent of average body weight is adipose
Definition
15%
Term
3 causes of hypovolemia
Definition
fluid overload
end stage renal patients
CHF patients
Term
normal values: sodium
Definition
135-145
Term
normal values: potassium
Definition
3.5-5
Term
normal values: calcium
Definition
8-10.5
Term
normal values: Mg
Definition
1.5-2.5
Term
normal values: phosphate
Definition
2.5-4.5
Term
normal values: chloride
Definition
95-105
Term
where are most cations found
Definition
98% in the intracellular fluid
Term
3 effects of hyperkalemia
Definition
muscle
peaked T waves on EKG
CBIGK
Term
3 signs of hypokalemia
Definition
weakness
leg cramps
U waves on EKG
Term
how much fluid is lost from the skin, lungs, urine/kidney, GI/intestines
Definition
skin 600mL/d
lungs 400mL/d
urine/kidneys 1500mL/d
GI/intestines 100mL/d
Term
how is total blood volume determined
Definition
RBC volume 2% + plasma volume 5% = 7%
Term
how many does does the blood circulate through the body perminute
Definition
3x
Term
how is the intrinsic coagulation pathway monitored, what is normal
Definition
PTT: 25-35 seconds
ACT
Term
how does heparin work
Definition
strong acid indirectly binds antithrombin 3 (AT3)
accelerated AT3 interacton to neutralize factors II, IX, X, XI, XII, XIII
Term
antidote to heparin
Definition
rotamine
Term
MOA parasurgel
Definition
P2Y12 platelet inhibitor
Term
MOA dabigatran
Definition
direct thrombin inhibitor
Term
MOA rivaroxaban
Definition
factor Xa inhibitor
Term
whats in packed RBC 4
Definition
citrate, phosphate, dextrose-adenine,
HCT 75%
Term
how does packed RBC affect the body
Definition
one unit PRBC increases Hb by 1g/dL or HCT by 30%
Term
normal lifespan of platelet, normal platelet count, level of platelets that causes spontaneous bleeding
Definition
life 7-10d
level 140,000 - 400,000
bleeding <20,000
Term
how does fresh frozen plasma affect the body
Definition
due to liable clotting factors V and VIII
expires 24h after thawing
Term
why would you need a massive transfusion (replace whole blood in a few hours)
Definition
P: platelets, potassium
A: ARDS, acid/base changes
T: temperature (hypothermia)
C: citrate intoxication, hypocalcemia
H: hepatitis, syphilis, HIV
Term
what is the most common hereditary bleeding disorder, what is wrong, how is it diagnosed
Definition
von willibrand disease, unable to use vFW to make platelet plug
affects function of factor VIII
prolonged PTT
Term
what is a differential diagnosis
Definition
process of elimination in which you narrow down possible cause of your patient symptoms
Term
what is the differential diagnosis for abdominal pain 9
Definition
major anatomy
minor anatomy: msk, vascular, neurological, lymphatic, extra-abdominal
infectious
inflammatory
tumor: benign or malignant
Term
anatomy of RUQ 7
Definition
liver, gallbladder, stomach, kidney, pancreas, lung, vascular
Term
ddx RUQ 9
Definition
cholelithiasis, hepatitis, GERD, gastritis, PUD, pancreatitis, kidney stones, CHF, pneumonia
Term
anatomy of epigastric region 4
Definition
stomach
bowels
pancreas
lungs
Term
DDX epigastric pain
Definition
GERD
gastritis, PUD
IBS
chrons disease
appendicitis
pancreatitis
diabetic ketoacidosis
pneumonia
diabetic ketoacidosis
pneumonia
Term
anatomy of LLQ 5
Definition
intestines, genitourinary tract, gynecologic, msk, vascular
Term
DDX of nausea and emesis
Definition
cholelithiasis
cholecystitis
GERD
gastritis
PUD
bowel obstruction
food poisoning
IBS
IBD
hypo/hyperthyroidism
hypercalcemia
addisons disease
urosepsis
uremia
anorexia
bulemia
meningitis
vertigo
Term
most common viral infection causing diarrhea in adults
Definition
norovirus
Term
most common viral infection cause diarrhea in kids
Definition
rotavirus
Term
4 causes of GI bleed
Definition
diverticulum
aortoenteric fistula
intussception
chrons disease
Term
6 causes of colorectal bleed
Definition
diverticulosis
AV malformation
hemorrhoids
fissures
chrons disease
ulcerative colitis
Term
BPH histological definition
Definition
histological definition that is non malignant enlargement of prostate due to increased cellular growth
Term
BPH clinical definition
Definition
prostate >20g
Term
epidemology BPH
Definition
40s 8% men
50-60s 50% men
80s 90% men
Term
cause of BPH
Definition
presence of prostate growth factors and DTH contribute to development of BPH over time

studies show that imbalance in regulation of growth factorsand apoptosis is ultimate etiology

studies show genetic component for BPH and risk of developing symptoms in persons lifetime
Term
PROBLEMS ASSOCIATED WITH BPH 5
Definition
BLADDER CALCULI
UTI
RENAL FAILURE
HEMATURIA
LOSS OF BLADDER FUNCTION
Term
how do you get a direct inguinal hernia, what is the tx
Definition
congenital located going down through inguinal internal ring
emergency surgery could become strandulated
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