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Sulfonamides
Static group of Antibiotics that inhibit 1st step in production of folate
8
Pharmacology
Graduate
02/07/2011

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Cards

Term
Sulfisoxazole
Definition
In combination with Erythromycin for recurrent otitis media; Oral
Term
Sulfamethoxazole
Definition
In combination with trimethoprim; Single most effective sulfonamide still on market; used to treat various urinary, respiratory, and GI infection; Oral
Term
Sulfacetamide
Definition
Bleph-10; topical
Term
Silver Sulfadiazine
Definition
Topical antibiotic used to treat burns to prevent sepsis.
Term
Mafenide
Definition
Topical antibiotic for burns; Can cause metabolic acidosis due to inhibition of carbonic anhydrase
Term
Trimethoprim
Definition
DHFR Inhibitor; inhibits bacterial DHFR; side effects: blood dyscrasias
Term
Methotrexate
Definition
DHFR Inhibitor; inhibits mammalian, bacterial, and protozal DHFR; used for psoriasis and various cancers.
Term
Pyrimethamine
Definition
DHFR Inhibitor; inhibits protozal DHFR -> antimalarial drug
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