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Succinylcholine (Anectine)
n/a
8
Pharmacology
Undergraduate 1
01/29/2012

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Cards

Term
CLASS
Definition
Neuromuscular blocking agent (depolarizing)
Term
ACTIONS
Definition
-Skeletal muscle paralysis (including respiratory muscles)
-Prevents neuromuscular transmission by blocking the effect of acetylcholine at the myoneural junction
-Has no analgesic or anxiolytic effects
Term
INDICATIONS
Definition
-Rapid Sequence Intubation (RSI)
-Skeletal muscle paralysis to facilitate endotracheal intubation (after administration of Versed for amnesia)
Term
DOSAGE/ROUTE
Definition
1.5mg/kg IVP (over 10-30 seconds)
Term
SIDE EFFECTS
Definition
-Prolonged paralysis
-Hypotension
-Bradycardia (especially in children)
Term
CONTRAINDICATIONS
Definition
-Patients with known hypersensitivity to the drug
-Children and neonates
Term
SPECIAL INFO
Definition
-Should not be administered unless persons skilled in endotracheal intubation are present
-ET equipment must be available and working
-O2 equipment, ventilatory management equipment, and emergency resuscitative equipment/drugs must be available
-Paralysis occurs within 1 minute and lasts for approximately 8 minutes
-Has no effect on consciousness or pain threshold, adequate amnesia/analgesia should ALWAYS be used concurrently
Term
PEDIATRIC NOTE
Definition
Not recommended
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