meta-

Prefix

change

metamorphosis: a change in form

metabolism: chemical changes in an organism

multi-

Prefix

many, much 

multitude: an indefinite number; many

multicolored: many - colored 

para-

Prefix

next to, almost,

beyond, abnormal

paraphrase: to restate almost like the original

parallel: next to each other without ever meeting

-ann-

-enn-

Roots 

year

biannual: happening twice each year

perennial: lasting through many years

-mut-

Roots

change

permutation: the act of changing

mutant: a new type of organism due to a change