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STRUCTURES OF NUCLEOTIDES
DNA
39
Biology
12th Grade
12/02/2024

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Term
What are nucleic acids?
Definition
Polymers made from monomers called nucleotides.
Term
What are the three main parts of nucleotides and what are they combined by?
Definition
-Phosphate group
-Pentose sugar
-Organic nitrogenous base
Term
What are the two groups of nitrogenous base?
Definition
Pyrimidine- single ring
Purine- double ring
Term
Which bases are pyrimidine?
Definition
Thymine, cytosine, uracil
Term
Which bases are purine?
Definition
Guanine, Adenine
Term
What does DNA stands for?
Definition
Deoxyribonucleic acid
Term
What is DNA?
Definition
A very stable and large molecule found as chromatin in nucleus and small amounts in mitochondria and chloroplasts.
Term
What are the functions of DNA? (2)
Definition
1. Carries the genetic code for protein synthesis
2.Replicates in dividing cells
Term
What does DNA consist of?
Definition
Two polynucleotide strands twisted into a double helix
-Deoxyribose sugar
-A-T and G-C
Term
What does antiparallel mean?
Definition
Two strands run in opposite directions
Term
What type of bond are the nucleotides held by?
Definition
Phosphodiester
Term
On which end would each strand end if the phosphate group attached to the 5th C atom on one pentose sugar and 3rd C atom on another?
Definition
One strand finishes on C-5- 5 prime end
One strand finishes on C-3- 3 prime end
Term
What is the 'backbone' and it's function?
Definition
The two sugar-phosphate-protect the genetic information stored within the sequence of bases.
The bases are complementary held by H bonds.
Term
How many hydrogen bonds are between guanine and cytosine?
Definition
3
Term
How many hydrogen bonds between adenine and thymine?
Definition
2
Term
What does RNA stands for?
Definition
Ribonucleic acid
Term
What is RNA?
Definition
Short-lived molecule, found mainly in the cytoplasm and in nucleus
Term
Is RNA single or double stranded?
Definition
Single stranded polynucleotide
Term
What does RNA consists of?
Definition
-Ribose pentose sugar
- A-U (Uracil) and G-C
Term
What is the function of RNA?
Definition
Involved in protein synthesis
Term
What are the 3 types of RNA involved in protein synthesis?
Definition
mRNA (messenger)
tRNA (transfer)
rRNA (ribosomal)
Term
What is mRNA?
Definition
Single stranded molecule that carries the genetic code for a specific protein form DNA in the nucleus to ribosomes in the cytoplasm
Term
What is tRNA?
Definition
Transfers specific amino acids to the ribosome.
Single RNA forms a coverleaf shape held by H bonds between certain base pairs
Term
What is rRNA?
Definition
Forms a large complex molecule with protein : a ribosome.
Ribosomes translate the genetic code and join amino acids together to form polypeptides.
Term
Where are H bonds found in RNA?
Definition
Only in tRNA
Term
What is a gene?
Definition
A sequence of DNA
Term
What is the function of gene?
Definition
Codes for the sequence of amino acids in one polypeptide.
Term
What are the two stages of protein synthesis?
Definition
Transcription
Translation
Term
What is transcription?
Definition
Occurs in the nucleus
DNA is read by enzymes and used to make a single stranded mRNA molecule
Leaves the nucleus through a nuclear pore and travels to a ribosome
Term
What is translation?
Definition
Occurs at ribosome
mRNA attaches to the ribosome, and a tRNA brings a specific amino acid
Ribosomal enzymes catalyse the formation of peptide bonds to form the primary structure of a new polypeptide.
Term
What is ATP?
Definition
A nucleotide found in all living organisms.
Term
What are the structures it includes?
Definition
-3 Phosphate groups
-A Ribose Sugar
-Nitrogenous base Adenine
Term
What does respiration do to ATP?
Definition
Oxidises glucose in a series of small reactions release energy in the form of ATP
Term
Why is ATP called 'universal energy currency'?
Definition
It provides energy for many metabolic reactions in all living organisms.
Term
Uses of ATP?
Definition
-Active Transport
-Muscle Contraction
-Nerve Impulse Transmission
Term
How is ATP formed?
Definition
ATP synthase combines ADP and Pi in a condensation reactions which inputs 30.6 kJ/mol of energy in an endergonic reaction.
Term
What is the addition of Pi called?
Definition
Phosphorylation
Term
How is ATP hydrolysed?
Definition
ATPase hydrolyses phosphate bonds releasing a small packet of energy (30.6 kJ/mol) which forms ADP and Pi in an exergonic reaction.
Term
4 Key Differences between Glucose and ATP
Definition
1. Glucose needs many enzymes to release energy, ATP needs only one
2.Glucose releases large quantities of energy that may not be needed realising lots of heat, ATP releases small packets of energy (30.6) when and where it is needed
3.Glucose only releases energy through respiration, ATP is universal
4. Glucose requires proteins to cross a membrane, ATP is easily transported across.
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