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Structure and Function of the Pulmonary System
Ch 32
104
Science
Graduate
03/27/2012

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Cards

Term
How does gas exchange work? 
Definition
Enviornment to Blood 
Term
What is ventilation? 
Definition
Mechanical movement of gas or air into and out of the lungs
Term
What is respiration? 
Definition
The exchange of oxygen and carbon dioxide during cellular metabolism 
Term
What is Diffusion? 
Definition
The Movement of gasses 
Term
What is perfusion? 
Definition
The movement of blood 
Term
What are the pulmonary structures? 
Definition
  • Airways
  • Blood vessels
  • Chest wall
  • Lungs
Term
What are the parts of the upper airway? 
Definition
  • Larynx
  • Nasopharynx
  • Oropharynx
Term
What does the larynx do?
Definition
Conncets upper and lower airways 
Term
What are the parts of the lower airways?
Definition
  • Trachea
  • Bronchi
  • Terminal Bronchioles 
Term
What parts make up the conducting airways?
Definition
  • Trachea 
  • Segmental Bronchi 
Term
What is the function of conducting airways?
Definition
To bring air in
Term
What are the respiratory units?
Definition
  • Some bronchioles
  • Alveolar ducts
  • ** Chart on slide 5 
Term
What is the Carina?
Definition
Where the trachea bifurcates or splits 
Term
What are Alveoli?
Definition
Primary gas exchange units 
Term
Alveoli are made up of what type of cells? 
Definition
Epithelial Cells 
Term
These epithelial cells provide 2 functions what are they? 
Definition
  • Provide alveolar structure
  • secret surfactant 
Term
What is surgactant? 
Definition
It decreases the surface tension and facilitates gas exchange 
Term
Alveoli are the ...
Definition
Primary gas exchange units 
Term
What are Pores of Kohn? and thier function?
Definition
  • Tiny pores 
  • Allow for air to pass through the septa from alveolus to alveolus 
  • Provide collateral ventilation and even air districution 
Term
How many alveoli do you have at birth? 
Definition
25 million 
Term
How many alveoli do you have as an adult?
Definition
300 Million 
Term
When comparing pulmonary circulation and systemic circulation pressure is ... 
Definition
  • lower in pulmonary circulation 
  • 18 mmHG
Term
How many vessels are full with blood at any given time in the body?
Definition
1/3
Term
The pulmonary artery divides and enter the lung where? 
Definition
At the hilum 
Term
Each bronchus and bronchiole has an ...
Definition
Accompanying artery or arteriole 
Term
Characteristics of the alveolar-capillary membrane 
Definition
  • It is the interface of alveolar and capillary walls
  • It is a thin membrane 
Term
The chest wall is in what cavity? 
Definition
Thoracic cavity 
Term
What are the parts of the chest wall?
Definition
  • Skin
  • Ribs
  • Intercostal muscles 
Term
What is the Pleura? 
Definition
Serous membrane that surrounds the lungs 
Term
The pleura is made up of what 2 layers
Definition
  • Parietal - outside 
  • Visceral - covers the organ 
Term
There is a space in between these 2 layers what is it called? 
Definition
Pleural space/cavity 
Term
What is in the pleural space? 
Definition
Pleural fluid 
Term
The pleura has what kind of pressure? 
Definition

Negative pressure

-4 to -10 mmHg

Term
Where is the respiratory center located in the body?
Definition
The brain stem 
Term
What are the 4 areas that are responsible for breathing in the brain stem?
Definition
  • Dorsal group
  • Ventral respiratory group
  • Pneumotaxic center
  • Apneustic Center
Term
Functions of the Dorsal Group 
Definition
  • Inspiration
  • Sets automatic rhythm
  • Receives input from peripheral chemoreceptors 
Term
Functions of the Ventral Respiratory Group 
Definition
  • Inspiration and expiration
  • Usually inactive
  • Active with increased ventilatory effort 
Term
Function of the Pneumotaxic Center?
Definition
Inspiration 
Term
Function of the Apneustic Center 
Definition
Inspiration and Expiration 
Term
What system controls ventilation? 
Definition
Autonomic Nervous System 
Term
What does the Autonomic Nervous System do to control ventilation? 
Definition
  • makes smooth muscles contract of relax
  • Alters airway lumen diameter 
Term
What 3 things do Chemoreceptors monitor? 
Definition
  • pH
  • CO2
  • O2
Term
2 types of chemoreceptors
Definition
  • Central 
  • Peripheral 
Term
Central receptors function 
Definition
  • Reflects CO2
  • Sense changes in pH of cerebrospinal fluid 
Term
Peripheral receptors function 
Definition
  • Sense changes in O2
Term
Where are peripheral receptors located? 
Definition
In the aorta and corotid bodies 
Term
What is hypoxemia?
Definition

Low O2 in arteral blood

Causes low O2 sat 

Term
3 types of Lung receptors 
Definition
  • Irritant Receptors
  • Stretch Receptors
  • J Receptors 
Term
Irritant receprots are located where? 
Definition
In epithelium of conducting airways 
Term
What are irritant receptors sensitive to? 
Definition
  • Noxious aerosols
  • Gasses 
Term
Irritant receptors cause 
Definition
  • Cough
  • Bronchoconstriction 
Term
Where are stretch receptors located? 
Definition
In smooth muscles of airways 
Term
What are strech receptors sensitive to? 
Definition
Increases in lung size or volume 
Term
Stretch receptors cause
Definition
Decrease respiratory rate and volume
Term
Juxtapulmonary capillary or J receptors are located where? 
Definition
Near capillaries in alveolar septa 
Term
J Receptors are sensitive to what? 
Definition
Increased pulmonary capillary pressure 
Term
J Receptors cause? 
Definition
Shallow breathing 
Term
What are lung volumes/capacities? 
Definition
  • Dead Space
  • TV
  • IRV
  • ERV
  • VC
  • Residual Volume 
Term
Dead Space 
Definition

Oropharynx to division 16

Equal to ideal body weight

 

Term
TV
Definition
Normal air exchange 
Term
IRV
Definition
Additional air that could be inhaled 
Term
ERV
Definition
Remaining air that can be forcefully expired after normal expiration 
Term
VC 
Definition

Vital capacity 

Max air that can enter/leave 

Term
Residual Volume 
Definition
Air remaining in alveoli 
Term
Surfactant function 
Definition
Lowers surface tension on alveolar surface 
Term
What are the 2 elastic properties of the lung and chest wall?
Definition
  • Elastic recoil
  • Compliance 
Term
Elastic Recoil 
Definition
Tendency to return to resting state after inspiration 
Term
Compliance 
Definition

Measures distensibility of lung and chest wall

This is oposite of elasticity 

Term
What is airway resistance determined by? 
Definition
  • Length 
  • Radius
  • Cross section of airways
  • Density
  • Viscosity
  • Gas Velocity 
Term
How is work of breathing determined? 
Definition
By muscular effort needed for ventilation 
Term
What is compliance? 
Definition
  • It is the measurement of lung and chest wall ability to distend
  • Degree of "stiffness"
Term
Compliance = ???
Definition

Volume (volume of air moved)/Pressure (force to move the air )

 

Term
Low compliance is 
Definition
Increased work of inspiration 
Term
Low compliance orrcus when you have what kind of lungs? 
Definition
Stiff 
Term
What is high compliance? 
Definition
Increased work of expiration
Term
What kind of lungs cause high compliance? 
Definition
Baggy lungs 
Term
What major mucles are used on inspiration? 
Definition
  • Diaphragm 
  • External intercostals 
Term
What accessory muscles are used on inspiration?
Definition
  • Sternocleidomastoid 
  • Scalene 
Term
What are the major muscles used on expiration? 
Definition
NO major muscles 
Term
What are the accessory muscles used on expiration?
Definition
  • Abdomen
  • Internal intercostals 
Term
Why are there no major muscle of expiration? 
Definition
Bc expiration is passive 
Term
What way does your diaphragm move when you inspire?
Definition
It moves down 
Term
Law of Laplace 
Definition
Smaller the radius of a sphere (alveoli) the greated the surface tension 
Term
What is surfactant? 
Definition
Lipoprotein that lines the alveolus 
Term
What is the function of surfactant?
Definition
Term
Smaller radus =?
Definition
Decreases surface tension 
Term
Larger radius =?
Definition
Increases surface tension 
Term
What is Barometric pressure at sea level?
Definition
760 
Term
What is barometric pressure at salt lake city? 
Definition
600
Term
What is O2 needed on Mt Everest? 
Definition
Bc barometric pressure on Mt Eversity is much lower 
Term
What are the steps of O2 transport?
Definition
  • Ventilation of the lungs
  • O2 diffusion from alveoli into capilary blood
  • Perfsion of systemic capillaries with oxygenated blood
  • O2 diffusion from systemic capillaries into cells 
Term
Steps of Carbon Dioxide gas transport? 
Definition
  • CO2 diffusion from cells into systemic capillaries
  • Occurs in reverse order as O2
Term
Where does atalectisis occur? 
Definition
The base of the lungs 
Term
What do you do when using an incentive sparamator? 
Definition
You INHALE
Term
Oxygen saturation =?
Definition
Percent available hemoglobin bound to oxygen 
Term
What does a shift to the right mean in the oxyhemoglobin curve? 
Definition
  • Acidosis
  • Increased CO2
Term

What does a shift to the left mean in the oxyhemoglobin curve? 

Definition
  • Alkalosis
  • Decreased CO2
Term
What are the characteristics of CO2 that is transported in blood? 
Definition
  • Dissolved in plasma
  • It is a bicarbonate
  • It is a carbamino compound 
Term
CO2 is how many more times soluble that O2?
Definition
20X
Term
Late clinical manifestations of hypoxemia 
Definition
  • Stupor
  • Decreased BP
  • Myocardium receiving inadequate O2 
Term
What is hypoxic pulmonary vasoconstriction caused by? 
Definition
Low alveolar O2
Term
What happens during hypoxic pulmonary vasoconstriction?
Definition
  • Blood is shunted to other well ventilated portions of the lungs 
  • Better ventilation and perfusion matching 
Term
Chronic alveolar hypoxia can lead to ... 
Definition
Pulmonary artery hypertension 
Term
What else causes pulmonary artery constriction?
Definition
Acidemia 
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