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Structure and components
Structure and components
5
Medical
Undergraduate 2
07/18/2007

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Term
Specialized Organelles
Definition
1. Sarcolemma: plasma membrane
2. T-tubules: extension of plasma membrane to allow depolarization to take place within the cell
3. Sarcoplasmic Reticulum: specialized ER
Term
Skeletal Muscle
Definition
a. Surrounded by connective tissue; acts as a shrink wrap
b. Contains nerve and blood vessels.
c. Consists of bundles of muscle fibers
Term
Muscle Fibers
Definition
a. Same as muscle cells
b. Consists of myofibrils
Term
Myofibrils
Definition
a. Contains sarcomeres: the functional unit of skeletal muscle cells, consists of thick and thin filaments
Term
Myofibrils
Definition
1. Contains sarcomeres
2. Structure of sarcomeres
a.Z-lines: create boundaries between sarcomeres; end points
b. Thin filaments: protrudes from z-lines, composed of actin and two regulatory proteins: troponin (binding site for Ca2+) and tropomyosin (covers actin in a resting state)
c. Thick filaments: composed of myosin
i. Myosin have two “heads”: one binds to actin (actin binding site) and one binds to ATP (ATP binding site)
d. Elastic Fibers: help align actin and myosin
i. Nebulin: helps keep actin aligned within the sarcomere
ii. Titin: provides elasticity and stabilizes myosin
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