Term
Step 1: Binding of myosin to actin
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Definition
| ADP and Pi are bound to ATPase site of myosin head. Creates high affinity for actin and the myosin head binds to thin filament |
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Term
Step 2: Power Stroke
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Definition
| Myosin head pivots and pulls thin filament toward the M-line |
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Term
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Definition
| ADP released from myosin head and myosin goes into low-energy form tightly bounding itself to actin. |
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Term
Step 4: Unbinding of Myosin and Actin
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Definition
| ATP enters the ATPase site on myosin head triggering a conformational change, decreasing myosin's affinity for actin and detaching myosin from actin. |
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Term
Step 5: Cocking of the Myosin Head
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Definition
| ATP is split by hydrolysis releasing energy which is captured by the myosin molecule and it returns to its high-energy conformation. ADP and Pi remain bound to ATPase site. |
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