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Step 1 - Psychiatry
Psych
74
Medical
Graduate
03/17/2014

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Cards

Term
Classical Conditioning
Definition
Learning in which a natural response is elicited by a learned stimulus
Term
Dissociation
Definition
drastic changes to personality to avoid emotional stress
Term
Displacement
Definition
Process whereby avoided areas and feelings are transferred to some neutral person or object
Husband > wife, Wife >child
Term
Fixation
Definition
Partially remaining at a more childish level of development
Term
Projection
Definition
An unacceptable internal impulse is attributed to an external source
Term
Reaction formation
Definition
Process whereby a warded off feeling or idea is replaced by an emphasis on its opposite
Term
Splitting
Definition
Belief that people are either all good or all bad
Term
Altruism
Definition
guilty feelings alleviated by unsolicited generosity towards others
Term
Infant deprivation effects
Definition
Weak, wordless, wanting, wary
Term
Child neglect
Definition
Failure to provide a child with adequate food, shelter, supervision, eduction or affection
Term
ADHD
Definition
Onset before Age 7
Decreased frontal lobe volumes
Tx: methylphenidate, atomoxetine, dextroamphetamine
Term
Tourette syndrome
Definition
Onset before age 18
Sudden, rapid, recurrent, nonrythmic, sterotyped motor and vocal tics that persist > 1yr
Tx: antipsychotics
Term
Seperation anxiety disorder
Definition
Common onset at 7-9 years of age
Factitious physical complaints
SSRIs, relaxation techniques
Term
Rett's disorder
Definition
X linked, exclusively in girls
Regression, loss of development around ages 1-4
Mental retardation, ataxia, stereotyped hand wringing
Term
Child disintegrative disorder
Definition
Age of onset 3-4 yrs
Marked regression in multiple areas of functioning, after 2 years of normal development
More common in boys
Term
NT changes in diff diseases
Definition
Anxiety: Inc NE; Dec GABA, serotonin
Depression: Dec NE, serotonin, and dopamine
Alzhemiers: Dec Ach
Huntingtons: Dec GABA, Ach; Inc Ach
Schizophrenia: Inc DA
Parkinsons: Dec DA; Inc serotonin and ach
Term
Korsakoff's amnesia
Definition
Anterograde amnesion caused by thiamine deficiency, assoc destruction of the mammillary bodies.
Assoc with confabulations
Term
Dissociative amnesia
Definition
Inability to recall important personal information
Term
Delerium
Definition
Waxing and waning consciousness with acute onset
Disorganized thinking, hallucinations (often visual), disturbances in sleep wake cycle
*check for drugs with anticholinergic effects
Term
Hallucination types
Definition
Visual- most commonly from medical illness
Auditory- psych illness
olfactory- psychomotor epilepsy and brain tumors
Gustatoy- rare
Tactile- alcohol withdrawal, cocaine abusers
Hypnogogic - Occurs when going to sleep
Hypnopompic - occurs while waking from sleep
Term
Schizophrenia
Definition
Decline in mental status happening over 6 months
Term
Brief psychotic disorder
Definition
<1 month
Term
Schizopheniform disorder
Definition
1-6 months
Term
Schizoaffective disorder
Definition
At leat 2 weeks of stable mood with psychotic symptoms, plus a major depressive, manic or mixed episode
Term
Delusional disorder
Definition
Fixed, persistent non bizarre belief system lasting > 1 month
Term
Dissociative identity disorder
Definition
Multiple personality disorder
History of sexual abuse
Term
Manic Episode
Definition
Persistently elevated, expansive or irritable mood lasting over 1 week
Term
Bipolar disorder
Definition
At least one manic or hypomanic episode
*Do not use antidepressants
Tx: mood stabilizers, atypical antipsychotics
Term
Cyclothymic disorder
Definition
Milder form of bipolar, lasting at least 2 years
Term
Major depressive disorder
Definition
Self limited disorder with major depressive symptoms, lasting 6-12 months
At least 5 of the symptoms for 2 or more weeks
SIG E CAPS
Term
Atypical depression
Definition
Mood reactivity, reversed vegetative symptomts (hypersomnia, weight gain), leaden paralysis
Most common subtype
Tx: MAOIs, SSRIs
Term
Maternal (postpartum) blues
Definition
Starts 2-3 days after delivery
Usually resolves within 10-14 days
Tx: supportive
Term
Postpartum depression
Definition
Starts within 4 weeks of delivery, lasts 2 weeks to a year or more
Tx: antidepressants, psychotherapy
Term
Postpartum psychosis
Definition
Delusions, hallucinations, possible homicidal, suicidal attemps
Lasts days to 4-6 weeks
Tx: antipsychotics, antidepressants
Term
Risk factors for suicide completion
Definition
Ethanol, sickness, no spouse, etc
Term
Panic disorder
Definition
Peaks in 10 min
Tx: SSRIs, venlafaxine, benzodiazepines
Term
OCD
Definition
Associated with tourette's syndrome
Tx: SSRIs, clomipramine
Term
PTSD
Definition
Persisten reexperiencing of a traumatic event
Disturbance lasts >1 month
Tx: psychotherapy, SSRIs
Term
Acute stress disorder
Definition
Lasts between 2 days and 1 month
Term
Generalized anxiety disorder
Definition
Uncontrollable anxiety for at least 6 months
Assoc sleep disturbances, fatigue
Tx: SSRI's, SNRIs
Term
Adjustment disorder
Definition
emotional symptoms causing impairment
Lasting < 6 months
Term
Somatiform disorder
Definition
Physical symptoms with no identifiable physical cause. Unconcious drives
Term
Somatization disorder
Definition
Multiple organ systems (at least 4 pain, 2 GI, 1 sexual, 1 pseudoneurologic) over a period of years, developing before age 30
Term
Body dysmorphic disorder
Definition
Preoccupation with minor or imagined defect in appearance
Often seeks cosmetic surgery
Term
Cluster A disorders
Definition
Weird:
Paranoid- projection major defense
Schizoid- loner, voluntary withdrawal
Schizotypal- Odd beliefs or magical thinking
Term
Cluster B disorders
Definition
Wild:
Antisocial- conduct disorder for over 18yrs old
Borderline- Unstable mood, self mutilation
Histrionic- sexually provocative
Narcissistic- Grandiosity
Term
Cluster C disorder
Definition
Worried:
Avoidant- Hypersensitive to rejection, desires relationships
OCD
Dependent- submissive and clingy, low self confidence
Term
Alcohol
Definition
Tox: GGT, AST>ALT
WD: DT, use Benzos
Term
Opiods
Definition
Tox: Dec gag reflex, pinpoint pupils. Tx: naloxone
WD: Sweating, dil pupils, flu like symptoms Tx: methadone
Term
Barbiturates
Definition
Tox: marked resp depression
WD: Life threatening cardiovascular collapse
Term
Benzodiazepines
Definition
Tox: Ataxia, Tx: flumazenil
WD: Rebound anxiety, seizure
Term
Stimulants (general)
Definition
Tox: Cardiac arrythmias, anxiety
WD: Depression, lethargy, weight gain, HA
Term
Amphetamines
Definition
Tox: Pupillary dilation
WD: increased appetite, hyper somnolence
Term
Cocaine
Definition
Tox: Pupil dilation, sudden cardiac death Tx: benzos
WD: Malaise, craving
Term
PCP
Definition
Tox: Agitation, analgesia Tx: benzos, rapid acting AP
WD: Depression, disturbance of thought and sleep
Term
LSD
Definition
Tox: perceptual distortion
Term
Heroin addiction
Definition
At risk for Hepatitis, abscess, OD, hemorrhoids, AIDS, Right sided endocarditis
Tx: naloxone and buprenorphine- partial agonist, long acting with fewer WD symptoms than methadone
Term
Wernicke Korsakoff Syndrome
Definition
Thiamine def.
Confusion, opthalmoplegia, and ataxia
May progress to irreversible memory loss, confabulation, personality change
Replace Vit B1- Thiamine
Term
Treatment for certain conditions
Definition
Anxiety- SSRIs, SNRIs, buspirone
ADHD- Methylphenidate, amphetamines
Bipolar disorder- Lithium, VPA, Carbemazapine
OCD- Clomiprimine
Panic disorder- venlafaxine, benzodiazepines
Schizophrenia - Antipsychotics
Tourette's syndrome - Antipsychotics
Term
CNS stimulants
Definition
Methylpehnidate, dextroamphetamine, methamphetamine
Inc catecholamines in the synaptic cleft
ADHD, narcolepsy, appetite control
Term
High Potency AP
Definition
Trifluoperazine, Fluphenazine, Haloperidol
"Tri to fly high"
EPS side effects
Term
Low potency AP
Definition
Chlorpromazine, thiroidazine
Anticholinergic, antihistamine, and a1 blockade
Chlor- corneal deposits
Thior - retinal deposits
Term
All antipsychotics
Definition
Block dopamine D2 receptors
Highly lipid soluble and stored in body fats
Hyperprolactinemia from DA antagonism
NMS- rigidity, myoglobinuria, autonomic instability, hyperpyrexia Tx: Dantrolene, bromocriptine
Term
Atypical Antipsychotics
Definition
Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone
Varied effects on serotonin, DA and a and H1 receptors
Both positive and negative symptoms
Olan/Cloz- significant weight gain
Cloz - agranulocytosis and seizure
Ziprasidone - prolong the QT
Term
Lithium
Definition
Mood stabilizer for Bipolar - blocks relapse and acute manic events, also SIADH
Cause polyuria (AHD nephrogenic DI), teratogenesis (Ebsteins),
Term
Buspirone
Definition
Stim serotonin Rs
Generalized anxiety disorder
*Takes 1-2 weeks to have an effect
Term
SSRIs
Definition
Fluoxetine, Paroxetine, Sertraline, Citalopram
Can cause GI distress, Sexual dysfunction
Serotonin syndrome - (inc risk with MAOI, SNRI, TCA) Hyperthermia, confusion, myoclonus, cardiovascular collapse, flushing, diarrhea, seizures Tx: cyproheptadine
Term
SNRIs
Definition
Venlafaxine, duloxetine, Nefazodone
Depression, GAD, panic disorders
Increased BP, sedation, nausea
Term
TCAs
Definition
Amitryptiline, doxepin, amoxepine
Block reuptake of NE and serotonin
Major depression, bedwetting (imipramine), OCD (clomiprimine)
Sedation, atropine like side effect
Convulsions, coma, cardiotoxicity (Tx with NaHCO3)
Term
MAOIs
Definition
Trancypromine, Phenelzine, Isocarboxyzid, Selegiline
Increase levels of amine NTs (NE, 5HT, DA)
Use - atypical depression, anxiety, hypochondiasis
Tox - hypertensive crisis with ingestion of tyramine containing foods
Term
Buproprion
Definition
Smoking cessation
Inc NE and DA
Tox: stimulant effects, no sexual side effects
Term
Mirtazapine
Definition
a2 antagonist - Inc release of NE and serotonin
Tox- sedation, inc appetite
*good for elderly and anorexics
Term
Maprotiline
Definition
Blocks NE reuptake
Orthostatic htn side effect
Term
Trazodone
Definition
Blocks serotonin reuptake
Primarily for insomnia
Pripaism, nausea, postural Hypotension
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