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Learning in which a natural response is elicited by a learned stimulus |
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drastic changes to personality to avoid emotional stress |
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Process whereby avoided areas and feelings are transferred to some neutral person or object Husband > wife, Wife >child |
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Partially remaining at a more childish level of development |
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An unacceptable internal impulse is attributed to an external source |
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Process whereby a warded off feeling or idea is replaced by an emphasis on its opposite |
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Belief that people are either all good or all bad |
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guilty feelings alleviated by unsolicited generosity towards others |
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Infant deprivation effects |
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Weak, wordless, wanting, wary |
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Failure to provide a child with adequate food, shelter, supervision, eduction or affection |
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Onset before Age 7 Decreased frontal lobe volumes Tx: methylphenidate, atomoxetine, dextroamphetamine |
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Onset before age 18 Sudden, rapid, recurrent, nonrythmic, sterotyped motor and vocal tics that persist > 1yr Tx: antipsychotics |
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Seperation anxiety disorder |
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Common onset at 7-9 years of age Factitious physical complaints SSRIs, relaxation techniques |
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X linked, exclusively in girls Regression, loss of development around ages 1-4 Mental retardation, ataxia, stereotyped hand wringing |
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Child disintegrative disorder |
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Age of onset 3-4 yrs Marked regression in multiple areas of functioning, after 2 years of normal development More common in boys |
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NT changes in diff diseases |
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Anxiety: Inc NE; Dec GABA, serotonin Depression: Dec NE, serotonin, and dopamine Alzhemiers: Dec Ach Huntingtons: Dec GABA, Ach; Inc Ach Schizophrenia: Inc DA Parkinsons: Dec DA; Inc serotonin and ach |
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Anterograde amnesion caused by thiamine deficiency, assoc destruction of the mammillary bodies. Assoc with confabulations |
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Inability to recall important personal information |
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Waxing and waning consciousness with acute onset Disorganized thinking, hallucinations (often visual), disturbances in sleep wake cycle *check for drugs with anticholinergic effects |
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Visual- most commonly from medical illness Auditory- psych illness olfactory- psychomotor epilepsy and brain tumors Gustatoy- rare Tactile- alcohol withdrawal, cocaine abusers Hypnogogic - Occurs when going to sleep Hypnopompic - occurs while waking from sleep |
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Decline in mental status happening over 6 months |
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At leat 2 weeks of stable mood with psychotic symptoms, plus a major depressive, manic or mixed episode |
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Fixed, persistent non bizarre belief system lasting > 1 month |
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Dissociative identity disorder |
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Multiple personality disorder History of sexual abuse |
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Persistently elevated, expansive or irritable mood lasting over 1 week |
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At least one manic or hypomanic episode *Do not use antidepressants Tx: mood stabilizers, atypical antipsychotics |
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Milder form of bipolar, lasting at least 2 years |
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Major depressive disorder |
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Self limited disorder with major depressive symptoms, lasting 6-12 months At least 5 of the symptoms for 2 or more weeks SIG E CAPS |
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Mood reactivity, reversed vegetative symptomts (hypersomnia, weight gain), leaden paralysis Most common subtype Tx: MAOIs, SSRIs |
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Maternal (postpartum) blues |
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Starts 2-3 days after delivery Usually resolves within 10-14 days Tx: supportive |
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Starts within 4 weeks of delivery, lasts 2 weeks to a year or more Tx: antidepressants, psychotherapy |
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Delusions, hallucinations, possible homicidal, suicidal attemps Lasts days to 4-6 weeks Tx: antipsychotics, antidepressants |
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Risk factors for suicide completion |
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Ethanol, sickness, no spouse, etc |
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Peaks in 10 min Tx: SSRIs, venlafaxine, benzodiazepines |
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Associated with tourette's syndrome Tx: SSRIs, clomipramine |
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Persisten reexperiencing of a traumatic event Disturbance lasts >1 month Tx: psychotherapy, SSRIs |
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Lasts between 2 days and 1 month |
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Generalized anxiety disorder |
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Uncontrollable anxiety for at least 6 months Assoc sleep disturbances, fatigue Tx: SSRI's, SNRIs |
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emotional symptoms causing impairment Lasting < 6 months |
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Physical symptoms with no identifiable physical cause. Unconcious drives |
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Multiple organ systems (at least 4 pain, 2 GI, 1 sexual, 1 pseudoneurologic) over a period of years, developing before age 30 |
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Preoccupation with minor or imagined defect in appearance Often seeks cosmetic surgery |
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Weird: Paranoid- projection major defense Schizoid- loner, voluntary withdrawal Schizotypal- Odd beliefs or magical thinking |
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Wild: Antisocial- conduct disorder for over 18yrs old Borderline- Unstable mood, self mutilation Histrionic- sexually provocative Narcissistic- Grandiosity |
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Worried: Avoidant- Hypersensitive to rejection, desires relationships OCD Dependent- submissive and clingy, low self confidence |
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Tox: GGT, AST>ALT WD: DT, use Benzos |
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Tox: Dec gag reflex, pinpoint pupils. Tx: naloxone WD: Sweating, dil pupils, flu like symptoms Tx: methadone |
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Tox: marked resp depression WD: Life threatening cardiovascular collapse |
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Tox: Ataxia, Tx: flumazenil WD: Rebound anxiety, seizure |
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Tox: Cardiac arrythmias, anxiety WD: Depression, lethargy, weight gain, HA |
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Tox: Pupillary dilation WD: increased appetite, hyper somnolence |
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Tox: Pupil dilation, sudden cardiac death Tx: benzos WD: Malaise, craving |
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Tox: Agitation, analgesia Tx: benzos, rapid acting AP WD: Depression, disturbance of thought and sleep |
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Tox: perceptual distortion |
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At risk for Hepatitis, abscess, OD, hemorrhoids, AIDS, Right sided endocarditis Tx: naloxone and buprenorphine- partial agonist, long acting with fewer WD symptoms than methadone |
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Wernicke Korsakoff Syndrome |
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Thiamine def. Confusion, opthalmoplegia, and ataxia May progress to irreversible memory loss, confabulation, personality change Replace Vit B1- Thiamine |
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Treatment for certain conditions |
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Anxiety- SSRIs, SNRIs, buspirone ADHD- Methylphenidate, amphetamines Bipolar disorder- Lithium, VPA, Carbemazapine OCD- Clomiprimine Panic disorder- venlafaxine, benzodiazepines Schizophrenia - Antipsychotics Tourette's syndrome - Antipsychotics |
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Methylpehnidate, dextroamphetamine, methamphetamine Inc catecholamines in the synaptic cleft ADHD, narcolepsy, appetite control |
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Trifluoperazine, Fluphenazine, Haloperidol "Tri to fly high" EPS side effects |
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Chlorpromazine, thiroidazine Anticholinergic, antihistamine, and a1 blockade Chlor- corneal deposits Thior - retinal deposits |
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Block dopamine D2 receptors Highly lipid soluble and stored in body fats Hyperprolactinemia from DA antagonism NMS- rigidity, myoglobinuria, autonomic instability, hyperpyrexia Tx: Dantrolene, bromocriptine |
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Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone Varied effects on serotonin, DA and a and H1 receptors Both positive and negative symptoms Olan/Cloz- significant weight gain Cloz - agranulocytosis and seizure Ziprasidone - prolong the QT |
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Mood stabilizer for Bipolar - blocks relapse and acute manic events, also SIADH Cause polyuria (AHD nephrogenic DI), teratogenesis (Ebsteins), |
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Stim serotonin Rs Generalized anxiety disorder *Takes 1-2 weeks to have an effect |
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Fluoxetine, Paroxetine, Sertraline, Citalopram Can cause GI distress, Sexual dysfunction Serotonin syndrome - (inc risk with MAOI, SNRI, TCA) Hyperthermia, confusion, myoclonus, cardiovascular collapse, flushing, diarrhea, seizures Tx: cyproheptadine |
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Venlafaxine, duloxetine, Nefazodone Depression, GAD, panic disorders Increased BP, sedation, nausea |
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Amitryptiline, doxepin, amoxepine Block reuptake of NE and serotonin Major depression, bedwetting (imipramine), OCD (clomiprimine) Sedation, atropine like side effect Convulsions, coma, cardiotoxicity (Tx with NaHCO3) |
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Trancypromine, Phenelzine, Isocarboxyzid, Selegiline Increase levels of amine NTs (NE, 5HT, DA) Use - atypical depression, anxiety, hypochondiasis Tox - hypertensive crisis with ingestion of tyramine containing foods |
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Smoking cessation Inc NE and DA Tox: stimulant effects, no sexual side effects |
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a2 antagonist - Inc release of NE and serotonin Tox- sedation, inc appetite *good for elderly and anorexics |
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Blocks NE reuptake Orthostatic htn side effect |
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Blocks serotonin reuptake Primarily for insomnia Pripaism, nausea, postural Hypotension |
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