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Step 1 - Equations
FA2012 597-598
26
Medical
Undergraduate 2
06/30/2012

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Term
Sensitivity
Definition
Sensitivity =TP/(TP+FN)
Term
Specificity
Definition
Specificity =TN/(TN+FP)
Term
Positive Predictive Value
Definition
PPV =TP/(TP+FP)
Term
Negative Predictive Value
Definition
NPV =TN/(TN+FN)
Term
Relative Risk
Definition
RR =Probability the disease is present in people with the risk/Probability the disease is present in people without the risk
Term
Attributable risk
Definition
AR =probability of disease in people with the risk - probability of disease in people without the risk
Term
Number needed to treat
Definition
NNT = 1/absolute risk reduction
Term
Number needed to harm
Definition
NNH = 1/attributable risk
Term
Hardy-weinberg equilibrium
Definition
p+q=1
p^2+2pq+q^2=1
Term
Henderson-Hasselbach equation in blood
Definition
pH = pKa + log(bicarb/[0.03*PCo2])
Term
Volume of distribution
Definition
Vd = amount of drug in body/plasma drug concentration
Term
Clearance
Definition
CL = rate of elimination of drug/plasma drug concentration
Term
Half-life
Definition
T1/2 = .7*Vd/CL
Term
Loading dose
Definition
LD = plasma concentration * Vd/F
Term
Maintenance dose
Definition
MD = plasma concentration * CL/F
Term
Cardiac output
Definition
CO = stroke * volume

CO = rate of O2 consumption/difference in arterial and venous O2 content
Term
Mean arterial pressure
Definition
MAP = CO*TPR

MAP = 1/3*systolic + 2/3*diastolic
Term
Stroke volume
Definition
SV = EDV-ESV
Term
Ejection fraction
Definition
EF = stroke volume/end diastolic volume * 100
Term
Resistance
Definition
R = driving pressure/flow

R = 8*viscosity*length/(Pi*radius^4)
Term
Net filtration pressure
Definition
Pnet = (capillary hydrostatic-interstitial hydrostatic) - (capillary oncotic-interstitial oncotic)
Term
GFR
Definition
GFR = urine[inulin]*urine flow/plasma[inulin]

GFR = clearance of inulin

GFR = Kf[(Pgc-Pbs)-(PIgc-PIbs)]
Term
Effective renal plasma flow
Definition
ERPF = clearance of PAH

ERPF = urine[PAH]*urine flow rate/plasma[PAH]
Term
Renal blood flow
Definition
RBF = RPF/(1-hematocrit)
Term
Filtration fraction
Definition
FF = GFR/RPF
Term
Physiologic dead space
Definition
Dead space = tidal volume*(Arterial CO2-Exhaled CO2)/Arterial CO2
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