Term
| Anticentromere antibodies |
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Definition
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Term
| Antidesmoglein antibodies |
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Definition
Pemphigus vulgaris
(blisters) |
|
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Term
| Anti-glomerular basement membrane antibodies |
|
Definition
Goodpasture's syndrome
(glomerulonephritis and hemotpysis) |
|
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Term
|
Definition
Drug induced SLE
(hydralazine, INH, phenytoin, procainamide) |
|
|
Term
|
Definition
RA
(systemic inflammation, joint pannus, boutonniere deformity) |
|
|
Term
| Anitmitochondrial antibodies |
|
Definition
Primary billiary cirrhosis
(female cholestasis, portal HTN) |
|
|
Term
| Antineutrophil cytoplasmic antibodies |
|
Definition
Vasculitis
(c-ANCA = Wegener's)
(p-ANCA = microscopic polyangiitis or Churg-Strauss syndrome) |
|
|
Term
|
Definition
SLE
(type 3 hypersensitivity) |
|
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Term
|
Definition
| Idiopathic thrombocytopenic purpura (ITP) |
|
|
Term
| Anti-topoisomerase antibodies |
|
Definition
| Diffuse systemic scleroderma |
|
|
Term
| anti-transglutaminase antibodies |
|
Definition
Celiac's
(diarrhea, distention, weight loss) |
|
|
Term
|
Definition
Celiac's
(diarrhea, distention, weight loss) |
|
|
Term
| Anti-endomysial antibodies |
|
Definition
Celiac's
(diarrhea, distention, weight loss) |
|
|
Term
| Apple core lesion on abdominal x-ray |
|
Definition
Colorectal cancer
(usually left sided) |
|
|
Term
| Azurophilic granular needles in leukemic blasts |
|
Definition
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|
Term
|
Definition
|
|
Term
|
Definition
| Group B, Strep Agalactiae |
|
|
Term
|
Definition
Aknylosing spondylitis
(chronic inflammatory arthritis associated with HLA-B27) |
|
|
Term
| Basophilic nuclear remnants in RBCs |
|
Definition
Howell-Jowell bodies
(due to splenectomy of nonfunctional spleen) |
|
|
Term
| Basophilic stippling of RBCs |
|
Definition
Lead poisoning
Sideroblastic anemia |
|
|
Term
|
Definition
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|
Term
| Boot shaped heart on x-ray |
|
Definition
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|
Term
| Branching gram positive rods with sulfur granules |
|
Definition
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|
Term
| Bronchogenic apical lung tumor |
|
Definition
Pancoast tumor
(compression of sympathetic ganglion causing Horner's) |
|
|
Term
|
Definition
Hyperparathyroidism
Osteitis fibrosa cystica
(Hemorrhage (hemosiderin) causes brown color of osteolytic cysts) |
|
|
Term
| Cardiomegaly with apical atrophy |
|
Definition
Chagas disease
(Trypanosoma cruzi) |
|
|
Term
| Cellular crescents in Bowman's capsule |
|
Definition
| Rapidly progressive crescentic glomerulonephritis |
|
|
Term
|
Definition
Endometriosis
(frequently both ovaries) |
|
|
Term
| Circular grouping of dark tumor cells surrounding pale neurofibrils |
|
Definition
Neuroblastoma
Medulloblastoma
Retinoblastoma
(Homer Wright Rosettes) |
|
|
Term
| Colonies of mucoid Pseudomonas in lungs |
|
Definition
Cystic Fibrosis
(autosomal recessive mutation in CFTR) |
|
|
Term
| Decreased AFP in amniotic fluid/maternal serum |
|
Definition
Down's syndrome
Other chromosomal abnormality |
|
|
Term
| Degeneration of dorsal column nerves |
|
Definition
Tabes Dorsalis
(Tertiary Syphilis) |
|
|
Term
| Depigmentation of neurons in substantial nigra |
|
Definition
|
|
Term
| Desquamated epithelium casts in sputum |
|
Definition
Curschmann's spirals
(bronchial asthma) |
|
|
Term
| Disarrayed granulosa cells in eosinophilic fluid |
|
Definition
Call-exner bodies
(granulosa-theca cell tumor of ovary) |
|
|
Term
| Dysplastic squamos cervical cells with nuclear enlargement and hyperchromasia |
|
Definition
Koilocytes of HPV
(increased risk of cervical cancer) |
|
|
Term
| Enlarged cells with intranuclear inclusion bodies |
|
Definition
|
|
Term
| Enlarged thyroid cells with ground-glass nuclei |
|
Definition
Papillary carcinoma
(orphan annie eye nuclei) |
|
|
Term
| Eosinophilic cytoplasmic inclusion in liver cells |
|
Definition
Mallory Bodies
(Alcoholic liver disease) |
|
|
Term
| Eosinophilic cytoplasmic inclusion in nerve cells |
|
Definition
Lewy Body
(Parkinson's disease) |
|
|
Term
| Eosinophilic globule in liver |
|
Definition
Councilman body - Apoptosis
(toxic or viral hepatitis/yellow fever) |
|
|
Term
| Eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells |
|
Definition
|
|
Term
| Extracellular amyloid deposition in gray matter of brain |
|
Definition
Senile plaques
(Alzheimer's) |
|
|
Term
| Gint B cells with bilobed nuclei and prominent inclusions |
|
Definition
Reed-Sternberg cells
(Hodgkin's Lymphoma) |
|
|
Term
| Glomerulus-like structure surrounding vessel in germ cells |
|
Definition
Yolk sac tumor
(Schiller-Duval body) |
|
|
Term
| Hair on end (crew cut) appearance on x-ray |
|
Definition
Beta thalassemia
sickle cell anemia
(marrow expansion) |
|
|
Term
|
Definition
Choriocarcinoma
Hydatidiform mole (partial or complete) |
|
|
Term
| Granulomatous heart nodules |
|
Definition
Aschoff bodies
(Rheumatic fever) |
|
|
Term
|
Definition
|
|
Term
| Hexagonal, double pointed, needle-like crystals in bronchial secretions |
|
Definition
Bronchial asthma
(Charcot-Leyden crystals, eosinophilic granules) |
|
|
Term
|
Definition
|
|
Term
Hilar lymphadenopathy
peripheral granulmatous lesion in middle or lower lung lobes (with or without calcification) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Hypersegmented neutrophils |
|
Definition
Megaloblastic anemia
B12 if neuro symptoms
Folate if no neuro |
|
|
Term
| Hypchromic microcytic anemia |
|
Definition
Iron deficiency
Lead poisoning
Thalassemia |
|
|
Term
| Increased AFP in amniotic fluid/maternal serum |
|
Definition
Dating Error
Neural tube defect (anencephaly, spina bifida) |
|
|
Term
| Increased uric acid levels |
|
Definition
Gout
Lesch-Nyan syndrome
Tumor Lysis syndrome
Loop diuretics
Thiazide diuretics |
|
|
Term
| Intranuclear eosiniophilic droplet like bodies |
|
Definition
HSV
CMV
(Cowdry type A bodies) |
|
|
Term
| Iron-containing nodules in alveolar septum |
|
Definition
Ferruginous bodies
(Asbestosis, increased risk of mesothelioma) |
|
|
Term
Large lysosomal vesicles in phagocytes
immunodeficiency |
|
Definition
Chediak-Higashi
(congenital failure of phagolysosome formation) |
|
|
Term
| Lead pipe appearance of colon on x-ray |
|
Definition
Ulcerative colitis
(loss of haustra) |
|
|
Term
| Linear appearance of glomeruli on immunofluorescence |
|
Definition
|
|
Term
|
Definition
Wilson's disease
(hepatolenticular degeneration) |
|
|
Term
| Lumpy bumpy appearance of glomeruli on immunofluoresence |
|
Definition
Poststreptococcal glomerulonephritis
(immune complex deposition of IgG and C3b) |
|
|
Term
| Lytic (hole punched) bone lesions on x-ray |
|
Definition
|
|
Term
| Mammary gland (blue domed) cyst |
|
Definition
| Fibrocystic change of the breast |
|
|
Term
| Monoclonal antibody spike |
|
Definition
Multiple Myeloma (IgG or IgA)
Monoclonal gammopathy of undetermined significance
Waldenstrom's Macroglobulinemia (IgM)
Primary Amyloidosis |
|
|
Term
| Monoclonal globulin protein in blood/urine |
|
Definition
Kappa/Lambda chains: Multiple Myeloma
Igm: Waldenstrom's macroglobulinemia
(bence-jones proteins) |
|
|
Term
| Mucin filled cell with peripheral nucleus |
|
Definition
Signet ring
(gastric carcinoma) |
|
|
Term
| Needle-shaped, negatively birefringent crystals |
|
Definition
|
|
Term
| Nodular hyaline deposits in glomeruli |
|
Definition
Diabetic nephropathy
(Kimmelstiel-Wilson nodules) |
|
|
Term
|
Definition
|
|
Term
|
Definition
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|
Term
|
Definition
| Chronic passive congestion of liver from right heart failure |
|
|
Term
| Onion skin periosteal reaction |
|
Definition
Ewing's Sarcoma
(malignant round cell tumor) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Periosteum raised from bone creating a triangle |
|
Definition
Osteosarcoma
Ewing's Sarcoma
Pyogenic Osteomyelitis
(Codman's triangle) |
|
|
Term
|
Definition
Minimal Change disease
(child with nephrotic syndrome) |
|
|
Term
| Polished ivory like appearance of bone at cartilage erosion |
|
Definition
Eburnation
(osteoarthritis resulting in bony sclerosis) |
|
|
Term
| Protein aggregates in neurons from hyperphosphorylation of protein tau |
|
Definition
Alzheimer's
CJD
(Neurofibrillary tangles) |
|
|
Term
| Pseuopalisading tumor cells on brain biopsy |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Rectnagular, crystal like, cytoplasmic inclusions in Leydig cells |
|
Definition
Leydig Cell tumor
(Reinke crystals) |
|
|
Term
| Renal epithelial casts in urine |
|
Definition
| Acute toxic/viral nephrosis |
|
|
Term
Rhomboid crystals
positively birefringent |
|
Definition
Pseudogout
(calcium pyrophosphate dihydrate) |
|
|
Term
|
Definition
|
|
Term
| Ring enhancing brain lesion in AIDS |
|
Definition
|
|
Term
| Sheets of medium sized lymphoid cells with starry sky appearance |
|
Definition
Burkitt's lymphoma
(8:14, EBV) |
|
|
Term
| Silver staining spherical aggregation of tau proteins in neurons |
|
Definition
Pick's Disease
(Progressive dementia with changes in personality) |
|
|
Term
| Soap bubble in femur or tibia on x-ray |
|
Definition
Giant cell tumor of bone
(usually benign) |
|
|
Term
Spikes on basement membrane
dome like sub epithelial deposits |
|
Definition
Membranous glomerulonephritis
(may progress to nephrotic syndrome) |
|
|
Term
| Stacks of red blood cells |
|
Definition
High ESR
Multiple Myeloma
(rouleaux formation) |
|
|
Term
| Stippled vaginal epithelial cells |
|
Definition
Gardnerella Vaginalis
(clue cells) |
|
|
Term
| Tennis tacket shaped cytoplasmic organelles in langerhans cels |
|
Definition
Bierbeck granules
(Histocytosis X, eosinophilic granuloma) |
|
|
Term
| Thrombi made of white/red layers |
|
Definition
Lines of Zahn
(arterial thrombus with layers of platelets/RBCs) |
|
|
Term
| Thumb sign on lateral x-ray |
|
Definition
Epiglottits
(Haemophilus influenza) |
|
|
Term
| Thyroid like appearance of kidney |
|
Definition
| Chronic bacterial pyelonephritis |
|
|
Term
| Tram-track appearance on LM |
|
Definition
| Membranoproliferative glomerulonephritis |
|
|
Term
| Triglyceride accumulation in liver cell vacuoles |
|
Definition
Fatty liver disease
(alcoholic or metabolic syndrome) |
|
|
Term
|
Definition
|
|
Term
| Wire loop glomerular appearance on LM |
|
Definition
|
|
Term
|
Definition
Xanthochromia
(previous subarachnoid hemorrhage) |
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|
