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Staphylocci
BBD exam 1: 3/23
20
Medical
Professional
04/10/2010

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Cards

Term
what is the shape and gram stain of S. aureus?
Definition
gram+ cocci
Term
what is protein A?
Definition
Inhibits antibody-mediated clearance by binding Ig Fc receptors
Term
what virulence factors does it use to ahere and bind to the body?
Definition
clumping, fibronectin-binding, collagen-binding factors
Term
what virulence factors does it use to ahere and bind to the body?
Definition
clumping, fibronectin-binding, collagen-binding factors
Term
what is an example of a membrane-activating agent?
Definition
Cytotoxins.
Term
what is an example of a membrane-activating agent?
Definition
Cytotoxins.
Term
what is the function of cytotoxins?
Definition
destroy cells. some big ones used are alpha, beta, delta, gamma, leukocidin.
Term
what is a superantigen?
Definition
a molecule (such as staphylococcal exotoxin) that can short-circuit the normal sequence of events leading to activation of helper T cells
Term
what is "pyrogenic"?
Definition
causes fever
Term
name a pyrogenic toxin used by S. aureus
Definition
staphyloccal enterotoxin
Term
Exfoliative (epidermolytic) toxin causes what syndrome?
Definition
Staphylococcal Scalded Skin Syndrome (SSSS)
Term
what toxin causes Toxic Shock Syndrome?
Definition
Toxic Shock Syndrome Toxin-1 (TSST-1)
Term
Coagulase, Staphylokinase, Hyaluronidase, Lipases, Proteases, Nucleases, Catalse, Penicillinase; are all examples of what?
Definition
Enzymes produced by Staph that contribute or lead to disease.
Term
what are some routes of transmission?
Definition
person-to-person, food poisoning (most cases are self-limiting), aspiration of oral secretion
Term
what is impetigo?
Definition
cutaneous infection with pus-filled vesicles. Often presenting on face and limbs
Term
what is folliculitis?
Definition
impetigo involving hair follicles
Term
what are furuncles?
Definition
boils. large painful pus-filled cutaneous nodules
Term
what are carbuncles?
Definition
collection of furuncles with extension into SubQ
Term
can it cause endocarditis
Definition
YES. (future PBL case.)
Term
what is the treatment for S. aureus?
Definition
glycopeptide-Vancomycin. It's resistant to penicillins.
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