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Squilly's "Pallette"
pharmaceutical excipients Ceutics 2 and compounding
9
Pharmacology
Undergraduate 4
08/31/2012

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Cards

Term
Lactose (spray Dried)
Definition

Solid Diluent

 

Uses: 

  • spray dried anhydrous type is used in direct compression formulas. 
  • generally an ingredient of the medium used in penicillin production. 
  • extensively used as an addition to milk for infant feeding
Solubility:
  • 1 g in 5mL water or 2.6 mL boiling water
  • very slightly soluble in alcohol
  • insoluble in chloroform or ether
Term
Glycerin 
Definition

Liquid Diluent 

 

the simplest trihydric alcohol.

  • very valuable in pharmacy because of it ssolvent property
  • humectant: keeps substances moist because of its hygroscopicity
  • high viscosity
  • if triturated with strong oxidiing agents , an explosion may occur 
  • forms a complex with boric acid or sodium borate producing an acid
  • miscible with water, alcohol, or methanol 
  • insoluble in chloroform, ether, or fixed and volatile oils  

Term
propylene glycol 
Definition

Liquid diluent 

  • viscous
  • absorbs moisture from moist air
  • miscible with water, alcohol, acetone, or chloroform
  • suluble in ether
  • dissolves volatile oils 
  • immiscible with fixed oil
  • can also be used as a preservative and humectant 
Term
polyethylene glycol 
Definition

liquid diluent

 

  • dissolve in water to form clear solutions 
  • soluble in many organic solvents 
  • wide range of solubilities and compatibilities 
  • used in lotions
Term
Calcium Carbonate 
Definition

Solid Diluent

  • practically insoluble in water 
  • solubility in water is increased by the presence of an ammonium salt or carbon dioxide
  • insoluble in alcohol
  • dissolves with effervescence in dilute acetic, hydrocloric, or nitric acids 
  • rapidly acting non systemic antacid 

Term
magnesium oxide 
Definition

Solid Diluent 

 

  • bulky (light) or dense (heavy) powder
  • high temperature syield more compact forms
  • absorbs moisture and carbon dioxide when exposed to air
  • insoluble to water, alkaline reaction in water
  • insoluble in alchol
  • soluble in dilute actives
  • fairly long acting non systemic antacid 

Term
Starch 
Definition

Solid Diluent 

  • irregular, angular white masses or fine powder
  • insoluble in cold water. when boiled with 20 times its weight of hot water then cooled, a translucent whitish jelly results 
  • absorbent and demulcent properties
  • dusting powder 
  • filler, binder, disintegrant
Term
Talc
Definition

Solid diluent 

  • dusting powder to make suppositories
  • used as filtration medium for clarifying liquids
  • lubricant in the manufacture of tablets

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