Term
| alcohol mechanism of action |
|
Definition
| CNS depressant (GABAergic) |
|
|
Term
|
Definition
| increase dopamine release and reuptake |
|
|
Term
|
Definition
tachycardia
pupil DILATION
..."strung out"
formication (sensation of bugs on skin) |
|
|
Term
|
Definition
withdrawal is not medically dangerous
no specific, well-established treatments |
|
|
Term
|
Definition
*arrthmias, MI, cardiorespiratory arrest
*cerebral hemorrhage
*convulsions
*spontaneous abortion
*psychosis |
|
|
Term
| cannabis pharmacokinetics |
|
Definition
long elimination halflife
onset & peak much quicker when smoked
THC binds to cannabinoid receptors in the brain |
|
|
Term
|
Definition
mostly psychologic
insomnia, restlessness, irritability... |
|
|
Term
|
Definition
more carcinogenic than tobacco
pharyngitis, bronchitis
low-T
low sperm coutns
amotivational syndrome |
|
|
Term
|
Definition
| bind to specific Mu opioid receptors in the CNS and PNS |
|
|
Term
|
Definition
| analgesia, euphoria, decreased anxiety, respiratory depression (death in OD), inhibition certain spinal reflexes, decreased GI motility, suppress cough, PINPOINT pupils, pruritis, nausea, vomititng |
|
|
Term
|
Definition
painful
dilated pupils
need pharm intervention; effort to avoid w/drawal powerful motive to use |
|
|
Term
| opiate withdrawal treatment |
|
Definition
-treat symptoms
-BDZ, plus Clonidine
-Buprenorphine
-longer acting opioids
-ultra rapid detox (uncommon) |
|
|
Term
|
Definition
| serotonergic receptor agonists |
|
|
Term
|
Definition
-rapid onset of mood/cog/perceptual alterations
p-pupil DILATION, tachycardia, palpitations, blurred visions, tremors, incoordination
-memory is preserved |
|
|
Term
|
Definition
-none reported for most
-supportive care, psychological support
-possible "hangover" with MDMA/ecstasy (headache, fatigue, sore jaw muscles) |
|
|
