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Small Animal Gastroenterology
Exam 1: Lectures 1-17
51
Veterinary Medicine
Graduate
10/01/2012

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Term
List the Clinical Signs associated with oropharyngeal dysphagias
Definition
salivation, gagging, dropping food, difficulty swallowing
Term
Describe the differences between anatomic and functional oropharyngeal dysphagias
Definition
Anatomic: interferes w/ swallowing

Functional: failure to contract/ initiate peristalsis
Term
How do you DIAGNOSE (medically investigate) oropharyngeal dysphagia
Definition
PE, oral exam, survey radiographs, videofluoroscopy
Term
List supportive TREATMENT options for oropharyngeal dysphagia
Definition
Nutrition
Term
What are oropharyngeal dysphagias?
Definition
Term
What is cricopharyngeal achalasia?
Definition
Term
Describe the PATHOGENESIS of cricopharyngeal achalasia
Definition
hypertensive gastroesophageal sphincter, inadequate relaxation
Term
How would you TREAT cricopharyngeal achalasia?
Definition
surgical myotomy
Term
Describe Primary vs. Secondary Peristalsis
Definition
Primary: food bolus moved down esophagus

Secondary: secondary wave of contractions
Term
List some CLINICAL SIGNS of esophageal motility disorders
Definition
regurgitation, odynophagia, dysphagia, increased salivation, change in appetite,
Term
Describe the SPECIES DIFFERENCES in esophageal anatomy and physiology
Definition
Canine: all striated muscle; lacks 5-HT4 receptors

Feline: smooth muscle in distal 1/2 to 1/3
Term
What is Esophageal Stricture?
Definition
Term
Describe the PATHOGENESIS of esophageal stricture
Definition
cats: doxycycline can cause esophagitis leading to scarring and subsequent stricture formation
Term
How would you TREAT/MANAGE esophageal strictures?
Definition
mechanical dilation
Term
List some CONGENITAL disorders of the esophagus.
Definition
hiatal hernia, vascular ring anomaly, megaesophagus, fistula
Term
List the 4 components of esophagitis THERAPY
Definition
1. sucralfate
2. decrease acid in stomach (ie-famotidine)
3. corticosteroids oral
4. +/- local injection of corticosteroids
Term
What is a hiatal hernia?
Definition
Term
Compare & Contrast medical vs surgical treatment for hiatal hernias
Definition
Medical: start with this; can advance to surgery if necessary

Surgery: usu. necessary in cases involving laryngeal paralysis
Term
What is canine idiopathic megaesophagus?
Definition
Term
Describe the pathogenesis of canine idiopathic megaesophagus (myasthenia vs afferent neural pathway)
Definition
Term
How would you treat canine idiopathic megaesophagus? (myasthenia vs. afferent neural pathway)
Definition
Term
How would you DIAGNOSE esophageal neoplasia?
Definition
Survey Radiographs
Ultrasound
Term
How would you TREAT esophageal neoplasia?
Definition
Chemo, radiation

Surgery not usually a good option
Term
Describe the general principles of endoscopy- Best Practice Standards
Definition
don't bend/force/torque; don't advance blindly; position centrally; insufflate; biopsy; know landmarks
Term
Describe esophageal endoscopy principles
Definition
withhold food 12hrs; no atropine/opioids; general anesthesia; left lateral recumbency; use bite block
Term
Describe gastric endoscopic principles
Definition
withhold food 12hrs; no atropine/opioids; general anesthesia; left lateral recumbency; use bite block
Term
Describe intestinal endoscopy principles
Definition
can only access duodenum from stomach
Term
Describe colonic endoscopy principles
Definition
withhold food 36-48hrs, warm water enema, oral electrolyte solution (12hrs prior), general anesthesia, left lateral recumbency, can see cecum and distal ileum as well
Term
Give some examples of endoscopic interventional procedures
Definition
PEG tube (percutaneous endoscopic tube gastrotomy) placement
- indicated in anorectic,
malnourished, or dysphagic
animals
Term
List the Advantages & Disadvantages of endoscopy vs exploratory surgery
Definition
Endoscopy:
Pros: less invasive, direct
visualization, need multiple
biopsies
Cons: only duodenum; small biopsies

Surgery:
Pros: full thickness biopsy,
inspect other organs
Cons: increased risk, longer
recovery
Term
Describe patient positioning for upper and lower GI endoscopy
Definition
left lateral recumbency
Term
Describe appropriate patient PREPARATION (ie- pre-op meds)
Definition
(see other slides)
Term
What are the differences b/w fiberoptic and digital image endoscopy?
Definition
fiberoptic: fiber bundles-> image-> eyepiece; cheaper; less clear picture

Digital: computer microchip-> image-> TV; expensive; clearer picture
Term
Compare & Contrast anatomic (outflow obstruction) vs. functional (delayed gastric emptying) disorders
Definition
Term
List the CLINICAL SIGNS assoc. w/ gastric disease
Definition
Term
How would you DIAGNOSE (or medically investigate) gastric disease?
Definition
Term
How would you TREAT anatomic outflow obstruction?
Definition
Term
Describe how you would nutritionally manage delayed gastric emptying disorders
Definition
low fat, low protein, neutral pH, low osmolality, liquid
Term
List the categories (or where the various drugs act) for GI prokinetic therapy
Definition
- Dopamine D2 antagonists
- 5-HT4 serotonergic agonists
- motilin agonists
- acetylcholinesterase inhibitors
Term
Give an example of Dopamine D2 antagonists
Definition
Term
Give an example of 5-HT4 serotonergic agonists
Definition
Term
Give an example of motilin agonists
Definition
Term
Give an example of acetylcholinesterase inhibitors
Definition
Term
Name the Salivary glands (dog & cat)
Definition
Parotid salivary gland (serous)
Mandibular salivary gland (seromucus)
Sublingual salivary gland (seromucus)
zygomatic salivary gland (seromucus)

molar salivary gland (cats only)(seromucus)
Term
List some differentials for maxillofacial and cervical swellings
Definition
edema (hypersensitivity rxn, lymphatic obstruction, vasculitis, cardiovascular abnormalities), salivary pathology, trauma, infection (abscess), FB, autoimmune conditions (masticatory myositis), developmental anomalies (brachial cyst), neoplasia, periostitis ossificans, cranial mandibular osteopathy, subcutaneous emphysema (tracheal rupture, pneumothorax/ pneumomediastinum)
Term
What is a sialocele?
Definition
accumulations of saliva in the regional soft tissue; most common salivary pathology in the dog and cat

Parotid gland -> sialocele
other salivary glands-> mucocele

Types: ranulas (sublingual mucocele), pharyngeal mucocele, cervical mucocele
Term
Describe the pathogenesis of sialoceles
Definition
secondary to trauma, anatomical defec, iatrogenic trauma, obstruction

non-painful and soft, but firm

swelling size may increase or decrease over time
Term
Are sialoceles cyts?
Definition
NO

cysts: epithelial lining
sialocele: lined by granulation tissue
Term
How would you diagnose sialoceles?
Definition
clinical suspicion, rule out other diseases/abscesses/FB/draining tracts

aspirating a yellow-blood tinged thick fluid

periodic-acid schiff stain
Sialography
advanced imaging
Term
How would you treat sialoceles?
Definition
remove the offending salivary gland and duct

trx of the fluid accumulation: benign neglect, aspiration, surgical resection, marsupialization
Term
Contrast retrobulbar abscess/cellulitis vs masticatory myositis
Definition
Key point:
first thing to do is give
analgesia/sedation and try to open
mouth

if mouth opens...then think retrobulbar abscess/cellulitis

if mouth does not open...masticatory myosistis
- auto-imune dz (type 2M myofibers)

Treatment:
masticatory myositis: immunosuppressive steroids
retrobulbar abscess: antibiotics
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