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Sleep (oct 9 and onward!)
Sleep
35
Physiology
Undergraduate 2
10/27/2008

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Cards

Term
EMG (Electromyograph)
Definition
Measures Muscle Tone during sleep
Term
EEG (electroenecephalograph) + diff't brain waves
Definition
Summated brain wave activity
Term
Alpha Waves
Definition
waves that appear eyes closed: (8-12 Hz) - high amp with low frequency
Term
Beta Waves (as in you beta be awake!)
Definition
waves that appear during wakefulness; (13-30 Hz): low amplitude, high frequency)
Term
STAGES OF SLEEP!
Definition
I: Light Sleep, theta waves
II: K complexes, sleep spindles
III: quiet
IV: lower heartrate lower blood pressure, lower bodytemp
V: REM, loss muscle tone, sympathetic activity
Term
Gross Mov't every:
Definition
20 minutes
Term
move through all stages of sleep in:
Definition
30-45 min
Term
90 minutes after sleep onset
Definition
Rem + sympathetic activation start
Term
Seven Changes in REM sleep
Definition
1. EEG is similar to awake "non" pattern: desynchornized, low voltage. 2. Increased sympathetic activity (heart rate, blood pressure) 3. Rapid Eye Mov't starts. 4. PGO waves 5. Loss of muscle tone 6. Vivid, episodic dreams 7. Signs of sexual arousal
Term
PGO spikes
Definition
Pons- Geniculate nucleus - Occipital Cortex spikes: predict onset of REM
Term
Function of Sleep
Definition
is it a way to stay away from preditors? Brain activity is only reduced a little...
Term
Sleep Deprivation
Definition
creates ulcers, increased activity, death, feeling of helplessness
Term
SWS - function of
Definition
this type of sleep is involved with restoration, recovering & unlearning
Term
REM (functions)
Definition
This type of sleep is a period of integration of neural activity with previous experiences: this is why infants spend more time in this type of sleep (80%)
Term
Ascending Reticular Activating System - "Reticular Formation"
Definition
this system alerts to new, diff't stimulus, and if you damage this area, it increases SWS. Also, if you electrically stimulate the RF, arousal is induced.
Term
sleep is not due to chemical control
Definition
this is proven by dolphin's having two hemispheres asleep at same time and siamese twins sleeping separately
Term
neuroepinephrine & diff't activity patterns
Definition
this neurotransmitter is found in the Locus coeruleus: it has high activity during wakefulness and low activity during SWS and no activity during REM
Term
AcH & inhibitor & activity pattern
Definition
this neurotransmitter inhibits muscle mov't during sleep, is inhibited by serotonin. It is found in the PONS and from there regulates the shift into REM (more of it = more REM)
Term
GABA
Definition
this is an interneuron b/t all brain areas of sleep.... can be enhanced by valium
Term
Orexin
Definition
this is a peptide involved with narcolepsy
Term
Ventrolateral Preoptic Area
Definition
this junction b/t the hypothalamus & the basal forebrain, once damaged, leads to total insomnia. If electrically stimulated, it will produce sleepyiness
Term
adenosine
Definition
these neurons usually put us to sleep, are blocked by caffeine and associated with ventrolateral preoptic area
Term
Pons & sleep
Definition
this area of the brain starts PGO waves, and therefore regulate shift into REM. See AcH
Term
cholinergic neurons
Definition
"REM-on" neurons, found in pons... when entering rem, activity goes up
Term
noradrenegetic + serotonergic neurons
Definition
"REM-off" - in locus coeruleus & raphé nuclei
when exiting REM, these two types of neurons go up
Term
Insomnia
Definition
12% of population - can be situational, drug induced (overuse of sleeping pills), sleep apnea (person stops breathing)
Term
Narcolepsy: two types
Definition
two types of this are sleep attacks (urge to sleep during day) & cataplexy (sudden REM paralysis)
Term
hypocretin
Definition
deficits in this type of hypothalamic neuropeptide is linked to narcolepsy
Term
sleep behavior disorder
Definition
this disorder is when people act out their dreams: "REM w/o Atonia"
Term
Fatal Familial Insomnia
Definition
this disorder is when ppl can't go to sleep at all and die after about a year
Term
Circadian Rhythms
Definition
1 cycle of this is about a day: 24 hours
Term
light resets...
Definition
circadian rhythm is reset by...
Term
Suprachaismatic Nucleaus
Definition
this nucleus is the bioclock, which governs some circadian rhythms; it is involved with melotonin, and neurons from the optic nerve synapse there
Term
Where does SCN recieve input from
Definition
This nucleus recieves input from ganglion cells in retina (reset biorhythm) and lateral genicluate nucleus of the thalamus
Term
Zeitgeber
Definition
this function involves how light resets the biorhythm, and how ppl placed in bunkers run at later and later rhythm of ~ 25 hours
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