Shared Flashcard Set

Details

Skin/ integument drugs
Pharmacology
75
Veterinary Medicine
Not Applicable
07/07/2020

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Cards

Term
layers of the integumentary system
Definition
epidermis

dermis

hypodermis
Term
functions of integumentary system
Definition
protection

temperature regulation

nociception - touch sensation

produce vitamin d

excrete certain substances
Term
increase in the amount of skin scaling
Definition
sebborhea
Term
stimulate horny later to listen or separate
Definition
keratolytics
Term
encourages normal development if keratin
Definition
keratoplastic
Term
also has increase in oil production with scaling
Definition
sebborhea olesa
Term
topical antiseborrhetics
Definition
sulfur

salacylic acid

benzoyl peroxide
Term
functions if sulfur
Definition
keratolytic, keratoplastic, antipruritic, antibacterial, antifungal, antiparasitic, mild follicular flusher
Term
functions if salacylic acid
Definition
keratoplastic, keratolytic, antipruritic, antibacterial
Term
functions if benzoyl peroxide
Definition
keratolytic, antipruritic, follicular flushing, degreaser, antibacterial
Term
4 stages of wound healing
Definition
inflammatory - hemmorage, vasoconstriction.

debridement - neutrophils and macrophages (6 hours)

repair - blood clot (3-5 days). collagen, granulation

maturation - remodeling, strengthening
Term
healing times affected by?
Definition
size, location of wound
age
nutrition
Term
principles of wound care
Definition
clip and clean
debride if needed
protect
topical antibacterials
ointments, creams, sprays, powders
Term
5 layers of epidermis
Definition
basal (stratum basale)(deepest)
spinous (stratum spinosum)
granular (stratum granulosum)
clear (stratum lucidum)
and horny/cornified (stratum corneum) - superficial layer
Term
dermis contains what structures
Definition
collagen fibers, blood vessels, nerves, lymphatics, and other structures such as hair follicles, sebaceous glands, and sweat glands
Term
hypodermis comprised of
Definition
fat and connective tissue
Term
common ingredients of topical antiseborrheics
Definition
topical essential fatty acids

Phytosphingosine

Selenium sulfide

Salicylic acid

Precipitated sulfur

coal tar

benzoyl peroxide
Term
Burow's solution. This is an astringent solution and an antipruritic agent that is useful for the treatment of superficial skin problems. It can be used to help with acute moist dermatitis, fold dermatitis, and contact dermatitis. Some doctors may use it to treat otitis externa. The exact manner in which this agent works is not fully known at this time.
Definition
Topical Aluminum Acetate Solution
Term
used topically as both an antiinflammatory and antipruritic agent. At this time, however, scientists are concerned about its mechanism of action. It is thought that perhaps it inhibits prostaglandin production.
Definition
topical colloidal oatmeal
Term
commonly used for their antipruritic and antiinflammatory properties. They tend to help skin problems such as atopic dermatitis, sebaceous adenitis, and seborrhea. Some of these products have natural oils in them, which also may help skin problems. affect arachidonic acid levels and also affect the production of prostaglandins in the body, which can reduce inflammation and pruritus. also help to create healthy skin.
Definition
topical essential fatty acids
Term
first-generation antihistamine that has some local anesthetic properties. This drug can be absorbed transdermally but not enough to cause systemic effects.
Definition
topical diphenhydramine
Term
can be applied topically as a skin anesthetic and also helps with pruritus. It may be used to treat acute moist dermatitis, pruritic lesions, or painful skin conditions.
Definition
topical lidocaine/ prilocaine
Term
useful in treating localized inflammatory and pruritic cases such as atopic dermatitis. It can also be sprayed on sutures postoperatively to aid in the wound healing process.
Definition
topical Phytosphingosine
Term
has the ability to cause surface and local anesthetic characteristics, which can affect the peripheral nerves. It may be combined with other products to reduce pain or itching. At this time, scientists are unclear of this drug's mechanism of action.
Definition
Topical Pramoxine hcl
Term
used in equines for overexertion, soreness, or stiffness.
Definition
Topical Phenol, Menthol, camphor
Term
can be used for mild itching, mild bacterial infections, and dry skin. It works well for relief from insect bites, acute moist dermatitis, acral lick dermatitis, fold dermatitis, feline acne, and postsurgical wounds. The exact mechanism of action is unclear at this time. has antiseptic and astringent ability.
Definition
Topical Neutralized zinc gluconate
Term
useful in the treatment of localized pruritus and/or inflammatory conditions. Because topically applied corticosteroids reduce the ability of leukocytes and macrophages to attack infected skin, the area to which such agents are applied will have less redness, itching, and swelling.
Definition
topical hydrocortisone
Term
This is a high-potency topical corticosteroid. It is used in the treatment of otic or skin itching or inflammation that may be associated with bacterial infections. These products should be used as a last resort because the risks associated with them are greater than those with hydrocortisone.
Definition
Topical Isoflurpredone acetate
Term
useful in the treatment of itching and inflamed skin that may be associated with bacterial or yeast infections. When hydrocortisone products do not produce desirable results, this may be used.
Definition
Mometasone furoate
Term
useful as an adjunct in the treatment of pruritus. It is best suited for small lesions that only need to be treated for a short duration.
Definition
triamcinolone acetonide
Term
An agent that causes contraction after application to tissue.
Definition
astringent
Term
astringent examples
Definition
Aluminum Acetate Solution

Topical Neutralized Zinc Gluconate
Term
topical corticosteroids
Definition
hydrocortisone

betamethasone - use last

Isoflurpredone acetate - use last

Mometasone furoate

Triamcinolone Acetonide
Term
topical antipruritics
Definition
Aluminum Acetate Solution

colloidal oatmeal

essential fatty acids

diphenhydramine

lidocaine/ prilocaine

Phytosphingosine

Pramoxine hcl

Phenol, Menthol, camphor

Neutralized zinc gluconate
Term
astringent solution and an antipruritic agent that is useful for the treatment of superficial skin problems. It can be used to help with acute moist dermatitis, fold dermatitis, and contact dermatitis. Some doctors may use it to treat otitis externa.
Definition
Aluminum Acetate Solution
Term
skin antiseptics
Definition
Acetic Acid/Boric Acid

chlorhexidine

chloroxylenol

Neutralized Zinc Gluconate
Term
substance used on the skin to prevent the growth of bacteria or to provide preoperative cleansing of the skin.
Definition
antiseptic
Term
are used to treat skin infections caused by Staphylococcus spp., Pseudomonas spp., and Malassezia spp.
Definition
acetic acid/ boric acid
Term
may be easier on patients who are unable to tolerate benzoyl peroxide. It may have residual effects and can remain active on the skin after rinsing. is used as a topical antiseptic. It does not seem to have much efficacy against Pseudomonas or Serratia spp.
Definition
chlorhexidine
Term
known as p-chloro-m-xylenol (PCMX). It is an antimicrobial disinfectant that is effective against gram-negative and gram-positive bacteria. It is also effective against RNA and DNA viruses. It may be used as a preoperative scrub of the skin, for cleaning wounds, for the treatment of bacteria and fungi, and for the treatment of yeast infections.
Definition
chloroxylenol
Term
chemical system composed of a continuous medium throughout which small particles are distributed and do not settle out under the influence of gravity
Definition
collagen
Term
A plug of keratin and sebum within a hair follicle of the skin.
Definition
comedo
Term
Inflammation of the skin
Definition
dermatitis
Term
Fungi parasitic on the skin.
Definition
dermatophyte
Term
A fungal skin infection.
Definition
dermatophytosis
Term
Redness of the skin caused by congestion of the capillaries.
Definition
erythema
Term
Organic compound of carbon, hydrogen, and oxygen that is esterified with glycerol to form fat.
Definition
fatty acid
Term
A focal suppurative inflammation of the skin and subcutaneous tissue; also known as a boil.
Definition
furuncle (furunculosis)
Term
New tissue formed in the healing of wounds of the soft tissue, consisting of connective tissue cells and ingrown young vessels; it ultimately forms a scar.
Definition
granulation tissue
Term
Pertaining to, or composed of, skin.
Definition
integumentary system
Term
An agent that promotes loosening or separation of the horny layer of the epidermis.
Definition
keratolytic
Term
An agent that promotes normalization of the development of keratin.
Definition
keratoplastic
Term
Itching
Definition
pruritis
Term
A severe acute inflammation of the bowel mucosa
Definition
Pseudomembranous colitis
Term
Any skin disease characterized by the presence or formation of pus.
Definition
pyoderma
Term
An increase in scaling of the skin; sebum production may or may not be increased.
Definition
sebborhea
Term
Condition characterized by scaling and excess lipid production that forms brownish yellow clumps, which adhere to the hair and skin.
Definition
Seborrhea oleosa
Term
Characterized by dry skin and white to gray scales that do not adhere to the hair or skin.
Definition
Seborrhea sicca
Term
topical antifungals
Definition
enilconazole

ketoconazolelime sulfur

miconazole

Nystatin
selenium sulfide
terbenfine hcl
salacylic acid
precipitated sulfur
coal tar
Term
for dermatophytes in horses
Definition
enilconazole
Term
antifungal for dermatophytes and yeast
Definition
ketoconazole
miconazole
Term
treats dermatophyte, chiggers, mange, mites
Definition
lime sulfur
Term
treats lesions from yeast
Definition
nystatin
Term
treats mites and sebborhea disorders
Definition
selenium sulfide
Term
treats lesions from mites
Definition
terbenfine
Term
topical retinoid
Definition
tretinoin
Term
uses for retinoids
Definition
acanthosis nigricans
nasal/foot hyperkeratosis
callous pyoderma
chin acne
Term
antiparasitic treats dermatophyte, fleas, ticks
Definition
amitraz
Term
antiparasitic for birds. treats mites,vscabies,
Definition
crotamiton
Term
in flea collars. kills fleas and ticks. repels sandflies. harms fish
Definition
deltamethrin
Term
Frontline ingredient. kills fleas and ticks, mites, chiggers, and mange
Definition
fipronil
Term
insect growth regulators
Definition
(s)-methoprene
pyriproxyfen
Term
kills fleas and ticks, mites. repels mosquito
Definition
permethrins
Term
dewormer, kills demodex, mange
Definition
moxidectin
Term
prevents fleas ticks in cats
Definition
spinetoram
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