Term
|
Definition
| Blocks foregut endoderm from forming liver tissue |
|
|
Term
|
Definition
Promotes formation of ventral structures
Secreted by mesenchyme in lungs to induce branching of lung bud
Required for neural crest cell formation |
|
|
Term
|
Definition
| Transcriptional factor for heart formation |
|
|
Term
|
Definition
| Antagonizes BMP's to form dorsal structures |
|
|
Term
|
Definition
|
|
Term
|
Definition
Contributes to somite formation
Acts as repressor for left sided genes
Induction of mesenchymal/endoderm reaction. Secreted to turn off tips of growing tissue in lung bud so branching occurs
Secreted by floor plate at ventral surface of the neural tube. Responsible for development of neurons and the supporting glia.
Secreted by ZPA at posterior end of limb bud. Its gradient regulates expression along the A/P axis of the limb.
Endoderm of the gut secrete SHH, result in upregulation of factors in the mesoderm, such as the HOX genes in the caudal most portions of the midgut and the hindgut. |
|
|
Term
|
Definition
| Specific genes that express liver formation |
|
|
Term
|
Definition
| Inhibits testes formation |
|
|
Term
|
Definition
Contribute to somite formation
Present for early heart development
Block foregut endoderm from forming liver tissue.
Important for formation of ventral structures.
Secreted at dorsal end of neural tube (roof plate) and is responsible for development of the neurons and the supporting glia.
Secreted by neuroectoderm, combines with Wnt to get induction of neural crest cells.
Activates apoptosis to form digits.
Block inhibitors to allow for the development of the liver. |
|
|
Term
|
Definition
| Transcription factor for right sideness |
|
|
Term
|
Definition
| Promotes formation of ventral structures |
|
|
Term
|
Definition
| Establishes left sideness, induced by nodal |
|
|
Term
|
Definition
| Required for blood islands to create tubes. Causes loosening of cell to cell contacts for angiogenesis to occur. |
|
|
Term
|
Definition
| Induces apical ectodermal ridge (AER) in limb development |
|
|
Term
|
Definition
Induces expression of Nodal on left side and maintains progressive zone in limb development
Down regulates E-cadherin which holds epiblast together so it can form germ layers.
Regulates Brachyury T which promotes mesoderm cell specification |
|
|
Term
|
Definition
| Encodes testes determining factor which causes the production of testosterone |
|
|
Term
|
Definition
| Forms blood islands to form smooth muscle |
|
|
Term
|
Definition
| Marker for neural crest cells |
|
|
Term
|
Definition
Required for generation of blood islands
Block inhibitors to allow liver development |
|
|
Term
|
Definition
| Makes tissue competent to respond to uteric bud. Regulates GDNF and HGF which cause growth of bud. |
|
|
Term
|
Definition
Causes mesenchyme of kidney to be turned into epithelium for nephron formation
Secreted by epidermis to induce expression of FoxD3 by neural crest cells
Inhibited for heart development |
|
|
Term
|
Definition
Responsible for differentiation along the A/P axis.
Responsible for differential development of the brain and spinal cord
Responsible for the differential development of the limb along the A/P and P/D axes.
Responsible for differential development of the caudal portions of the midgut and the hindgut, induced by SHH. |
|
|
Term
|
Definition
| Small block of mesodermal tissue on the posterior end of the limb bud. Induce expression of SHH, whose gradient regulates gene expression along the A/P axis of the limb. |
|
|
Term
|
Definition
| Secreted at dorsal (knuckle) side of limb. Its gradient controls expression along the D/V axis of the limb bud. |
|
|
