Term
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Definition
| One of two genes present at a specific locus |
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Term
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Definition
| T cells whose role is cytokine secretion |
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Term
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Definition
| T cells whose role is cytotoxicity |
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Term
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Definition
Proteins present on ALL nucleated cells -
Antigenic fragments are displayed on the target cell surface within the protein groove |
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Term
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Definition
| The fact that receptors on CD8+ T cells can only recognize antigenic fragments displayed in the groove of Class I MHC protiens |
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Term
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Definition
| Antigen receptors on CD4+ T cells can only recognize antigenic fragments when displayed with Class II MHC on the surface of the antigen presenting cells |
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Term
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Definition
| The antigen receptors on CD4_ T cells can only recognize antigenic fragments displayed in the groove of Class II MHC protiens |
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Term
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Definition
| BOTH alleles are expressed |
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Term
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Definition
| Molecules that are required for activation of some cells |
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Term
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Definition
A vaccuole that is formed
WITHIN THE CYTOSOL |
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Term
| Human Leukocyte Antigens (HLA) |
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Definition
| In humans the MHC protiens may also be referred to as HLA protiens |
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Term
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Definition
A protien that is the same in all cells
Blocks the class II MHC antigen binding site in the ER |
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Term
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Definition
| The occurrence of different forms of particular MHC protiens within a population |
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Term
| professional antigen presenting cell |
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Definition
| Cells whose primary role is to present antigen to T cells |
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Term
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Definition
| A complex of proteolytic enzymes that degrade cytosolic protiens to which UBIQUITIN has been attached |
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Term
| transporter of antigen processing (TAP) |
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Definition
| Proteins to which peptides that have been degrated by the proteosome bind to in order to enter the ER |
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Term
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Definition
| The invariant chain of the Class I MHC cell surface protein |
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