Term
which mediators of inflammation are most likely to cause fever |
|
Definition
|
|
Term
|
Definition
|
|
Term
what are 2 major cytokines best for antiviral |
|
Definition
|
|
Term
what two complements are anaphylaxatoxins |
|
Definition
|
|
Term
what disease has TSH receptor autoantibodies |
|
Definition
|
|
Term
what hypersensitivity causes arthritis, vasculitis, and glomerulonephritis |
|
Definition
|
|
Term
oncogene that causes burkitt lymphoma |
|
Definition
|
|
Term
2 tumor markers for prostate cancer |
|
Definition
|
|
Term
what symbol is female in pedigree |
|
Definition
|
|
Term
on pedigree what does a heterozygote of autosomal recessive look like |
|
Definition
|
|
Term
inheritance of cystic fibrosis |
|
Definition
|
|
Term
inheritance of glucose-6-phosphate DH deficiency |
|
Definition
|
|
Term
inheritance of huntington disease |
|
Definition
|
|
Term
chromosomal deletion of cri du chat |
|
Definition
|
|
Term
HLA type of ankylosing spondylitis |
|
Definition
|
|
Term
most common cancer in men and women |
|
Definition
men: prostate women: breast |
|
|
Term
what is the name of the type of cell one looks for in a test for SLE that involves patient macrophages being mixed with injured leukocytes |
|
Definition
|
|
Term
|
Definition
calcinosis raynauds esophageal dismotility scleroderma telangestica |
|
|
Term
what immune deficiency has tetany and fungal/viral infections |
|
Definition
digeorge: decreased parathyroid leads to decreased Ca and tetany. decreased thymus leads to decreased immune system |
|
|
Term
what do alcohol and barbituates do to p450 |
|
Definition
induce causing more breakdown of drugs |
|
|
Term
to minimize hearing damage aminoglycosides should never be combined with |
|
Definition
|
|
Term
procanamide and hydralazine share common side effect |
|
Definition
lupus like in slow acetylators |
|
|
Term
antidote for opipod overdose |
|
Definition
|
|
Term
when moving a vertebral segment away from neutral, which is passed first: physiologic or anatomic barrier |
|
Definition
|
|
Term
if a patient presents with cool dry ropy right paraspinal area is this a chronic or acute problem |
|
Definition
|
|
Term
if a lumbar vertebraw is neutral and sidebent right which way is it rotated |
|
Definition
|
|
Term
what direction to the superior facets face |
|
Definition
BUM BUL BUM cervical: back, up, medial thracic: back, up, lateral lumbar: back, up, medial |
|
|
Term
sidebending occurs in what plane and axis |
|
Definition
|
|
Term
if a patient complains of upper arm, which anatomic site to you evaluate and treat first |
|
Definition
|
|
Term
is myofascial release direct or indirect |
|
Definition
|
|
Term
what clotting factors are affected by vitamin K |
|
Definition
|
|
Term
3 things that trigger sickling in sickle cell anemia |
|
Definition
low oxygen dehydration acidosis |
|
|
Term
what pneumonia results in cold antibodies |
|
Definition
mycoplasma (anti-RBC Ab cause hemolysis) |
|
|
Term
what deficiency causes megaloblastic anemia and neurologial symptoms |
|
Definition
|
|
Term
what type of cell ruses in number after severe hemorrhage |
|
Definition
|
|
Term
if a patient were infected with parasites what WBC would you expect to see increased in number |
|
Definition
|
|
Term
what leukemia is associated with the philadelphia chromosome |
|
Definition
|
|
Term
what cell type is classic in hodgkins disease |
|
Definition
|
|
Term
what disorder has osteolytic lesions of the skull and pelvis and bence jones proteins in the urine |
|
Definition
|
|
Term
3 features of virchows triad |
|
Definition
blood stasis hypercoaguability endothelial damage (phlebothrombus risk factors/venous clots) |
|
|
Term
what arteritis must be diagnosed early to prevent blindness |
|
Definition
giant cell temporal arteritis |
|
|
Term
what aneurysm is associated with polycystic kidney disease |
|
Definition
|
|
Term
what congenital heart abnormality is characterized by continous machine like murmur |
|
Definition
|
|
Term
what is eisenmenger syndrome |
|
Definition
reverse of a left to right shunt to a right to left shunt leading to pulmonary HTN |
|
|
Term
in ischemic heart disease what two conditions can ST elevation represent |
|
Definition
Q wave MI prinzmetal vasospasm |
|
|
Term
4 major complications of a MI |
|
Definition
cardiogenic shock muscle rupture heart failure arrhythmia |
|
|
Term
are dyspnea and orthopenia a sign of left or right sided heart failure |
|
Definition
|
|
Term
what endocarditis are those with previously damaged or abnormal heart valves are more risk of getting, what is the organism responsible |
|
Definition
subacute - strep viridans (strep of mouth, often mutans), E. coli, gram negatives |
|
|
Term
what syndrome involving the pericardium may occur following a MI |
|
Definition
|
|
Term
|
Definition
rheumatic fever diagnosis
migratory polyarthritis carditis subcutaneous nodules erythema migrinatum syndehams chorea (st. vincent's dance) |
|
|
Term
4 classifications of obstructive lung disease |
|
Definition
chronic bronchitis emphysema asthma broncholyitis |
|
|
Term
what restrictive lung disease is caused by habitual inhalation of irritants like coal dust |
|
Definition
|
|
Term
DOC vaginal candidiasis and systemic candidiasis |
|
Definition
vaginal: miconazole systemic: fluconazole |
|
|
Term
DOC for neisseria meningitidis |
|
Definition
|
|
Term
DOC for neisseria gonorrhea |
|
Definition
|
|
Term
3 anatomical aspects of cervical vertebrae (C2-7) that differ from spinal vertebrae |
|
Definition
transverasarum foramen bifid spines uncovertebral joints of luska |
|
|
Term
what ligament connects the dense to the foramen magnum |
|
Definition
|
|
Term
what scalenes elevate the first rib |
|
Definition
|
|
Term
if you are able to induce left translation what type of sidebending are you inducing |
|
Definition
|
|
Term
if the occiput is rotated right what direction is it sidebent |
|
Definition
|
|
Term
you are about to perform OMT on cervical spine what area must you start |
|
Definition
thoracic spine then start with OA |
|
|
Term
antidote of acetminophen overdose |
|
Definition
|
|
Term
what anti-TB drug is hepatotoxic |
|
Definition
|
|
Term
what drugs are P450 inducers |
|
Definition
"one pharmacetuical brings about rapid liver metabolism" oral contraceptives pnenytoin barbituates ethanol rifampin levodopa methadone |
|
|
Term
2 major causes of lobar pnaumonia |
|
Definition
|
|
Term
4 types of lung carcinoma |
|
Definition
small cell squamous cell large cell adenocarcinoma |
|
|
Term
hematuria and RBC casts are usually indicative what what general classification of glomerulonephritis |
|
Definition
|
|
Term
most common nephrotic syndrome in children |
|
Definition
|
|
Term
three components of staghorn renal calculus, what is the cause |
|
Definition
infection Magnesium, phosphate, ammonia |
|
|
Term
cause and DOC of syphillis |
|
Definition
treponma pallidum penicillin G |
|
|
Term
what testicular germ cell tumor has high AFP, what ovarian tumor is the counterpart |
|
Definition
yolk sac tumor endodermal sinus tumor |
|
|
Term
what ovarian tumor has cysts lined with epithelium |
|
Definition
|
|
Term
5 major risk factors for endometrial carcinoma |
|
Definition
obesity age >40 late menopause early menarche nullparity |
|
|
Term
5 major risk factors for breast cancer |
|
Definition
obesity age >40 early menarche late menopause nullparity |
|
|
Term
koplik spots in mouth indicate what disease |
|
Definition
|
|
Term
what esophageal diverticulum involves all layers of esophagus, which is only mucosal |
|
Definition
all: true mucosa: false/pulsion |
|
|
Term
what do cloxacillin, oxacillin, and methacillin have in common with respect their their ability to kill pathogens |
|
Definition
b lactaminase resistant kill strep and staph |
|
|
Term
what generation of cephalsporins are cefmandole and cefoxitin in |
|
Definition
|
|
Term
what type of gastritis does H. pylori cause, why must it be treated ASAP |
|
Definition
chronic B type can cause gastric carcinoma |
|
|
Term
what is the risk of developing colon cancer in familial polyposis |
|
Definition
|
|
Term
if patient presents with lots of abdominal pain, little to no blood in stool, skip lesions of ileum what is the cause |
|
Definition
|
|
Term
3 components of charcots triad, what abdominal disease does it represent |
|
Definition
RUQ pain, jaundice, fever acute cholangitis |
|
|
Term
where is the cause of jaundice if there is high serum unconjugated bilirubin, high serum conjugated bilirubin, and high serum both |
|
Definition
unconjugated: prehepatic conjugated: post hepatic both: hepatic |
|
|
Term
how are hepatitis A and B transmitted and their incubation times |
|
Definition
A: fecal oral (2-6wk) B: blood, sex, pregnancy (2-6mo) |
|
|
Term
if a patient is positive for anti-HBsAg what disease do they have |
|
Definition
vaccinated for hepatitis B, no disease |
|
|
Term
patient presents with cirrhosis, new onset diabetes, bronze skin, what is the disease |
|
Definition
|
|
Term
compare the finger abnormalities in RA and OA |
|
Definition
RA: PIP and MCP predominate OA: DIP and heperdines nodules |
|
|
Term
rule of three for thoracic vertebrae |
|
Definition
T1-3 spine is at the same level T4-6 spine is 1/2 below T7-9 spine is 1 below T10 spine is 1 below T11 spine is 1/2 below T12 spine is at same level |
|
|
Term
|
Definition
|
|
Term
what is the primary motion of the thoracic spine |
|
Definition
|
|
Term
what are the pump handle, bucket handle, and caliper ribs |
|
Definition
pump: 1-5 bucket: 6-10 caliper: 11-12 |
|
|
Term
what are the attachments of the diaphragm |
|
Definition
ribs 6-12 L1-3 xyphoid process |
|
|
Term
in an inhalation dysfunction is the the key ribs |
|
Definition
|
|
Term
prostaglandins and bradykinins share what common feature in terms of how we feel when we get sick |
|
Definition
|
|
Term
what cell makes IL-1, what does it do |
|
Definition
macrophages make it stimulates CD4 T cell causes fever |
|
|
Term
if there is no male to male transmission and the parents are not sick what is the inheritance |
|
Definition
|
|
Term
what is the HLA type of MS and nacrolepsy |
|
Definition
|
|
Term
what is the VRDL and FTA-ABS test result in a SLE patient, why |
|
Definition
VDRL positive because it tests for anti-cardiolipin (anti-phospholipid Ab) which is on syphillis and also made when SLE destories cells and they body sees the mitochondria membrane
FTA-ABS negative |
|
|
Term
what clotting pathway does PTT, PT, and bleeding time test |
|
Definition
PTT: intrinsic PT: extrinsic bleeding time: platelet number |
|
|
Term
what do the direct and indirect coombs tests evaluate |
|
Definition
direct: anti-Rb antibodies (like in pregnancy) indirect: anti-RBC antibodies (warm/cold hemolytic anemia) |
|
|
Term
what macromolecule is reliant on folic acid and vitamin B12 for synthesis, how is this related to anemia |
|
Definition
DNA if you can't make DNA then cells stop dividing making large cells but less cells |
|
|
Term
auer rods and myeloblasts are evidence of what disease |
|
Definition
|
|
Term
aminoglycosides are most effective against gram positives, gram negatives, or both |
|
Definition
|
|
Term
what type of arterial inflammation is associated with hypersensitivity to tobacco |
|
Definition
buerger's / thromboangiitis obliderans |
|
|
Term
what disease do blue bloaters have, is it obstructive or restrictive |
|
Definition
chronic bronchitis obstructive |
|
|
Term
what drugs are P450 inhibitors |
|
Definition
"some pharmauticals can inhibit drug catabolism" sulfonamides pnehylbutazone chloramphenicol isonizid dicumarol cimetidine |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
what plane and axis is flexion |
|
Definition
plane: horizontal axis: transverse |
|
|
Term
what is the classic cell in hodgkins disease |
|
Definition
|
|
Term
what athlerosclerosis is due to high serum calcium |
|
Definition
|
|
Term
what athlerosclerosis is due to malignant HTN |
|
Definition
hyperplastic arterialLOsclerosis |
|
|
Term
what athlerosclerosis is due to old age |
|
Definition
hayline artheioLOsclerosis |
|
|
Term
what athlerosclerosis is due to high lipid diet |
|
Definition
|
|
Term
a 3yo japanese boy presents with very red hands and soles of the feet, conjunctivitis, what does he have |
|
Definition
|
|
Term
if the atlas is sidebent left what is the rotation |
|
Definition
|
|
Term
if C5 is more easily translated left in flexion and there is equal translation right and left when in neutral and not as equal bilateral translation in extension what is the dysfunction |
|
Definition
C5 neutral rotated right sidebent right |
|
|
Term
is serum calcium, phosphate, and alkaline phosphatase high, normal, or low in oestoperosis, osteomalacia, and pagets |
|
Definition
osteoperosis: normal osteomalacia: low Ca and P, high AP pagets: high AP |
|
|
Term
what is the most common type of cartiladge |
|
Definition
|
|
Term
what bone cancer is agressive, usually in pelvis and long bone marrow cavities, and more in young males |
|
Definition
|
|
Term
why are the calves in duchenne muscular dystrophy large |
|
Definition
infiltration with fat and CT hypertrophy |
|
|
Term
what is the most common supratentorial tumor in children |
|
Definition
|
|
Term
what CNS disorder has bradykinesia, resting tremor, rigidity |
|
Definition
|
|
Term
if one is spastic with increased DTR is it a lower or upper motor neuron lesion |
|
Definition
|
|
Term
what is the age of onset for MS, what is the physiological change |
|
Definition
|
|
Term
what is the hormone produced in cushings syndrome |
|
Definition
|
|
Term
what adrenal products are in excess in Conn's disease, what is the effect on serum Na levels |
|
Definition
|
|
Term
contrast graves disease and plummers hyperthyroid size of follicle and colloid |
|
Definition
graves: small follicle, low colloid plummer: large follicle, high colloid |
|
|
Term
are the PTH and Ca levels high or low in hypoparathyroid and pseudohypoparathyroid |
|
Definition
hypoparathyroid: low PTH and Ca pseydohypoparathyroid: high PTH and low Ca |
|
|
Term
is DM1 or DM2 prone to ketoacidosis and obesity |
|
Definition
DM1 ketoacidosis DM2 obesity |
|
|
Term
what are the 4 organs involved in MEN1 |
|
Definition
pituitary adenoma pancreatic carcinoma parathyroid adrenal adenoma: pheochromocytoma |
|
|
Term
what are the ABC's of melanoma |
|
Definition
A: asymmetry B: irregular borders C: different colors D: diameter >3mm E: different elevations |
|
|
Term
what skin disease is due to autoantibidoes against the intercellular junctions between keratinocytes |
|
Definition
|
|
Term
what are the two organs most affected by mercury poisoning |
|
Definition
|
|
Term
what guanine analog is DOC for herpes simplex |
|
Definition
|
|
Term
what color are gram positive bacteria after gram staining |
|
Definition
|
|
Term
what kind of colitis has a risk after use of broad spectrum antibiotics, what is the causative agent |
|
Definition
clostridium difficile, pseudomembranous
clindamycin |
|
|
Term
what organ is destoried in acetminophen overdose |
|
Definition
|
|
Term
of what are most renal calculi comprised |
|
Definition
|
|
Term
what type of aneurysm are marfans patients most predisposed towards |
|
Definition
|
|
Term
what germ cell tumor is associated with painlss enlargement of the testies and is often curavle because of its radiosensitivity |
|
Definition
|
|
Term
what is the causative agent of condyloma acuminatum and conduloma lata |
|
Definition
acuminatum: HSV lata: syphillis |
|
|
Term
what is the source of a-amanitin |
|
Definition
|
|
Term
if a patient is + HBsAg what is their diagnosis |
|
Definition
|
|
Term
if a patient has rectal pain, bright red blood in stool, pseudopolyps on colonoscopy, what is the disease |
|
Definition
|
|
Term
what kind of tumors other than colon carcinoma are associated with turcots disease |
|
Definition
|
|
Term
what are the 4 subtypes of hodgkins and what type of reed sternburg to they have |
|
Definition
lymphocyte predominate: less RS cells (better prognosis) lymphostocystic RS B markers
nodular sclerosis: lacunar RS, 50/50 RS cells, moderate prognosis
mixed cellularity: classic RS with CD15
lymphocyte depletion class RS, high amounts of RS bad prognosis |
|
|
Term
inheritance of achondroplasia |
|
Definition
|
|
Term
compare and contrast gilbert and crigler najjar |
|
Definition
gilbert: decreased uridine diphosphoglucronlgransferase, mild impairment in uptake, evident in times of stress
crigler: severe impairment of uptake, chronic |
|
|
Term
what cells of CD3a and CD5a stimulate |
|
Definition
mast cells platelets basophils |
|
|
Term
what type of fungal infection is amphotericin used |
|
Definition
disseminated coccidiomycosis rhizopus fusarium alternate for aspergillus, cryptococcal meningitis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
what type of bacterial has no cell wall |
|
Definition
|
|
Term
what is the effect of botulinum toxin on neurons and clinically |
|
Definition
blocks ACh receptors at NMJ 1. constipation 2. flaccid paralysis decending 3. respiratory paralysis |
|
|
Term
what are the O2 requirements for mycobacterium TB |
|
Definition
|
|
Term
2 most common causes of otitis media |
|
Definition
strep pneumo H. influenzae |
|
|
Term
most common cause of pneumonia in young adults |
|
Definition
|
|
Term
3 most common causes of meningitis in neonates |
|
Definition
1. GBS 2. E. coli 3. listeria |
|
|
Term
most common cause of bacterial endocarditis |
|
Definition
|
|
Term
only species of group A B-hemolytic strep |
|
Definition
|
|
Term
S. viridans: hemolytic nature, bile solubility, optochin sensitivity |
|
Definition
alpha hemolytic bile insoluble optochin resistant |
|
|
Term
what organism is associated with waterhouse friderichsen syndrome |
|
Definition
|
|
Term
what is the gram stain of E. coli |
|
Definition
|
|
Term
what two bacteria are arranged in growth pattern like chinese characters |
|
Definition
cornebacterium diptheria listeria monocytogenes |
|
|
Term
two major toxins made by clostridium perfringens and the disease caused by them |
|
Definition
alpha toxin: gas gangrene enterotoxin: food poisoning |
|
|
Term
compare E. coli, salmonella, and shigella in terms of gram stain, motility, and lactose fermentation |
|
Definition
E. coli: gram negative, motile, ferments
Salmonella: gram negative, motile, no ferment
shigella: gram negative, immotile, no ferment |
|
|
Term
|
Definition
|
|
Term
what organism causes pneumonia with cirrent jelly sputum |
|
Definition
|
|
Term
what comma shaped organism causes rice water stool |
|
Definition
|
|
Term
pasteurella is a common pathogen in wounds caused by? what 2 infections does it cause? |
|
Definition
dog/cat bites cellulitis osteomyelitis |
|
|
Term
what organism creates green blue exudate or pus, smells musty, and often infects burns |
|
Definition
|
|
Term
is most illness and morbidity of TB due to the primary or reactivation infection |
|
Definition
|
|
Term
what two bacterial genera where commonly confused with fungi due to the filamentous and branching growth? how are they different in terms of natural habitats and oxygen requirements |
|
Definition
gram positive rods actinomyces: infects contact lenses, water, soil mouth, sinuses nocardia: acid fast, in soil and lungs |
|
|
Term
what is the causative agent of lyme, what is the name of the buch and the lesion |
|
Definition
borella burgdoferi bulls eye rash, erythema chromcum migrans |
|
|
Term
in what form is chalmydia infective |
|
Definition
|
|
Term
what is the most common agent of non-gonoccal urethritis |
|
Definition
|
|
Term
what are the 3 typhi, their cause, and their vector |
|
Definition
epidemic: R. prowazekii, flying squrriel, human, lice
endemic: R. typhi - rats and fleas
scrub: R. tustugamushi - rodents and mites |
|
|
Term
what demyelinating disease follows viral infection, affects PNS, mostly motor, ascending muscle weakness and paralysis |
|
Definition
|
|
Term
what 5 structures must be present for it to be a typical rib |
|
Definition
head neck tubercle angle shaft |
|
|
Term
the spine of the scapula is at what vertebral level |
|
Definition
|
|
Term
route of transmission and incubation time for hepatitis C |
|
Definition
|
|
Term
what is the composition of most kidney stones |
|
Definition
|
|
Term
what two species of bacterial are associated with development of struvite |
|
Definition
proteus morabalis staph saphrophiticus |
|
|
Term
what organs are affected by MEN 1 |
|
Definition
pituitary adenoma adrenal pheochromocytoma parathroid pancreas carcinoma |
|
|
Term
what organs are effected by MEN 2 |
|
Definition
adrenal medulla pheochromocytoma thyroid medullary carcinoma hyperparathyroid |
|
|
Term
describe feet of friedreich's ataxia patients |
|
Definition
pes cavus: cave in sole, high arches |
|
|
Term
is ALS are disease of UMN, LMN, or both |
|
Definition
|
|
Term
what two bones when fractures are notoriously prone to avascular necrosis |
|
Definition
|
|
Term
is there increased conjugated or unconjugated bilirubin in gilberts, crigler najjar, dubin johnson, rotor |
|
Definition
gilbert: UC crigler: UC dubin: C rotor: C |
|
|
Term
what is the difference in terms of formation, components and dangers associated with complete vs incomplete hydatiform mole (used Rehymer explination thought it was better) |
|
Definition
complete: fertilized empty egg with 2 sperm (46 chromosomes). COMPLETE mom absence. COMPLETE villi edematous/hydropic. trophoblasts COMPLETELY cover villi (more b-hCG). COMPLETE risk for choriocarcinoma
partial: fertilize 1 egg with 2 sperm. PARTIAL genetic material correct. PARTIAL fetal formation. PARTIAL circumference of trophoblasts around hydropic villi. villi PARTIALly have edema, some are normal. PARTIAL risk of choriocarcinoma |
|
|
Term
20yo make, bloody stool for 1y, abd pain, symptomatic arthritis, iritis. top of DDX list for the bloody stool is |
|
Definition
|
|
Term
what is the causative agent of 5th disease, what are two other names |
|
Definition
parvovirus B19 slapped cheek disease erythema infectiousum |
|
|
Term
compare chicken pox and small pox synchrony of evolution |
|
Definition
chicken pox are in all different stages small pox are all in the same stage |
|
|
Term
what type of cosackie is associated with myocarditis and what type hand foot and mouth disease |
|
Definition
B is myocarditis A hand foot mouth |
|
|
Term
what causes measles and german measles |
|
Definition
measles is rubeola german measles is rubella |
|
|
Term
what type of disease does rotavirus cause, what family is the virus in |
|
Definition
gastrenteritis in kids reoviridae |
|
|
Term
4 classes of antibiotics that inhibit translation in bacteria |
|
Definition
aminoglycosides macrolides tetracyclines chloramphenicol clindamycin |
|
|
Term
what do methotrexate, trimethoprim, and pyrimethamine have in common |
|
Definition
|
|
Term
what is the MOA of rifampin, what disease does it treat |
|
Definition
transcription inhibitor TB |
|
|
Term
what level does the spinal cord end in most people |
|
Definition
|
|
Term
why is the lumbar spine more susceptible to herniation |
|
Definition
the posterior ligament is thinner |
|
|
Term
what is the primary flexor of the hip |
|
Definition
|
|
Term
how does a small fergusons angle affect the curvature of the spine |
|
Definition
small means they have a flat back with little lordosis |
|
|
Term
if a patient has a herniated L3 disc what root is affected |
|
Definition
|
|
Term
what are the major types of spina bifida and what does each represent |
|
Definition
occulta: laminae malformation, hair or nevi
meningocele: meningies malformation
meinogomyeloele: meninges malformation and herniation of nerve roots
rachischisis: full or open to CNS |
|
|
Term
what is the term for anterior displacement of the vertebrae with respect to the one inferior |
|
Definition
|
|
Term
what dermatone is the umbilicus |
|
Definition
|
|
Term
what is the vector for hanta virus, what infection does it cause |
|
Definition
deer mice urine, feces, saliva respiratory infection |
|
|
Term
what is the causative agent of subacute sclerosing panencephalitis |
|
Definition
|
|
Term
|
Definition
kuru CJV CJV varient bovine encephalitis scarpie fatal familial insomnia gerstmann straussler scheinker |
|
|
Term
what is the term for a virus that integrates itself into the host genome |
|
Definition
|
|
Term
what HIV glycoprotein mediates HIV binding to the CD4 receptor, which mediates HIV fusion to the cell |
|
Definition
|
|
Term
is cryptococcus a yeast or mold |
|
Definition
|
|
Term
if a tissue specimen of infected area reveals cigar shaped budding yeast what is the cause |
|
Definition
|
|
Term
if a slide made from a vaginal swab is examined and germ tubes and pseudohyphae are found what is the infection |
|
Definition
|
|
Term
stages of plasmodia development |
|
Definition
1. sporozoite injected 2. in liver 30min 3. developed into merozoites 4. enter RBC 5. A. make more merozites which lyse RBC every 48h (72h for malariae) 5. B. gametocyte released and sucked into mosquito and turns into sporozoite |
|
|
Term
what species of plasmodium is the most severe and life threatening |
|
Definition
|
|
Term
what is the causative agent of kala-azar, what is another name for this disease |
|
Definition
leshmania donovani black sickness |
|
|
Term
what is the vector and cause of chagas disease |
|
Definition
T. crusi kissing/reduvidd bug |
|
|
Term
DOC for entamoeba histolytica |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
compare location of schistoma mansoni, japonicum, hematobium |
|
Definition
mansoni: colon japonicum: SI and liver hematobium: bladder |
|
|
Term
what is the generic term for cestode |
|
Definition
|
|
Term
what nematode causes perianal puritis especially at night |
|
Definition
pinworm enterobius vermicularis |
|
|
Term
if the Km of an enzyme is high what is the affinity of the substrate |
|
Definition
|
|
Term
by what two amino acids does trypsin cleave, does it cleavy carboxy or amino side |
|
Definition
lysine and argining carboxy |
|
|
Term
what AA is the source of GABA |
|
Definition
|
|
Term
what is the molecular type (macromolecule) of all exotoxins |
|
Definition
polypeptides proteinaceous |
|
|
Term
what PAS character do mucosal macrophages in whipples disease have |
|
Definition
|
|
Term
why is takayasu disease called pulseless disease |
|
Definition
granulomas on aorta decrease recoil and decrease pulse |
|
|
Term
which are motile: E. coli, salmonella, shigella |
|
Definition
|
|
Term
what antibody type crosses the placenta |
|
Definition
|
|
Term
what is the MOA for killing of plasmodium by chloroquine |
|
Definition
makes heme toxic lyses RBC inhibits DNA alkalizes food vacoule |
|
|
Term
|
Definition
kills liver hyponozites kills gametocytes to decrease spread |
|
|
Term
what type of staph is associated with UTI |
|
Definition
|
|
Term
what stain is used for cryptococcus |
|
Definition
|
|
Term
what enzyme does methotrexate inhibit, what effect does this have, what product is no longer made |
|
Definition
inhibits folate which stops dihydrofolate reductase so you cannot turn dihydrofolate into tetrahydrofolate and thus cannot make nucleotides |
|
|
Term
|
Definition
|
|
Term
common contaminating agent of bodies of water with leptospira interrogans |
|
Definition
rat, mouse, cat, dog urine |
|
|
Term
what HLA is associated with psoriatic arthritis, what other disease are associated with this HLA |
|
Definition
B27 ankylosing spondylitis reactive arthritis |
|
|
Term
what is the number one cause for amenorrhea |
|
Definition
|
|
Term
is prader willi due to maternal or paternal deletion of 15q11-13 |
|
Definition
|
|
Term
explain the pentose phosphate shunt |
|
Definition
glucose + Mg + Ca > NADPH + H
NADPH + H + FAD + glutathione reductase > glutathione
glutathione + H20 + glutathione peroxidase > 2 H20 |
|
|
Term
most common side effects of cisplatnin |
|
Definition
peripherial neuropathy ototoxicity nephrotoxicity severe vomiting |
|
|
Term
most common side effects of cyclophosphamide |
|
Definition
hemorrhagic cystitis and fibrosis |
|
|
Term
most common side effects of bleomycin |
|
Definition
pulmonary fibrosis extravasion |
|
|
Term
what enzyme is missing in phenylketonuria |
|
Definition
pnenylalanine hydroxylase |
|
|
Term
|
Definition
dermatitis diarrhea dementia |
|
|
Term
stops from phenylalanine to the production of epinepherine |
|
Definition
pnenylalanine + phenylalanine hydroxylase > tyrosine
tyrosine + tyrosinase > dopa
dopa > dopamine > NE
NE + vitamin C and Ca > epi |
|
|
Term
what amino acids build up in maple suryp urine disease |
|
Definition
isoleucine leucine valine |
|
|
Term
what kind of sugar is glucose based on the number of sugars it has |
|
Definition
|
|
Term
hexokinase vs glucokinase: location and affinity for glucose |
|
Definition
hexokinase: most tissues, low affinity
glucokinase: liver, B islet cells, high affinity |
|
|
Term
what types of glycocidic bonds exist between sugars of sucrose, glycogen and cellulose |
|
Definition
sucrose a1,2 glycogen a1,4, a1,6 cellulose B1,4 |
|
|
Term
lactose intolerance is due to a defect in what enzyme |
|
Definition
|
|
Term
main clinical effects of fructosuria vs fructose intolerance |
|
Definition
fructosuria: benign, fructose in urine
fructose intolerance: fructose builds in kidney and liver causing failure and hypoglycemia |
|
|
Term
why does von girke not invade skeletal muscle |
|
Definition
no gluconeogenesis in muscle |
|
|
Term
what COX inhibitor has no anti-inflammatory activity |
|
Definition
|
|
Term
3 enzymes involved of breaking down glycogen into glucose |
|
Definition
glucose-6-phosphatase phosphorlyase glucomutase |
|
|
Term
what 2 mucopolysaccharidoses have defect in a=L iduronidase |
|
Definition
|
|
Term
are these FA saturated or unsaturated: palmitic, linoleic, linolenic, oleic |
|
Definition
palmitic: saturated lnoleic: poly unsaturated linoleic: poly unsaturated oleic: mono unsaturated |
|
|
Term
what is enterohepatic circulation |
|
Definition
liver > bile > GB > bile ducts > sphinctor of oddi > duodenum > ileum > liver |
|
|
Term
4 components of a triglyceride and glycerophospholipid |
|
Definition
TG: glycerol + 3 FA
glycerophospholipid: glycerol + 2 FA + 1 phospholipid with specific head |
|
|
Term
what type of lipid is lecithin |
|
Definition
|
|
Term
what type of lipid is cardiolipin |
|
Definition
|
|
Term
what sphingolipidosis is associated with blindness and a cherry red macula and is more common in jews |
|
Definition
|
|
Term
what enzyme is defective in gauchers |
|
Definition
|
|
Term
what is the mechanism of photosensitivty associated with prophyrias |
|
Definition
sun turns prophinogen into porphoryn oxygen causes porphoryn to release ROS ROS causes photosensitivty reaction |
|
|
Term
what steps of heme synthesis does lead inhibit |
|
Definition
ALA dehydrogenase ferrocheltilase |
|
|
Term
what 2 metabolic processes does the liver use to maintain glucose levels |
|
Definition
glycogenolysis gluconeogenesis |
|
|
Term
in normal non fasting person what is the only energy sources for the brain and for RBC, what about in starvation |
|
Definition
non fasting: both use glucose
starvation: brain can use ketones, RBC need glucose |
|
|
Term
what is the disorder caused by thiamine deficiency |
|
Definition
|
|
Term
what virus causes measles |
|
Definition
|
|
Term
which cosackie virus causes myocarditis |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
doxycycline or ceftriadone |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
what ribosome subunit is acted on by aminoglycocides |
|
Definition
|
|
Term
what ribosome subunit is acted on by tetracyclines |
|
Definition
|
|
Term
what ribosome subunit is acted on by chlorphenicol |
|
Definition
|
|
Term
what ribosome subunit is acted on my macrolides |
|
Definition
|
|
Term
in what developmental stage are plasmodia when they are injected into human body |
|
Definition
|
|
Term
what is the cause of infectious mononucleosis |
|
Definition
|
|
Term
|
Definition
stops macrophage lysosome formation builds up in joints best |
|
|
Term
|
Definition
first line is NSAID DOC colchisine |
|
|
Term
how many vertebrae is the sacrum |
|
Definition
|
|
Term
3 accessory ligaments of the sacrum and their attachment |
|
Definition
sacrotuberosus: sacrum, ischial tuberosiry
sacrospinous: sacrum, ischial spine
iliolumbar: iliac crest, L5-5 |
|
|
Term
what is the first ligament to become tender in a lumbosacral dysfunction |
|
Definition
|
|
Term
3 functions of the piriformis |
|
Definition
external rotation abduction extension |
|
|
Term
what nerve roots constribute to the lumbar plexus, sacral plexus, and sciatic nerve |
|
Definition
lumbar: T12-L4 sacral: L2-S4 sciatic: L2-S3 |
|
|
Term
4 types of sacral motion, under what conditions, what horizontal axis |
|
Definition
inherent (S2): craniosacral, superior axis respiratory: horizontal postural: transverse S3 dynamic: oblique |
|
|
Term
if L5 is rotated left what direction is the sacrum rotated |
|
Definition
|
|
Term
if L5 is sidebent left what side is an oblique axis of the sacrum engaged |
|
Definition
|
|
Term
what enzyme in the glycolytic pathway is inhibited by ATP and citrate but activated by AMP and 2,6-diphosphate |
|
Definition
|
|
Term
what effect does phosphorlyation have on hormone sensitive lipase |
|
Definition
|
|
Term
what class of steroid are glycocholate, taurocholate, cortisol, DHEAS |
|
Definition
glycholate: bile acids cortisol: glucocorticoids: DHEAS androgen |
|
|
Term
what layer of the adrenal cortex produces aldosterone, cortisol, and testosterone |
|
Definition
zona glomerulosa: ALD zona fasicularis: cortisol zona reticularis: testosterone |
|
|
Term
do the testies make glucocorticoids and ALD |
|
Definition
|
|
Term
in male peripheral metabolism and two molecules is testosterone converted to |
|
Definition
|
|
Term
what cells of the ovary have the same chlesterole dependent pathway as the same productions of that pathway as leydig cells of the testes |
|
Definition
theca cells produce androgen |
|
|
Term
in the granulosa cells of the ovary what two molecules is androstendione converted to |
|
Definition
|
|
Term
how does female peripheral metabolism differ from male peripheral metabolism with regard to cholesterol dependent products |
|
Definition
male: DHT > androsteindione, estrone, testosterone
female; estrol > androstendione, estrone, testosterone |
|
|
Term
does the corpus luteum make esteogrn |
|
Definition
|
|
Term
in 17a-hydroxylase deficiency what hormones are deficient |
|
Definition
|
|
Term
in 21a-hydroxylase deficiency what hormones are deficient |
|
Definition
|
|
Term
in 11b-hydroxylase deficiency what hormones are deficient |
|
Definition
|
|
Term
is fat lysis stimulated by insulin, glucogen, or growth hormone |
|
Definition
glycogen and growth hormone |
|
|
Term
what are the purines and pyrimidines |
|
Definition
purines: adenosine, guanine pyrimidines: uracil, thymidine, cytosine |
|
|
Term
in lesch nyhan defective HGPT causes inability to salvage purines so they are degraded to this molecule which is the cause of the symptoms |
|
Definition
|
|
Term
the segment of bacterial DNA that consists of promoter, operator, and one or more structural genes is called |
|
Definition
|
|
Term
how many structural genes are associated with promoter in prolaryotic genome and eukaryotic genome |
|
Definition
monocystrionic in eukaryotes
polycystronic in prokaryotes |
|
|
Term
if one has a seated flexion test positive on the left and there is a sacral oblique axis on what side will it be |
|
Definition
|
|
Term
what does the standing flexion test evaluate that the seated flexion does not |
|
Definition
|
|
Term
if the right ASIS is inferior and the right PSIS is superior and there is a positive standing flexion test on the right what is the innominate dysfunction |
|
Definition
|
|
Term
if the right ASIS is super and the right PSIS is superior and there is a positive standing flexion on the right, what is the inomniate dysfunction |
|
Definition
|
|
Term
4 causes of superior pubic shear |
|
Definition
tight rectus abdomnius pregnancy/labor trauma posterior innominate |
|
|
Term
if the right ASIS is more lateral and there is a positive standing flexion test on the right what is the likley innominate dysfunction |
|
Definition
|
|
Term
what sacral dysfunction is VERY common in post partum females |
|
Definition
|
|
Term
what is the most common sacral shear |
|
Definition
|
|
Term
the pt has left on left, what type of sacral dysfunction is this |
|
Definition
physiological, forward torsion |
|
|
Term
if there is a sacral dysfunction what area should be evaluated and treated first |
|
Definition
|
|
Term
what is the class of drug for cantopril and enalapril |
|
Definition
|
|
Term
what changes occur in electrolytes, urea, and glucose with thiazides |
|
Definition
decreased Na and K increased Ca and uric acid hypoglycemia |
|
|
Term
what region of DNA encodes a single protein in prokaryotes |
|
Definition
|
|
Term
what is the major DNA polymerae in prokaryotes, what are its functions |
|
Definition
RNA polymerase III: proofread, exonuclease, catalyze DNA replication |
|
|
Term
what type of polymerase makes the leading strand in eukaryotic DNA replication, what are its other functions |
|
Definition
polymerase E: acts as helicase (UNABLE to proofread or do exonuclease) |
|
|
Term
what are the 3 germ layers |
|
Definition
|
|
Term
the median and medial umbilical ligaments were what structure in the fetus |
|
Definition
median: urachius mediaL: umbiLicaL artery |
|
|
Term
what branch of the branchial arch are the muscles of mastication and facial expression derived |
|
Definition
1st mastication 2nd facial expression |
|
|
Term
from what pharyngeal pouches are the thymus and inferior parathyroids derived |
|
Definition
|
|
Term
where are the cervical cysts located, from what fetal structure do they derive |
|
Definition
anterior lateral neck remnent of pharyngeal cleft |
|
|
Term
what duct evuntally develops into vas deferens and epididymis |
|
Definition
|
|
Term
what duct evuntally develops into fallopian tubes? |
|
Definition
|
|
Term
what structures pass through the foramen ovale |
|
Definition
V3 accessory meningeal artery |
|
|
Term
what structures pass through the foramen spongiosum |
|
Definition
|
|
Term
what structures pass through the superior orbital fissure |
|
Definition
CN 3, 4, 6, superior opthalmic vein sympathetic nerves |
|
|
Term
what is the innervation of the lateral rectus |
|
Definition
|
|
Term
what is the innervation of the superior oblique |
|
Definition
|
|
Term
what muscle is relaxed in horner syndrome, why |
|
Definition
muellers muscle disrupted sympathetic control |
|
|
Term
what muscle is responsible for midrasis and miosis |
|
Definition
sphinctor pupiale - miosis dilator pupiale - mydriasis |
|
|
Term
pt has injury to right 12th CN to what side will that patients tongue deviate when he attempts to protrude his tongue |
|
Definition
|
|
Term
which pterygoid operates to open the mouth |
|
Definition
|
|
Term
what laryngeal muscle is NOT innervated by the recurrent laryngeal, what is the innervation |
|
Definition
crycopharyngeal - superior laryngeal |
|
|
Term
what muscle is paralized in scapular winging, what nerve |
|
Definition
serratus anterior long thoracic nerve |
|
|
Term
what nerve roots supply the musculocutaneous, axillary, radial, and ulnar nerve |
|
Definition
MCT: C5-6 axillary: C7 radial: C7 ulnar: C8-T1 |
|
|
Term
what cutaneous loss is associated with unlar nerve, musculocutaneous nerve, and radial nerve damage |
|
Definition
ulnar: fingers 4.5-5 and lateral hand MCT: lateral forearm radial: lateral posterior forearm and hand without tips |
|
|
Term
what nerve risks injury with a fracture to the humerus |
|
Definition
|
|
Term
what type of fracture is a fracture of the distal radius |
|
Definition
collies: land on outstretched hand |
|
|
Term
for the hip what is the primary abduction, adductor, internal rotator, external rotator |
|
Definition
abd: gluteus medius add: adductor magnus and minimus external: gluteus maximus internal: gluteus medius and minimus |
|
|
Term
what type of glomerular disease has crescents |
|
Definition
rapid proliferative glomerular nephritis |
|
|
Term
what are the categories of RPGN |
|
Definition
1) Ab- idiopathic, goodpastures
2) immune complex- idiopathic, SLE, henoch purpura, post strep
3) ANCA- idiopathic, wegeners, micropolyangitis, polyarteritis nodosa |
|
|
Term
what type of glomerulonephritis is goodpastures disease |
|
Definition
nephritis anti-glomerular BM disease rapid proliferative later |
|
|
Term
if a pt presents with inhaled dysfunction of ribs 3, 4, 5 what rib should you treat first |
|
Definition
|
|
Term
what is the main motion of the OA, AA, and upper cervicals |
|
Definition
OA: F/E AA: rotation cervicals: rotation |
|
|
Term
|
Definition
|
|
Term
DOC esophageal candidiasis |
|
Definition
|
|
Term
what generation of cephalosporin is cefazolin, cefoxitin, and ceftriaxone |
|
Definition
cefazolin 3 cefoxitin 2 ceftriaxone 3 |
|
|
Term
what is the antidote to warfarin OD |
|
Definition
|
|
Term
what is the antidote to benzo OD |
|
Definition
|
|
Term
what drug is used to eliminate tapeworms |
|
Definition
|
|
Term
what drug is used to eliminate flukes |
|
Definition
|
|
Term
What is the innervation of the hamstrings |
|
Definition
|
|
Term
what is the innervation of the quadriceps |
|
Definition
|
|
Term
what are the muscles of the hamstrings |
|
Definition
biceps femoris semitendinosus semimembranosis |
|
|
Term
how is foot movement affected by a peroneal nerve injury |
|
Definition
|
|
Term
contents of superior, middle, posterior, and anterior mediastinum |
|
Definition
superior: thymus, aortic arch, esophagus, trachea
anterior: nothing
middle: heart
posterior: esophagus |
|
|
Term
at what point in the cycle of heart contraction and relaxation is the blood flow through the coronary arteries the greatest |
|
Definition
|
|
Term
what three arterial trunks come from aorta and feed abdominal viscera |
|
Definition
celiac: stomach superior mesenteric: transverse colon, SI inferior mesenteric: sigmoid colon |
|
|
Term
three shunts caused by portal HTN |
|
Definition
esophageal varices hemorrhoids caput medusa |
|
|
Term
where is McBurney's point |
|
Definition
|
|
Term
what is the triad for peridonitits |
|
Definition
rebound tenderness rigidity of muscles abdominal pain |
|
|
Term
what are the layers of spermatic cord superificial to deep |
|
Definition
skin superificial fascia cremasteric muscle peritoneum (internal spermatic fascia) tunica vaginalis (loose CT) testies |
|
|
Term
where does the ovarian artery originate |
|
Definition
|
|
Term
compare brocas aphasia with wernickes aphasua |
|
Definition
wernickes: cannot understand but can speek fluently
brocas: can understand but cannot speak |
|
|
Term
what artery supplies the lateral cortex |
|
Definition
|
|
Term
what artery supplies the medial cortex |
|
Definition
|
|
Term
5 signs associated with transient ischemia involving vertebrobasilar artery insufficiency |
|
Definition
ataxia nausea facial muscle weakness vertigo diplopia |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
what CN do facial expression |
|
Definition
|
|
Term
what CN do sensory for viscera |
|
Definition
|
|
Term
what CN connects to Ed West nuclei |
|
Definition
|
|
Term
what CN connect to inferior salivary nuclei |
|
Definition
|
|
Term
what CN connect to dorsal motor nuclei |
|
Definition
|
|
Term
what part of striatum atrophies in huntington disease |
|
Definition
caudate, putamen, frontal cortex |
|
|
Term
what part of the brainstem is lost in parkinsons disease |
|
Definition
substantia nigra and locus cerilleus |
|
|
Term
what part of basal ganglion (and its two structures) is site of copper accumulation in wilsons disease |
|
Definition
centicular nuclei: putamen and globus pallidus |
|
|
Term
that thalamus recieves all sensory input except for one |
|
Definition
|
|
Term
what part of the brainstem is destoried in wallenburg syndrome, what artery causes it |
|
Definition
lateral medulla posterior superior cerebellar artery |
|
|
Term
if contralateral body pain and temperature sensation is lost what tract has been injured |
|
Definition
|
|
Term
what occurs if the cortocospinal tract is damaged |
|
Definition
UMN damage: decreased motor, spastic paralysis contralateral hemiparesis of trunk and limbs |
|
|
Term
what lesion tops the ddx if there is muscle weakness and loss of sensation in the right arm |
|
Definition
|
|
Term
what lesion tops the ddx if there is muscle weakness and loss of sensation in the left leg |
|
Definition
right anterior cerebral artery |
|
|
Term
in what dermatome is the anus, umbilicus, bit toe |
|
Definition
anus: S5 umbilucus: T10 Toe: L5 |
|
|
Term
if L5 transverse process articulates or is fused with the sacrum what is the disorder |
|
Definition
|
|
Term
what gene makes gp41, gp120, p24, reverse transcriptase in HIV |
|
Definition
gag: p24 (capsid) pol: reverse transcriptase env: gp160 > gp120 (binds CD4) + gp21 (binds CCR5) |
|
|
Term
what comma shaped organism is renowned for causing ricewater stool and transmitted in contaminated water |
|
Definition
|
|
Term
what is the duration of pain for a MI |
|
Definition
|
|
Term
why is thromboxane a pro-coagulant |
|
Definition
used by platelets to stick together |
|
|
Term
what nerve root is tested by biceps reflex |
|
Definition
|
|
Term
if you wanted to test ROM of shoulder what would be the best |
|
Definition
|
|
Term
what is the most common cause of brachial plexus injury, what nerve roots is it |
|
Definition
|
|
Term
what tests are positive in thoracic outlet syndrome |
|
Definition
apleys scratch test roo test absens (the arm to the side and loose pulse thingy) |
|
|
Term
how does adhesive capsulitis develop |
|
Definition
injury and immobilization allows for adhesions to form in healing |
|
|
Term
what is the normal carrying angle of the female arm |
|
Definition
|
|
Term
what are two primary supinators of the forearm |
|
Definition
|
|
Term
what is the technical term for tennis elbow and strain of what group of muscles (flexors or extensors) caused it |
|
Definition
lateral epicondylitis extensors |
|
|
Term
three tests for carpal tunnel |
|
Definition
|
|
Term
what nerve is entraped in carpal tunnel |
|
Definition
|
|
Term
if the MCP and DIP are extended, and the PIP is constracted, what is the hand deformity |
|
Definition
|
|
Term
what nerves are damaged in bishops deformity |
|
Definition
unlar: if the pinky and ring cannot be lifted median: if the pointer and middle are stuck up and the pt cant bend them down |
|
|
Term
what is the main difference in the mechanism of action between straptoinase and TPA |
|
Definition
TPA only lyses thrombin that is already bound(causes less unintended bleeding) streptokinase lyses all thrombin |
|
|
Term
what is the general mechanism of the 4 classes of anti arrhythmic drugs |
|
Definition
1) decreases Na 2) BB 3) decreases K 4) CCB |
|
|
Term
what two classes of inotropic agents do digoxin and digitoxin belong |
|
Definition
|
|
Term
what is the formula for calculating mean blood pressure |
|
Definition
systole - 1/3(systole-diastole) |
|
|
Term
what is the formula for calculating CO |
|
Definition
|
|
Term
what is the formula for calculating TPR |
|
Definition
|
|
Term
what is the formula for calculating renal clearance |
|
Definition
C = (solute in urine x volume in urine) / solute in plasme
AKA C = (pee x pee) / blood |
|
|
Term
which regulates bicarbonate and which regulates CO2, kidney or lung |
|
Definition
lung CO2 kidney bicarbonate |
|
|
Term
what is the formula for elasticity |
|
Definition
E = 1 / compliance
E = change in pressure / change in volume |
|
|
Term
what is the formula for compliance |
|
Definition
C = change in volume / change in pressure |
|
|
Term
what ion channel is open in upstroke of action potential |
|
Definition
|
|
Term
is the Na/K channel active, facillitated, or secondary active transport. what about Na/glucose |
|
Definition
Na/K - active Na/glucose - facillitated |
|
|
Term
what is the major PROPHYLACTIC agent for asthma |
|
Definition
|
|
Term
what 2 receptor types if stimulated result in cAMP increase |
|
Definition
|
|
Term
what 3 hormones or drugs increase cGMP |
|
Definition
|
|
Term
with G proteins which one inhibits adenylate cyclase, which stimulates it, which activates phospholipase C |
|
Definition
Gi inhibits Gs stimulates Gq phospholipase C |
|
|
Term
what type of nerve fiber innervates skeletal muscles |
|
Definition
|
|
Term
what is the diameter of a skeletal muscle fiber in comparison with others |
|
Definition
large, myelinated, fast A-alpha fiber |
|
|
Term
what two types of nerve fibers are involved with afferent and efferent innervation of muscle spindles |
|
Definition
afferent: alpha 1 and 2 efferent: gamma |
|
|
Term
what touch receptors sense pressure, touch, pain/temp, vibration |
|
Definition
pressure: merkel touch: meissners, follicle sensors vibration: pancinian temp: free nerve endings pain: free nerve endings |
|
|
Term
describe the elasticity in presbyopic patients |
|
Definition
decreased elasticity due to aging (need reading glasses) |
|
|
Term
does the slow or fast phase of eye movement determine direction of nystagmus |
|
Definition
|
|
Term
what are the results of the rinne and webber in conduction deafness |
|
Definition
webber: lateralize to the bar ear bc not distracted by other sounds rinne: BC > AC |
|
|
Term
what does sympathetic stimulation do to bronchi, GI sphincters, pupils, GI motility |
|
Definition
bronchi: dilate sphincter: contract pupil: mydriasis (contract iris dilator) motility: decrease |
|
|
Term
which cholinergic receptors are on sweat glands |
|
Definition
|
|
Term
which adrenergic receptor causes bronchidilation, presynaptic sympathetic inhibition, sympatheitc stimulation in heart, vasoconstriction in the GI tract |
|
Definition
bronchodilation B2 presynapse inhibition A2 sympathetic heart B1 vasocon Gi A1 |
|
|
Term
what is the parasympathetic stimulation of the SA/AV in the heart, what does it cause to happen |
|
Definition
left vagus: AV node decreased conduction and atrium contraction
right vagus: SA node decrease frequency |
|
|
Term
what component of muscle measures the muscle length |
|
Definition
|
|
Term
when the muscle spindle is activated what does it do to the muscle |
|
Definition
activate it (causes pain and tightness) |
|
|
Term
which has higher glycolytic capacity red or white skeletal muscle |
|
Definition
|
|
Term
what does Ca bind to in activating skeletal muscle, smooth muscle, and heart muscle |
|
Definition
skeletal: traponin C smooth: calmodulin heart: traponin C |
|
|
Term
what does the a wave represent in assessing cardiac pressure |
|
Definition
|
|
Term
in what part of the lung is perfusion the greatest, where is ventilation the greatest |
|
Definition
base (area 3): perfusion > ventilation apex (area 1): ventilation > perfusion |
|
|
Term
what level of te brainstem may a transection occur that will have no effect on respiration |
|
Definition
|
|
Term
what adrenal disorder has overproduction of androgens |
|
Definition
11 and 21 enzyme thingy deficiency (virilization) |
|
|
Term
what adrenal disorder has overproduction of mineral corticoids |
|
Definition
17 enzyme thingy deficiency (conns) |
|
|
Term
what adrenal disorder has over production of glucacorticoids |
|
Definition
21 enzyme thingy deficiency (cushings) |
|
|
Term
what is the primary motion of T11 and T12 |
|
Definition
flexion and extension (the rest of the thoracic is rotation!!) |
|
|
Term
what rib dysfunction has the ribs stuck down, what is the restriction, what is the key rib |
|
Definition
dysfunction: inhaled restriction: exhaled key: bottom rib |
|
|
Term
what gender is dysplastic spondylolisthesis most common, what type of spondylolisthesis is it, when does the initial deficit occur |
|
Definition
F>M type 1 congenital, birth it is present symptomatic 7-9yo |
|
|
Term
what is the first line drug for newly diagnosed DM2 |
|
Definition
|
|
Term
what defect results in each hyperlipidemia: 1, 2a, 2b, |
|
Definition
1) LPL deficiency 2a) LDL receptor defect 2b) b100 defect 3) apo E deficiency 4) VLDL and underutilization |
|
|
Term
how many kcal/g of energy is made by the metabolism of carbs, fat, proteins |
|
Definition
|
|
Term
what is the primary disturbance causing respiratory acidosis and metabolic acidosis |
|
Definition
respiratory CO2 metabolic decreased bicarb |
|
|
Term
what are the two normal Hb in an adult |
|
Definition
HbA (a2, B2) HbA2 (a2, gamma2) |
|
|
Term
what Hb is elevated in hyperglycemia |
|
Definition
|
|
Term
4 situations that reduce O2 binding to Hb |
|
Definition
acidic CO increased temp 1,3-DPG |
|
|
Term
what are the two primary functions of albumin |
|
Definition
carry lipid soluble things in the blood create oncotic pressure to draw water in |
|
|
Term
which part of the circulatory system holds the largest volume of blood, which has the greatest cross sectional area, which has the most resistance |
|
Definition
largest: veins area: capillaries resistance: arteriOLES |
|
|
Term
what two vessels does the ductus arteriosus connect, if patent what body part recieves full oxygendation despite PDA |
|
Definition
pulmonary artery and aorta
head and upper extremities because the PDA comes after the first branches off the aorta |
|
|
Term
at what part of the renal tubule do carbonic anhydrase inhibitors function, loop diuretics, and thiazides |
|
Definition
CA: PCT loop: thick descending limp of henle thiazide: DCT |
|
|
Term
what part of kindy resorbs glucose and AA, which secretes K |
|
Definition
resorbs: PCT secretes: collecting duct |
|
|
Term
what is the normal value of GFR |
|
Definition
|
|
Term
is the ICF increased decrease or unchanged in hypotonic dehydration, hypotonic hydration, isotonic dehydration |
|
Definition
hypotonic dehydration: increased hypotonic hydration: decreased isotonic dehydration: no change |
|
|
Term
in what part of kidney is the macular densa, what does it sense |
|
Definition
DCT, Na concentration decreases |
|
|
Term
what is the renin level in Bartter's syndrome, what is the BP |
|
Definition
|
|
Term
what metabolic process does niacin prevent in adipocytes, what is the primary adverse drug reaction |
|
Definition
stops lipoprotein lipase flushing, puritis |
|
|
Term
what enzyme is inhibited by statins |
|
Definition
|
|
Term
cimetidine and ranitidine block what receptor |
|
Definition
|
|
Term
what molecule transports Fe |
|
Definition
|
|
Term
|
Definition
|
|
Term
what are the main products of mucous cells, parietal cells, and chief cells |
|
Definition
mucous: bicarbonate, mucous chief cells: pepsinogen parietal cells: HCl, intrinsic factor |
|
|
Term
what is the direct result of secretin release |
|
Definition
stomach motility bicarb pancreas secretion |
|
|
Term
what is the direct result of CCK release |
|
Definition
pancreatic exocrine secretion gallbladder contraction |
|
|
Term
what disease is defined by hyperaldosteronism |
|
Definition
ALD producing adenoma (Conn's syndrome) |
|
|
Term
effects insulin has on liver metabolism |
|
Definition
increases glyconeogenesis decreases gluconeogenesis decreases glycogenolysis decreases FA oxidation increases lipogenesis |
|
|
Term
what age does separation anxiety occur |
|
Definition
|
|
Term
what age does a baby sit alone |
|
Definition
|
|
Term
what age does a baby stand holding onto nearby objects |
|
Definition
|
|
Term
what age does a baby stand alone |
|
Definition
|
|
Term
what ages does a baby walk alone |
|
Definition
|
|
Term
|
Definition
|
|
Term
what are the IQ ranges for mild MR, moderate MR, severe MR, and profound MR |
|
Definition
mild: 55-79 mod: 40-55 severe: 25-40 profound: <25 |
|
|
Term
define operant conditioning |
|
Definition
permanent effects punishment for behavior |
|
|
Term
define classical condtioning |
|
Definition
effects do not last rewarded for good behavior works better on reflexive behavior |
|
|
Term
what do nodules (micro/macronodular) indicate about the liver |
|
Definition
had liver injury and regeneration |
|
|
Term
what vertebral level is the sternal notch |
|
Definition
|
|
Term
at what vertebral level is the sternal angle |
|
Definition
|
|
Term
what is the main motion in assessing the OA |
|
Definition
|
|
Term
what type of hypersensitivity has uticaria, erythema, bronchiole constriction |
|
Definition
|
|
Term
what AB is associated with RA, SLE, celiac, and wegeners |
|
Definition
RA: anti-IgG aka RF SLE: anti-dsDNA, anti-smith celiac: anti-glidan wegeners: c-ANCA |
|
|
Term
what type of cell is stimulated by IL4 and IL5 |
|
Definition
|
|
Term
what effect does NO have on the vessels |
|
Definition
|
|
Term
what is the moa dipyridamole, why is it used |
|
Definition
decreases PDE which decreases TXA2 which decreases platelet ADHESION
with warfarin: decreases clots in replacement valves
with aspirin: chronic platelet adhesion prevention
radiotracers: stress tests |
|
|
Term
what is the MOA doxorubicin, what is the classic side effect |
|
Definition
decreases topoisomerase II which makes Fe ROS by decreasing IP3
cardiotixicity, red urine |
|
|
Term
what disease is endemic to south west US and is arked by fever, cough, arthralgia |
|
Definition
coccidioidomycosis / valley fever |
|
|
Term
what disorder has personality changes, intelluctual deterioration, autonomic motor dysfunctions, and occurs as a result of HIV infection |
|
Definition
|
|
Term
what are the 3 antibiotics most common to cause pseudomembranous collitis |
|
Definition
clindamycin cephalosporin ampicillin |
|
|
Term
largest joint in the body |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
ligament of the knee that connects to the ant tibia and post femur |
|
Definition
|
|
Term
ligament of the knee that connects to the post tibia and the ant femur |
|
Definition
|
|
Term
ligament of the knee that prevents knee hyperextension |
|
Definition
|
|
Term
what does a positive anterior drawer test indicate |
|
Definition
|
|
Term
test for a meniscus injury |
|
Definition
apleys compression mcmucrrys |
|
|
Term
2 divisions of the sciatic nerve |
|
Definition
tibia and femoral (peroneal) |
|
|
Term
what nerve roots make the femoral nerve |
|
Definition
|
|
Term
a patient complains of superificial knee pain on medial aspect of the leg half way between the ankle and the knee, what dermatome is it |
|
Definition
|
|
Term
what dermatome is the big toe |
|
Definition
|
|
Term
achilles reflex is what nerve root |
|
Definition
|
|
Term
patellar reflex is what nerve root |
|
Definition
|
|
Term
what degree of angulatioon for the femoral head is normal |
|
Definition
|
|
Term
what degree of angulation for the Q angle is normal |
|
Definition
|
|
Term
what are the three positions of pronation |
|
Definition
dorsiflex external rotation abduction |
|
|
Term
a pt presets with supinated right foot what can be said about the fibular head |
|
Definition
|
|
Term
what nerve can be damaged by a posterior fibular head |
|
Definition
|
|
Term
what is the most common compartment syndrome |
|
Definition
|
|
Term
pt presents with ankle sprain, there is trace laxity, only involves that anterior talofibular ligament, what is the degree and type of sprain |
|
Definition
|
|
Term
what are the components of odonahues triad |
|
Definition
medial meniscus medial collateral ACL |
|
|
Term
which position of the ankle is most stable |
|
Definition
|
|
Term
which set of ligaments are the most common involved in ankle sprains |
|
Definition
|
|
Term
what kind of blocker is prazosin |
|
Definition
|
|
Term
|
Definition
|
|
Term
what receptors do dobutamine, dopamine, and isoproterenol stimulate |
|
Definition
dobutamine B1 dopamine D1 B1 isoproterenol B1 B2 |
|
|
Term
|
Definition
|
|
Term
what cholenesterase inhibitor is used to test for myasthenia gravis |
|
Definition
|
|
Term
|
Definition
irreversible acetylcholinesterase inhibitors |
|
|
Term
what is the difference between denial and repression |
|
Definition
denial: pretending like it didnt happen even though you know it did
repression: auctally not remembering it happened, supression of emotion and memory |
|
|
Term
when does REM begin when a nacroleptic falls into a narcoleptic state |
|
Definition
|
|
Term
what is the difference between central and obstrictuve sleep apnea |
|
Definition
central: medulla chemoreceptors are not sensing or not working
obstructive: physical block |
|
|
Term
list the 5 stages of dying |
|
Definition
denial anger barganing depression acceptance |
|
|
Term
what neurotransmitters are high or low in schizophrenia, depression, alzheimers, anxiety |
|
Definition
schizophrenia high DA depression low SE/DA/NE alzheimers low DA high ACh anziety low GABA |
|
|
Term
compare conciousness, speed on onset and reversibaility of delirium and dementia |
|
Definition
delirium: acute, reversible, some conciousness
dementia: chronic, irreversible, concious |
|
|
Term
personality type where someone feels better than others all the type |
|
Definition
|
|
Term
personality type with dramatic emotion personality that may have some level of sexual promiscuity |
|
Definition
|
|
Term
what category of disorders are phobias, agoraphobia, PTSD in |
|
Definition
|
|
Term
how does the duration of symptoms compare between somatization and conversion disorder |
|
Definition
somatization lasts years conversion lasts days to weeks |
|
|
Term
if a schizophrenic presents with hallucinations and delusions what type of symptoms are these classified as under heading of schizophrenia |
|
Definition
|
|
Term
at what point in the night does a person with major depression have the most difficulty remaining asleep |
|
Definition
|
|
Term
what type of epilepsy is marked by 3sec spike and domes on EEG during attack |
|
Definition
|
|
Term
what are the two major signs of opioid intoxication |
|
Definition
|
|
Term
what are 4 major signs of opioid withdrawal |
|
Definition
nausea/vomiting sweating fever muscle aches |
|
|
Term
4 risk factors for physical child abuse |
|
Definition
parent hx of abuse as child poverty premature or low birth weight parent drug abuse |
|
|
Term
2 risk factors for sexual child abuse |
|
Definition
single parent home parent does drugs |
|
|
Term
what percent is included in +/-1, +/-2, +/23 standard deviation |
|
Definition
|
|
Term
probability that a negative test result is actually negative |
|
Definition
negative perdective value |
|
|
Term
probability that a positive test result is actually positive |
|
Definition
positive perdictive value |
|
|
Term
probability an ill patient will have a positive test |
|
Definition
|
|
Term
probablity a healthy patient with have a negative test |
|
Definition
|
|
Term
what is the term for the number of people who have a specific disease at a given point in time per 100,000 people |
|
Definition
|
|
Term
what is the term for the number of new people that develop a specific disease in a year per 100,000 peple |
|
Definition
|
|
Term
in a randomized clinical trial what type of error results in rejection of the null hypothesis even though the null hypothesis is true |
|
Definition
|
|
Term
in observed cohort what is the term for ability of a test to test what is ment to test |
|
Definition
|
|
Term
what is the term for how well the test results can be reproduced |
|
Definition
|
|
Term
what two components are needed for someone to be involuntairly treated |
|
Definition
mentally ill AND in danger of self or others |
|
|
Term
what 4 situations are parental consent not needed in treatment of a minor |
|
Definition
emergency pregnancy STF judge determined |
|
|
Term
what government insurance is for the poor |
|
Definition
|
|
Term
what government insurance is for the elderly |
|
Definition
|
|
Term
what type of bladder is created by spinal cord damabe above the sacral cord |
|
Definition
|
|
Term
what type of bladder is created by damage of the sensory nerves flaccid |
|
Definition
|
|
Term
what are three major drugs that enhance NMJ blockers |
|
Definition
CCB halothane aminoglycocides |
|
|
Term
what is a common indication for scopolamine use |
|
Definition
|
|
Term
what are 6 major SE of estrogen treatment |
|
Definition
nausea vomiting endometrial hyperplasia DES- clear cell CA in daughters |
|
|
Term
3 main SE of progesterone tx |
|
Definition
hirsturism increased LDL and decreased HDL weight gain and acne depression |
|
|
Term
what type of blood and liver disorder can result from OPCs |
|
Definition
tumor of liver benign adenoma
clots |
|
|
Term
what color are gram positive after gram stain |
|
Definition
first step: crystal violet stains blue purple last step: safranin changes it to blue violet |
|
|
Term
what triggers classical and alternate pathway for complement system |
|
Definition
classic: antigen antibody complexes
alternate: endotoxin, cobra venom, fungi capsules |
|
|
Term
compare botulinum toxin and tetanospasmin where is it made |
|
Definition
botulinum: muscle flaccid, produced in body
tetanus: muscle spasm, preformed toxin |
|
|
Term
compare and contrast hypotonic dehydration and hypertonic dehydration in terms of ICV and ECV and causes |
|
Definition
hypotonic: increased ICV, decreased ECV, osmotic diarrhea, vomiting, addisons (Na loss)
hyper: decreased ICV, increased ECV, sweat, DI (water loss) |
|
|
Term
what organ is ACE found in |
|
Definition
|
|
Term
what part of the nervous system is activated by LSD |
|
Definition
|
|
Term
what is the street drug that causes agressive, fearless behavior |
|
Definition
|
|
Term
what opioid receptors causes analgesia, sedation, and respiratory depression |
|
Definition
analgesia and respiratory depression - Mu sedation - kappa |
|
|
Term
besides pain control what can codine do |
|
Definition
|
|
Term
how does fentanyl compare to morphine in potency |
|
Definition
|
|
Term
what neurotransmitter does TCA block |
|
Definition
|
|
Term
what are 3 foods high in tyramine |
|
Definition
|
|
Term
what are indications for use of lithium |
|
Definition
|
|
Term
what is the effect of nicotine on blood pressure |
|
Definition
low dose increases it high dose decreases it |
|
|
Term
what type of reflex is define as visceral stimuli by making a response in somatic structures innervated by the same vertebral segment |
|
Definition
|
|
Term
what type of reflex is occuring when a chronic biceps strain results in respiratory difficulties secondary to diaphragm dysfunction |
|
Definition
|
|
Term
what is then sympathetic collateral ganglion associated with the greater splanchnic nerve |
|
Definition
|
|
Term
what is the sympathetic collateral ganglion associated with the lesser splanchnic nerve |
|
Definition
|
|
Term
what is the sympathetic collateral ganglion associated with the least splanchnic nerve |
|
Definition
|
|
Term
what nerve root innervates the small intestine with the exception of part of the duodenum |
|
Definition
|
|
Term
if a pt had an ovarian cyst you might have dysfunction in visceral or somatic structures innervated by what nerve root? what cutaneous landmark would be included in possible reflex sites in the aformentioned situation |
|
Definition
|
|
Term
what effect does PS has on papillary muscles |
|
Definition
|
|
Term
what is the result of PNS on the adrenal medulla, GI sphinctors, and penis |
|
Definition
medulla - none relax GI sphinctors erect penis |
|
|
Term
what is the result of sympathetic stimulation of the skeletal muscle, arteries, salivary glands, and intestines |
|
Definition
muscle: increased glycogenolysis constrict arteries in skin (a1) relax arteries in muscles (B2) thicken salivary secretions decrease motility and secretion |
|
|
Term
what are 5 major physiologic effects that stimulated H1 receptors have |
|
Definition
nasal and bronchial mucous bronchiole constriction intestinal smooth muscle contraction stimulate sensory nerve endings vasodilation |
|
|
Term
what is the main physiologic effect of stimulated H2 |
|
Definition
increase HCl inthe stomach |
|
|
Term
what anesthetic agent has the potential to cause malignant hyperpthermia |
|
Definition
|
|
Term
besides supporting homeostasis, maintaing healthy metabolism, and supporting the whole patient what is the FIRST step in treating any dysfunctions involving facillitated spinal cord segments |
|
Definition
treat dysfunctional segment |
|
|
Term
after treating the dysfunctional segment, what are the next three steps in treating a facillitated dysfunction |
|
Definition
decrease hyperSNS fluid balance manage PNS |
|
|
Term
describe how rib raising has effect it does |
|
Definition
alters pressure on sympathetic chain fascia eound rib head is same as around sympathetic chain |
|
|
Term
in decreasing sympathetic contribution to a facilitated segment, what structures should be assessed after rib raising |
|
Definition
|
|
Term
name the collateral ganglia |
|
Definition
preaortic celiac superior mesenteric inferior mesenteric cervical |
|
|
Term
why do all cervical ganglia result in heart problems |
|
Definition
they all contribute to the cardiac plexus |
|
|
Term
which chapmans points are used for assessment and which for treatment |
|
Definition
anterior assess posterior treat |
|
|
Term
where is the chapmans reflex point for the sinuses |
|
Definition
|
|
Term
where is the chapmans reflex point for the liver |
|
Definition
costeosternal of 5 and 6 on right |
|
|
Term
where is the chapmans reflex point for the appendix |
|
Definition
|
|
Term
where is the chapmans point for the retina |
|
Definition
|
|
Term
what structures comprise the clinical throacic inlet |
|
Definition
|
|
Term
what 4 diaphragms should be assessed and released when adressing lymph drainage |
|
Definition
cervicothoracic craniocerivcal pelvic abdominal |
|
|
Term
what should always be done first lymph pumps or diaphragms |
|
Definition
|
|
Term
what are 4 anatomic transition sites of fascia, in common compensatory which way to each go |
|
Definition
craniocervical - left cervicocthoracic - right thoracolumbar - left lumbosacral - right |
|
|
Term
what nerve roots make the pelvic splanchnic nerve |
|
Definition
|
|
Term
what is the parasympathetic innervation to the mucous membrane of the sinuses and nasal mucosa |
|
Definition
|
|
Term
what cranial nerve is affected by manipulation of the sphenopalatine gangliona |
|
Definition
|
|
Term
what structure may be manipulated to balance the vagus nerve |
|
Definition
|
|
Term
what is the sympathetic innervation to the pancreas |
|
Definition
|
|
Term
what is the symptathetic innervation to the gallbladder |
|
Definition
|
|
Term
what is the primary method for modulating the pelvic splanchnic nerves |
|
Definition
|
|
Term
what are the three components of the primary respiratory mechanism |
|
Definition
|
|
Term
what are the dural attachments |
|
Definition
cranial bones foramen magnum C2-3 S1 posterior |
|
|
Term
in craniosacram extension what happens to the midline bones and cranial diameter and sacrum |
|
Definition
midline paired bones internally rotate nutation of sacrum increased AP diameter |
|
|
Term
in cranial torsion what is the dysfunction named for |
|
Definition
greater wing of sphenoid that is superior |
|
|
Term
what is the purpose of th eCV4 method |
|
Definition
increase CRI by decompressing the SBS |
|
|
Term
what type of cranial dysfunction is marked by cephalic deviation of the sphenoid |
|
Definition
|
|
Term
DOC petit mal seizure, aka |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
metoclopramide and odanzatron |
|
|
Term
|
Definition
|
|
Term
|
Definition
diarrhea, draws water in via osmosis |
|
|
Term
to what calss of drugs (2 answers) to lorazepam, diazepam, triazolam and chlordiazepoxide belong |
|
Definition
anoxiolytic benzodiazepines |
|
|
Term
barbituates have high suicide potentional, what is the common way for them to cause death in overdose |
|
Definition
decrease chemoreceptor response to CO2 causing hypoxia |
|
|