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Serotonin R Drugs
agonists/antagonists
6
Pharmacology
Professional
09/30/2009

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Cards

Term
Buspirone
Definition
5HT 1A Agonist (via Gi). Anxiolytic.
Term
Sumatriptan
Definition
5HT 1B/1D Agonist (via Gi). For migraines.
Term
Cyproheptadine
Definition
5HT 2A Antagonist (Gq ptwy). For carcinoid syndrome, 5HT syndrome, or cold-induced urticaria.
Term
Ketanserin
Definition
5HT 2A Antagonist (Gq ptwy). Also blocks alpha adrenoceptors. Blocks VSM contraction, platelet aggregation. (Anti-HTN in Europe).
Term
Ondansetron
Definition
5HT3 Antagonist (Na/K channel). Prevents N&V after surgery and in chemotherapy.
Term
Granisetron
Definition
5HT3 Antagonist (Na/K channel). Prevents N&V after surgery and in chemotherapy.
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