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serology test 1- cold agglutin
cold agglutinins
18
Health Care
Undergraduate 4
04/05/2009

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Cards

Term
who discovered cold agglutinins in 1903?
Definition
Landsteiner
Term
antibodies that react best with RBC's at temperatures of 0-4C
Definition
cold agglutinins
Term
two groups of cold agglutinins
Definition
pathogenic and nonpathogenic
Term
what kind of cold agglutinins are active to a temperature of 10 to 15C?
Definition
nonpathogenic
Term
what kind of cold agglutinins are present in all normal sera?
Definition
nonpathogenic
Term
Anti-I, anti-H, and rarely other specificities
Definition
nonpathogenic
Term
anti-I, anti-i, and rarely other specificities
Definition
pathogenic
Term
what kind of cold agglutinins are found in cases of chronic cold agglutinin disease?
Definition
pathogenic
Term
a condition with a high titer of cold agglutinins causing intravascular agglutination when blood is cooled in peripheral parts of the body exposed to cold.
Definition
cold agglutinin syndrome
Term
titer of cold agglutinins in disease?
Definition
titer in thousands or millions
Term
titer of cold agglutinins in chronic parasitic infections
Definition
up to 1:500
Term
cold agglutinin syndrome occurs in what two groups of people?
Definition
the elderly and post infectious cold agglutinin syndrome
Term
two infections that can lead to post infectious cold agglutinin syndrome
Definition
mycoplasmal pneumonia and infectious mononucleosis
Term
what percent of mycoplasmal pneumonia patients have cold agglutinins present?
Definition
55%
Term
what percent of infectious mononucleosis patients have anti-i cold agglutinins?
Definition
50%
Term
what specificity are cold agglutinins produced in mycoplasmal pneumonia?
Definition
anti-I
Term
serological testing for cold agglutinins is frequently used to screen for what?
Definition
atypical pneumonia
Term
when are cold agglutinins absorbed by RBCs?
Definition
in the cold
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