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Sepsis and Circulatory Shock
Special Pops Final Exam
13
Pharmacology
Professional
05/05/2014

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Cards

Term
how quickly must shock be treated to increase survival
Definition
admin fluids >60 mL/Kg within FIRST hour or presentation significantly reduces mortality in peds
Term
common causes of cardiogenic shock
Definition
congenital heart dx, recent cardiac surgery, recent viral illness, late septic shock
Term
early onset empiric neonatal sepsis treatment
Definition
AMP + aminoglycoside OR 3rd gen Cef (except ceftriaxone--> kernicterus)
Term
LATE onset empiric neonatal sepsis
Definition
if discharged, same as home; if hospitalized, Ceftaxime + vanco (staph) OR cefotaxime + aminoglycoside (ecoli, klebsiella,hflu)
Term
factors affecting treatment of neonatal sepsis
Definition
alterations in PK/PD within peds, antibiotic spectrum of activity, site infection, pathogen, past ABx history, regional/ institutional resistance, potential toxicities
Term
venous return is decreased
Definition
lack of fluid in the vascular space, causing decreased ventricular filling
Term
ventricals receive less blood
Definition
decreasing stroke volume
Term
heart rate increases
Definition
compensating for diminished stroke volume and results in poor cardiac output and blood pressure
Term
fluid and blood loss continues
Definition
heart rate will not be able to compensate for decreased SV
Term
hypovolemic shock
Definition
results in inadequate tissue perfusion
Term
hypovolemia's impact on shock:
Definition
decreased pre-load and loss of volume (blood/ water loss external/internally)
Term
hypovolemia
Definition
primary cause of shock in peds worldwide
Term
causes of hypovolemia
Definition
trauma, vomiting, diarrhea, poor appetite, diabetes
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