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Section 6: Developmental Mechanisms
Chapter 14 Concepts 1-3
24
Biology
Undergraduate 1
02/23/2013

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Term
development
Definition
the process bu which a multicellular organisms, beginning with a single cell, goes through a series of changes, taking on the successive forms that characterize its life cycle
Term
stem cell
Definition
an undifferentated cell that is capable of continuous proliferation
*a stem cell generates more stem cells and a large clone of differentiated progeny cells
Term
totipotent stem cell
Definition
possessing all the genetic information and other capacities necessary to form an entire individual
Term
pluripotent stem cell
Definition
having the ability to form all of the cells in the body
Term
multipotent stem cell
Definition
having the ability to differentiate into a limited number of cell types
Term
embryonic stem cell
Definition
a pluripotent cell in the blastocyst
Term
induced pluripotent stem cell
Definition
multipotent or pluripotent animal stem cells produced from differentiated cells in vitro by the addition of several genes that are expressed
Term
determination
Definition
in development, the process whereby the fate of an embryonic cell or group of cells is set
Term
differentiation
Definition
the process whereby originally similar cells follow different developmental pathways; the actual expression of determination
Term
induction
Definition
in embryonic development, the process by which a factor produced and secreted by certain cells determines the fates of other cells
Term
inducer
Definition
A) compound that stimulates the synthesis of a protein
B) in empryonic development, a substance that causes a group of target cells to differentate in a particular way
Term
morphogen
Definition
a diffusible substance whose concentration gradient determines a developmental pattern in animals and plants
Term
cytoplasmic determinant
Definition
gene products whose spatial distribution may determine such things as embryonic axes
Term
cytoplasmic segregation
(asymmetric inheritance of cytoplasmic determinants)
Definition
the asymmetrical distribution of cytoplasmic determinants in a developing animal embryo
Term
polarity
Definition
the difference between one end of an organism or structure and the other
Term
reproductive cloning
Definition
Term
therapeutic cloning
Definition
Term
induced pluripotent stem cells
(iPS cells)
Definition
multipotent or pluripotent animal stem cells produced from differentiated cells in vitro by the addition of several genes that are expressed
Term
segmentation gene
Definition
genes that determine the number and polarity of body segments
Term
hox gene
Definition
conserved homeotic genes found in vertebrates, Drosophila, and other animal groups. Hox genes contain the homeobox domain and specify pattern and axis formation in these animals
Term
morphogenesis
Definition
the development of form; the overall consequence of determination, differentiation, and growth
Term
pattern formation
Definition
the organization of differentiated tissues into specific structures such as wings
Term
necrosis
Definition
premature cell death caused by external agents such as toxins
Term
apoptosis
Definition
a series of genetically programmed events leading to cell death
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