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First encountered sickle cell anemia in a patient's blood |
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Chromosome theory also discovered similarities between inheritance of the genes discovered by Mendel aswell as behavior of chromosomes in meosis and fertilization |
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Discovered the ABO blood group |
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studied alkaptomria a diesease in humans which makes urine black when it hits the air. Concluded it was inherited and that it was a "inborn error of metabolism." |
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used Neurospora crassa (orange bread mold) |
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discovered the structure of DNA based off of Franklin's finidngs |
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discovered structure of DNA through x ray diffraction. |
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found a substance that could genetically transform pneumonia bacteria throug hand expirement with mice. the bacteria was streppococcus pneumoniae and it has a rough and soft form |
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Avery, MacLeod, & McCarty |
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discovered DNA as the molecule that transforms rough streppococcus pneumoniae to the infective form |
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found final evidence that established DNA as the hereditary molecule |
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used garden peas to study patterns in inheritance. Also found fundamental rules that govern inheritance. |
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used a fruit fly to investigate Mendel's principles in humans |
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took pus from bandages to study white blood cells and called what he found nuclein |
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discovered that the nitrogenous bases have fixed ratios. A=T, G=C |
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showed that DNA replication is semi conservative |
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discovered short fragments of DNA during the linking of polypeptides chain |
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discovered the mechanism for DNA synthesis through e.coli |
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discovered how chromosomes are protected by telomeres and the enzyme telomerase |
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conservation of telomere protein function in non mammal model systems. also identified all Xenopus genes for all the "shelterin" |
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