Salicylates

-          Acute chronic pain, anti inflammatory

-          Inhitbit the formation of prosteglanden

-          S/E

o   Prolonged bleeding time, salyclism-when its toxic

o   Salyclism- tinnitus, confusion, decreased respiratory and kidney function, accessive bleeding, or coma

§  NO ANTIDOTE

-          Reyes syndrome- not for kids under 17

-          Pregnancy D

-          Have with milk

-          Stop a week before surgery

-          Acetylsalicylic acid (ASA)

o   Aspirin

§  MI treatment caused by clot

§  Anti-platelet prevent heart attacks, strokes caused by clot

·         Daily low dose

§  81 mg/ 325 enteric coated

  Indomethacin

§  Also used for gout