Term
What are the three major characteristics of non-inflammatory diarrhea? |
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Definition
No fecal WBCs
Infection in proximal SI
Watery Diarrhea |
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Term
What is one major distinguishing feature between ETEC and Vibrio cholerae? |
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Definition
Vibrio is oxidase +
ETEC is not |
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Term
Flashback from s3... What does ST and LT increase respectively? |
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Definition
ST increases cGMP
LT increases cAMP
Recall that both of these leads to hypersecretion of Cl- which inhibits Na absorption which keeps water in the intestinal lumen resulting in watery diarrhea. I think. |
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Term
I'll bet you $5 EC that this will be on mini 2.
If you plate ETEC and Vibrio on Maconke Agar what would each colony look like and why? |
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Definition
ETEC produces pink colonies because it can ferment lactose
Vibrio produces clear colonies because is cannot ferment lactose. |
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Term
What type of pH does Vibrio perfer? |
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Definition
Vibrio is an alkalinophile and likes a pH around 9 |
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Term
What does halophile mean and what bug can this apply to? |
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Definition
Halophile means it likes increased salinity.
Vibrio is a halophile. It also likes a temp between 10-30 degrees which is comprable to most marine environments. |
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Term
How are vibrio strains classified? |
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Definition
By their LPS (O-antigen)
O1 and O139 cause cholera epidemics
O1 can either be El Tor or Classical |
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Term
What is required for Vibrio to produce CTX and TCP toxins? |
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Definition
The genetics for it are presented by an integrated bacteriophage. |
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Term
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Definition
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Term
What has a longer incubation period ETEC or Vibrio? |
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Definition
Vibrio (16-72 hrs) has a longer incubation period than ETEC |
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Term
How do you culture Vibrio? |
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Definition
Thiosulface bile salt sucrose (TCBS) which goes from green to yellow in the presance of Vibrio. |
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Term
Vibrio will kill the patient in 4-12 hours unless you give them fluids.
Thats just a fact. Pretty crazy huh? |
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Definition
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