Term
Define the 4 stages of General Anesthesia |
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Definition
1. Analgesia
2. Stage of excitement: irregular respiration
3. Stage of surgical anesthesia: normal respiration
4. Stage of medullary depression: no respiration |
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Term
What does a higher MAC translate to in terms of potency? |
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Definition
Higher MAC means less potency. |
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Term
What is the MOA of most inhailed anesthetics? |
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Definition
Opens the GABAa regulated Ca channel. |
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Term
This general anesthetic has a higher solubilty in fat than blood. |
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Definition
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Term
What are two important adverse effects of Halothan? |
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Definition
Fulminant hepatic necrosis
Malignant hyperthermia (+ succinylcholine) |
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Term
So it turns out hiring an anethesiology off of craigs list was a bad idea. Your patient has just started to experience seizures. What general anesthetic do you think caused this? |
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Definition
Probably Isoflurane. Recall that this drug |
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Term
This drug should not be used in Automatic Anethesia Machine Despenser Rhingies if the AAMDT uses dissicated CO2 absorbant. |
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Definition
Sevoflurane. It may cause airway burns |
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Term
Halothane can cause Malignant Hyperthermia. What is the treatment for this and what is its MOA? |
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Definition
Dantrolene. It blocks calcium release from the sarcoplasmic reticulum.
Recall that Malignant Hyperthermia presents with hyperthermia, tachycardia, metabolic acidosis, hypercalcemia, muscle contraction and myoglobinura. |
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Term
An anethetic that has a 100% MAC and can cause diffusion hypoxia. |
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Definition
Nitrous Oxide
The diffusion hypoxia occurs when NO is quickly removed from the patient's ventilator and NO from the plasma rapidly diffuses into the alveoli and replaces oxygen. |
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