Shared Flashcard Set

Details

S3 Ross Anxiolytics Sedatives and Hyponotics
Coffin
20
Pharmacology
Professional
11/12/2009

Additional Pharmacology Flashcards

 


 

Cards

Term
A class of drugs that decreases REM sleep. Withdrawal from this drug has a rebound effect to give you nightmares.
Definition
Barbiturates.
Term
This class of drugs binds to a site on the GABA A channel and alters it to allow for more effective GABA binding.
Definition
Benzodiazepines.
Term
An odd side effect of BZs is...
Definition
Paradoxical excitement and CNS stimulation.
Term
A second generation anxiolytic that is a partial agonist as 5HT 1A receptors is...
Definition
Buspirone. This drug works over time which is the only downside to this drug.
Term
This drug increases aldehye dehydrogenase.
Definition
Disulfram. It causes flushing, nasuea, vomiting and hypotension when combined with alcohol.
Term
A competitive benzodiazepine receptor antagonist.
Definition
Flumazenil.
Term
This drug class causes you to spend more time in stage 2 of sleep over stages 3 and 4. Also increased brief awakenings, and an increase in total sleep time. You will also notice decreased REM and sleep latency.
Definition
Benzos
Term
A person who wakes up several times a night and has difficulty getting to sleep may be prescribed...
Definition
Zolpidem (Ambien). Note that you should only use this drug for 5 weeks.
Term
This drug shortens sleep latency and had a shorter half life so it can be used to help insomnia even as late as midnight.
Definition
Zaleplon (Sonata). This drug works on a GABA receptor, so you should not mix alcohol with it.
Term
A second generation hypnotic that is effective up to 12 months.
Definition
Eszopiclone.
Term
This drug helps Delayed Phase Sleep Disorder. Can be used in the elderly, ICU, and those who travel.
Definition
Ramelteon (Rozerem)
Term
This second generation hypnotic is a melatonin agonist (MT1)
Definition
Ramelteon (Rozerem)
Term
These three benzos under go phase II inactivation. What are the three drugs and why is this significant?
Definition

Outside The Liver

Oxazepam, Temazepan, Lorazepam

 

These drugs are good to give to the elderly and people with liver disease

Term
Between the benzos and barbs which ones increase the frequency of channel opening and which ones increase the duration of channel opening?
Definition

Benzos increase the frequency

 

Barbs increase the duration

Term
Name two drugs you would consider giving for Generalized Anxiety Disorder.
Definition
Diazepam and Buspirone
Term
Name drugs would you give for stress-related anxiety
Definition
Any benzos would be the preferred drug.
Term
Drugs or classes of drugs you would give for panic attacks
Definition
Alprazolam, SSRIs, TCAs, MAO-Is
Term
Drugs you could give for PTSD
Definition

SSRIs and MAO-Is.

 

Possibly benzos

Term
What do you NOT give for social phobias?
Definition
NO BENZOs FOR SOCIAL PHOBIA!
Term
So it turns out Elvis is not dead but just had sudden onset Agoraphobia. What drug would you prescribe?
Definition
Alprozolam
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