Term
A class of drugs that decreases REM sleep. Withdrawal from this drug has a rebound effect to give you nightmares. |
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Definition
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Term
This class of drugs binds to a site on the GABA A channel and alters it to allow for more effective GABA binding. |
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Definition
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An odd side effect of BZs is... |
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Definition
Paradoxical excitement and CNS stimulation. |
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Term
A second generation anxiolytic that is a partial agonist as 5HT 1A receptors is... |
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Definition
Buspirone. This drug works over time which is the only downside to this drug. |
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Term
This drug increases aldehye dehydrogenase. |
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Definition
Disulfram. It causes flushing, nasuea, vomiting and hypotension when combined with alcohol. |
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Term
A competitive benzodiazepine receptor antagonist. |
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Definition
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Term
This drug class causes you to spend more time in stage 2 of sleep over stages 3 and 4. Also increased brief awakenings, and an increase in total sleep time. You will also notice decreased REM and sleep latency. |
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Definition
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Term
A person who wakes up several times a night and has difficulty getting to sleep may be prescribed... |
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Definition
Zolpidem (Ambien). Note that you should only use this drug for 5 weeks. |
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Term
This drug shortens sleep latency and had a shorter half life so it can be used to help insomnia even as late as midnight. |
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Definition
Zaleplon (Sonata). This drug works on a GABA receptor, so you should not mix alcohol with it. |
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Term
A second generation hypnotic that is effective up to 12 months. |
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Definition
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Term
This drug helps Delayed Phase Sleep Disorder. Can be used in the elderly, ICU, and those who travel. |
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Definition
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Term
This second generation hypnotic is a melatonin agonist (MT1) |
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Definition
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Term
These three benzos under go phase II inactivation. What are the three drugs and why is this significant? |
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Definition
Outside The Liver
Oxazepam, Temazepan, Lorazepam
These drugs are good to give to the elderly and people with liver disease |
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Term
Between the benzos and barbs which ones increase the frequency of channel opening and which ones increase the duration of channel opening? |
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Definition
Benzos increase the frequency
Barbs increase the duration |
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Term
Name two drugs you would consider giving for Generalized Anxiety Disorder. |
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Definition
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Term
Name drugs would you give for stress-related anxiety |
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Definition
Any benzos would be the preferred drug. |
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Term
Drugs or classes of drugs you would give for panic attacks |
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Definition
Alprazolam, SSRIs, TCAs, MAO-Is |
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Term
Drugs you could give for PTSD |
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Definition
SSRIs and MAO-Is.
Possibly benzos |
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Term
What do you NOT give for social phobias? |
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Definition
NO BENZOs FOR SOCIAL PHOBIA! |
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Term
So it turns out Elvis is not dead but just had sudden onset Agoraphobia. What drug would you prescribe? |
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Definition
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