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Details

S3.M2.Pharm1,2
Autocoid Drugs
27
Pharmacology
Professional
06/25/2010

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Cards

Term
Ergotamine
Dihydroergotamine
Definition
5HT AGONIST
-analgesic-->migraine pain ONLY--> 1ST sign of attack otherwise ineffective
Term
Buspirone
Definition
5HT AGONIST
-anxiolytic to treat generalized anxiety disorder
Term
Sumatriptan
Definition
used for migraine and cluster headaches
Term
Phenothiazines and butyrophenones
Definition
5HT ANTAGONIST-->ANTIPSYCHOTICS
treatment of schizophrenia and mania
Term
Epoprostenol
Definition
Treatment of primary pulmonary hypertension
Term
Latanoprost
Definition
Treatment of open angle glaucoma
Term
Diphenhydramine
Definition
H1 antagonist
-potent local anesthetic
-prevent motion sickness
-used in PARKINSONS**
Term
Alprostadil
Definition
-used for erectile dysfunction
-treats PATENT DUCTUS ARTERIOSUS
Term
Cimetidine
Definition
H2 ANTAGONIST
-Blocks dihydrotestosterone binding to androgen receptor--> gynecomastia, loss of libido, impotence
-inhibits metabolism of estradiol
Term
Dinoprostone
Definition
-causes smooth muscle contraction in vagina
-ripens cervix to induce labor
Term
Misoprostol
Definition
-induce early abortion
-Treatment of NSAID-induced peptic ulcers
**given orally or vaginally
Term
Ergonovine
Definition
5HT AGONIST
-Postpartum bleeding-->placental delivery
-Diagnosis of variant angina-->coronary angiography
Term
Carboprost
Definition
-Induction of 2nd trimester abortion
-controls postpartum hemorrhage
Term
Loratadine
Definition
2nd generation H1 receptor antagonist--> very effective in treatment of ALLERGIES if taken before exposure
**NO CNS, NO DROWSINESS
Term
Cyproheptadine
Definition
5‐HT Antagonists
-blocks serotonin receptors
-smooth muscle manifestations of carcinoid tumor and cold-induced urticaria
Term
Cromolyn
Definition
o Reduce the degranulation of mast cells caused by immunologic triggering-->reduce the release of histamine
Term
Nedocromil
Definition
o Reduce the degranulation of mast cells caused by immunologic triggering-->reduce the release of histamine
Term
Ondansetron
Definition
5‐HT Antagonists
-prevent the nausea and vomiting associated with surgery and cancer chemotherapy
Term
Promethazine
Definition
-alpha-receptor blocking effects
-potent local anesthetic
-prevent motion sickness-->SEDATIVE
Term
Ritanserin
Definition
5‐HT Antagonists
-Alters bleeding time and reduces thromboxane formation by altering platelet function
Term
Phenoxybenzamine
Definition
5‐HT Antagonists, ALPHA Antagonist
-manage pheochromocytoma
Term
Cyclizine, Meclizine
Definition
H1 antagonists (long acting) – Prevent motion sickness
Term
Dimenhydrinate
Definition
H1 antagonist
(Dramamine) – Treatment of motion sickness
Term
Famotidine
Definition
potent H2 ANTAGONIST
Term
Nizatidine
Definition
H2 ANTAGONIST
high bioavailability
Term
Ranitidine
Definition
H2 antagonist
Term
***ANTACIDS reduce the absorption of H2 ANTAGONISTS
Definition
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