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Depression 2D6 inhibitor Kids, Long 1/2 life, Pulmonary HTN in neonates |
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SNRI ghost tablet ADR-dd bp increase, discontinuation syndrome |
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SNRI Ghost tablet ADR-dd bp increase, discontinuation syndrome |
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SNRI +Pain from DM neuropathy, fibromyalgia, chronic msc pain |
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SSRI+Partial 5HT Receptor agonist last line depression do not use with MAOI |
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BZD anxiety +seizures, anesthesia, elderly use |
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Antidepressant CY2D6 inhibitor Good for sexual dys, wt gain, smoking Bad for anxiety, seizures |
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Antidepressant +Insomnia ADR- QT and Priapism |
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Antidepressant +Insomnia or Anorexia ADR-Sedation at low dose, wt gain |
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TCA (tertiary) MDD+Enuresis in kids |
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TCA (tertiary) +OCD Not for MDD |
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TCA (tertiary) MDD+Insomnia sleep maintenance |
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MAOI (A) depression + Hyperphagia/Hypersomnia ADR-Tyramine foods |
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MAOI (B) High dose=MDD, Low dose =PD 24h patch ADR c tyramine rich foods! |
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Bipolar Disorder Intrx- TZD, Nsaid, aceI ADR-Tremor, Nocturia, Teratogen D Monitor Renal, Ecg, preggers, thyroid |
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Schizo, mania, hiccups Intrx-2D6 and 3A4 inhibito, QT agent ADR-EPS, NMS, QTC, Prolactin increase |
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Schizo, Tourettes, sedation (depot) potent Intx- 2D6 and 3A4 inhibitor, qt agents adrs- EPS, NMS, QTC, prolactin |
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Atypical antipsychotic Refractory schizophrenia Adr-Wt gain, seizure, *Agranulocytosis |
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Atypical antipsychotic +Depression Wt Gain! |
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Atypical antipsychotic +Depression QT prolongation |
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Atypical antipsychotic QTc |
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Atypical Antipsychotic +depression |
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Atypical antipsychotic dont use it, allergic rxn |
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Atypical antipsychotic QTc |
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Antihistamine hypnotic Long onset and duration tolerance may develop |
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Antihistamine hypnotic Long onset and duration tolerance may develop |
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Hypnotic BZD Short onset and short duration Teratogen |
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NBRA hypnotic sleep onset and maintenance shortest duration falls, amnesia, and allergic rxn |
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NBRA hypnotic sleep onset and maintenance adr-falls, amnesia, allergic rxn |
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NBRA hypnotic sleep onset and maintenance adr-falls, amnesia, allergic rxn |
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Melatonin Agonist For falling asleep, fallers, travelers, chronic insomnia, or abuse concerns |
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Stimulant ADHD-short, int, and long acting |
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Stimulant ADHD-Short and Long acting |
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Stimulant ADHD-Short and int acting |
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Amphetamine-Dextroamphetamine |
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Stimulant (adderall) ADHD- Short and long acting (double pulse) |
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Stimulant ADHD Long acting |
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Non Stimulant ADHD- No abuse potential, can take at night, less effective Black box for suicidal ideation |
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other ADHD drug Kids adjunct or replacement to stimulants |
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other adhd drug adjunct or replacement to stimulants intx- B blockers and CCBs=bradycardia Adr-sedation and nightmares |
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Old cholinesterase inhibitor for dementia |
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cholinesterase inhibitor for mild-mod dementia Intx- DO not use with anticholinergics |
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NMDA Receptor Agonist for moderate-severe dementia Tamps down brain excitation via glutamate |
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Migraine SQ, nasal spray, and fastest onset |
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Migraine tablet slowest onset, lasts longest |
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Migraine tablet slowest onset, lasts longest |
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Migraine ergot For people not responding to triptans |
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Also Antiemetic c migraine IV/IM adr- akasthesia! |
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Parkinson *On off syndrome *Wearing off syndrome works on akinetic>tremor>postural instability |
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Parkinson Blocks levodopa --> dopamine systemically decrease N/V and orthostatic htn |
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Dopamine Receptor Agonist +RLS |
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Dopamine Receptor Agonist +RLS |
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Dopamine Receptor Agonist +RLS |
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Dopamine Receptor Agonist severe immobility *makes you vomit! |
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MAOI (B) For Parkinsons tyramine food htn crisis |
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Anticholinergic for parkinsons treat drug induced EPS and drooling |
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Anticholinergic for parkinsons Treat drug induced EPS and drooling |
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NMDA Antagonist for parkinsons for ldopa induced dyskinesias adrs- Peripheral edema and Livedo reticularis (high dose) |
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Na Channel antiepileptic for chronic pain, neuralgia, may make absence and myoclonic sz worse Autoinduce 2c9 and 3a4 |
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Na Channel antiepileptic same as CBZ but greater hyponatremia |
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Na Channel antiepileptic Prevent early seizure after TBI/NS Autoinduces 2C9 and 3A4 ADR- gingival hypertrophy, fever, BMS, hypertrichosis |
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Na Channel antiepileptic like phenytoin but faster admin and less IV complications |
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Na Channel antiepileptic for Newly diagnosed absence and bipolar maintenance |
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Na Channel antiepileptic PR Prolongation! Euphoria=Sched V |
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Na Channel antiepileptic *Monitor Bicarb adr-heat stroke, m acidosis, stones |
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Na Channel antiepileptic Atonic Seizures *Shortens QT |
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K channel antiepileptic ECG monitor for QT Euphoria=sched V substance |
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Ca channel antiepileptic Absence Seizures Monitor cbc and lft adr behavioral, hyperactivity adhd and psychoses |
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Ca channel antiepileptic Post-herpetic neuropathy, RLS *Not metabolized, increase myoclonic seizure |
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Ca channel antiepileptic Firbromyalgia and neuropathy *not metabolized, wt gain, sched V for euphoria |
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Gaba AED autoinducer of 2c9 and 3a4 monitor cbc, lfts, ca, vit d |
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gaba aed BZD for *Atonic Seizure |
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Gaba AEd BZD for *atonic seizures |
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gaba aed monitor cbc and cmp New onset *Status Epilepticus/seizures with off label use |
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Gaba aed *Monotherapy for infantile spasm adr-*Retinal toxicity |
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Use for Mania, migraine proph, AED Monitor cbc and ammonia adr-parkinsonism, wt gain, hepatotox, androgens, teratogen=spina bifida, cleft palate |
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NMDA Antagonist (monitor bicarb) Migraine Proph, wt management adr hypothermia, m acidosis, kidney stones *Hypospadias! |
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Last line seizure med LGS Adr- Fatal aplastic anemia, require written consent Hepatic failure |
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Prevent early seizures following tbi/ns adr-behavioral |
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