Term
What is needed to be included in the viron with all -RNA viruses? |
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Definition
RNA Dependant RNA polymerase |
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Definition
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What is the main vector for rabies in the US? |
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Definition
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Term
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Definition
Getting bit from a rabid animal |
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Term
In an infected person with Rabies, where would you swab to test for the presence of rabies? |
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Definition
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Term
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Definition
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Definition
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Term
What major disease does the Filo virus cause? |
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Definition
Ebola (and Marburg but more rare) |
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Term
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Definition
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Pt presents with bleeding from the eyes, ears, mouth, nose, and downstairs... what do they have? |
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Definition
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Term
How is Ebola transmitted? |
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Definition
Respiratory and direct contact(blood) |
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Term
What part of the world is Ebola usually found? |
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Definition
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Term
How is the Bunya virus transmitted? |
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Definition
mosqutios rodents and ticks (know Rodents for exam) |
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Term
How do you get Hantavirus Pulmonary Syndrom (HPS)? |
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Definition
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Term
What is central to the pathogensis of the HSP virus? |
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Definition
Functional impairment of vascular endothelium |
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Term
How do the symptoms of HSP layout? |
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Definition
First you get a non specific illness (flu like with SOB and Tachycardia) and then BOOM, you enter the cardiopulmonary phase and shit goes down. |
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Term
What are 3 observations to diagnose HPS? |
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Definition
1. Area of country 2. Massive pulmonary infection 3. Death |
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Term
What virus is appears studded due to ribosomal attachment? |
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Definition
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Term
What 3 viruses/infections does the Reo Virus cause? |
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Definition
1. Reovirus 2. Rotovirus 3. Colorado Tick Fever Virus |
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Term
What is special about the structure of the reo virus? |
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Definition
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Term
How is the rotovirus transmitted? |
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Definition
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Term
What diease does the rotovirus cause? |
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Definition
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Term
What genera of influenza (orthomyxovirus) causes infections of humans/animals/both? |
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Definition
Influenza A= both Influenza B+C= humans only |
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Term
What is hemagglutinin (HA), where is it located, and what types of viruses have it? |
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Definition
HA= protein on the influenza virus which allows the cells to enter by binding to sialic acid on the host cell. Its located on the envelope on the virus |
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Term
What is neuramindiase (NA), where is it located, and what ypes of viruses have it? |
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Definition
NA= enzyme which breaks down mucus that is located on the surface of the envelope on the influenza virus. It also, detaches sialic acid from HA so the virus can bind to other cells. |
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Term
What type of phenomena occurs about every decade with respect to influenza viruses? |
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Definition
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Term
What envelope protein is ALWAYS altered in a antigentic shift? |
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Definition
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Term
Antigenic shift only occurs in which virus (be specific)? |
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Definition
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Term
How does antigenic shift happen? |
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Definition
Influenza A viruses of 2 different strain infect the same cell. Each virus has 8 different segments that recombine to form a new virus that no one has antibodies for....uh oh |
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Term
What type of influenza virsus can do Antigenic drift? |
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Definition
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Term
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Definition
Small changes in the AA sequence of HA and NA due to RNA polymerases having no proof reading mechanisms. |
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Term
What is responsible for Pandemics? |
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Definition
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Term
What is responsible for epidemics? |
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Definition
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Term
How is the influenza virus transmitted? |
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Definition
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Term
What is characteristic of the flu? |
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Definition
ABRUPT onset of high fever (102-104) Headache
*No coryza associated with an influenza infection |
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Term
Once influenza enters the blood, what is its next target? |
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Definition
Nothing! Its only confined to the RT! |
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Term
What is the influnza's virus pathogensis technique? How does it cause disease? |
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Definition
Cilia are destroyed as well as mucus membrane secreting cells. |
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Term
What is the most common secondary infection with a influenza infection? |
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Definition
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Term
What form of vaccine is the flu mist? |
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Definition
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Term
What 3 infections are caused by the Paramyxovirus? |
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Definition
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Term
What virus cause the Measles? |
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Definition
Morbilli virus (Paramyxovirus) |
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Term
How are the measles transmitted? |
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Definition
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Term
What are the 3 clinical symptoms does a pt with the measles present with? |
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Definition
3C's: Cough Conjunctivitis Coryza (photosensitivity sometimes too) |
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Term
What is the vaccine status for the measles? |
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Definition
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Term
BUZZWORD: Koplik's Spots (on inner cheek) |
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Definition
Measles (morbilli virus; paramyxovirus) |
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Term
When are the measles contagious the most (with respect to the onset of symptoms) |
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Definition
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Term
Where does the measles rash start? |
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Definition
Behind the ears and travels down |
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Term
What causes Subacute Sclerosing pan Encepalitis (SSPE)? |
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Definition
Measles (morbilli virus; paramyxovirus) |
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Term
What do you see first with measles, the rash or koplik's spots? |
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Definition
Koplik's spots in the mouth |
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Term
What can you see on cell cultures of measles patients? |
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Definition
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Term
BUZZWORD: Croup (Seal Cough) |
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Definition
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Term
How is the parainfluenza virus transmitted? |
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Definition
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Term
What 3 clinical symptoms can you observe on pts with a infection with the parainfluenza? |
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Definition
Croup, tachypnea, tachycardia |
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Term
What will you see notice in a host cellular culture of a pt who is infected with parainfluenza? |
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Definition
host cell fusion (syncitia). It also causes hemaagglutination |
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Term
What parainfluenza serotypes give croup? |
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Definition
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Term
What parainfluenza serotype is active all year round? |
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Definition
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Term
What is a tell tale sign of MUMPS? |
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Definition
Huge ass parotid gland swelling (bilateral) |
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Term
Route of Mumps infection? (starts where.... can go to where) |
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Definition
Start in epitheial cells of URT and will go to parotid glands. Next it can enter the blood and go to testes can cause serility |
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Term
Why is it dangerous for men to have mumps? |
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Definition
They could become sterile (orchiditis) |
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Term
How is mumps transmitted? |
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Definition
Respiratiory droplets / direct contact |
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Term
BUZZWORD: Bilateral parotiditis |
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Definition
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Term
What is the vaccine called for MUMPS? |
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Definition
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Term
What is the most common cause of fatal respiratory tract infections in infants? |
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Definition
Respiratory Syncital Virus (RSV) |
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Term
What types of HA and NA does RSV have? |
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Definition
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Term
What can RSV do that makes it so dangerous? |
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Definition
It can form mucus + fibrin plugs that clog the airway. |
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Term
Where is RSV's target once it hits the blood? |
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Definition
Nowhere, its localized to the URT |
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Term
When is RSV usually transmitted (time of year)? |
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Definition
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Term
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Definition
Respiratory droplets and hands via fomites |
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Term
BUZZWORD: Prominent Runny Nose |
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Definition
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