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*SLE only (60%) *An indicator of disease activity and lupus nephritis *SLE flare (dec C3, C4-- inc dsDNA= acute flare) |
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**Drug induced lupus (arthritis + fever) Most commonly associated with 1)Hydralazine (often ANA negative) 2)Isoniazide 3)Procainamide 4)Quinidine |
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*Neonatal lupus (congenital heart block) **Sjogren in 3% of ANA-neg lupus |
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100% mixed connective tissue disease (MCTD) |
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Primary Biliary Cirrhosis |
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