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Rheumatology
Rheumatology
10
Medical
Professional
12/09/2014

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Cards

Term
Anti-ds-DNA
Definition
*SLE only (60%)
*An indicator of disease activity and lupus nephritis
*SLE flare (dec C3, C4-- inc dsDNA= acute flare)
Term
Anti-Smith
Definition
*SLE only (25-30%)
Term
Anti-histone
Definition
**Drug induced lupus
(arthritis + fever)
Most commonly associated with
1)Hydralazine (often ANA negative)
2)Isoniazide
3)Procainamide
4)Quinidine
Term
anti-topoisomerase abs
Definition
scl-70
SCLERODERMA
Term
anti-centromere
Definition
CREST
Term
anti-Ro (SSA)
Definition
*Neonatal lupus (congenital heart block)
**Sjogren
in 3% of ANA-neg lupus
Term
Anti-La (SSB)
Definition
*Sjogren
Term
Anti-RNP
Definition
100% mixed connective tissue disease (MCTD)
Term
anti-mitochondrial abs
Definition
Primary Biliary Cirrhosis
Term
anti-smooth muscle abs
Definition
Autoimmune hepatitis
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